Application of DNP-enhanced solid-state NMR to studies of amyloid-β peptide interaction with lipid membranes

Fibrillization of 40-residue β-Amyloid Peptides in Membrane-Like Environments Leads to Different Fibril Structures and Reduced Molecular Polymorphisms

(2020) Qinghui Cheng et al.   Biomolecules

Fibrillar and Nonfibrillar Amyloid Beta Structures Drive Two Modes of Membrane-Mediated Toxicity

(2019) Crystal M. Vander Zanden et al.   LANGMUIR

Application of millisecond time-resolved solid state NMR to the kinetics and mechanism of melittin self-assembly

(2019) Jaekyun Jeon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid growth and membrane damage: Current themes and emerging perspectives from theory and experiments on Aβ and hIAPP

(2018) Michele F.M. Sciacca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The on-fibrillation-pathway membrane content leakage and off-fibrillation-pathway lipid mixing induced by 40-residue β-amyloid peptides in biologically relevant model liposomes

(2018) Qinghui Cheng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Interactions between amyloid β peptide and lipid membranes

(2018) Zheng Niu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Applications of dissolution dynamic nuclear polarization in chemistry and biochemistry

(2018) Guannan Zhang et al.   MAGNETIC RESONANCE IN CHEMISTRY

Effect of water/glycerol polymorphism on dynamic nuclear polarization

(2018) Alisa Leavesley et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Fast and accurate MAS–DNP simulations of large spin ensembles

(2017) Frédéric Mentink-Vigier et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Combining DNP NMR with segmental and specific labeling to study a yeast prion protein strain that is not parallel in-register

(2017) Kendra K. Frederick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic nuclear polarization for sensitivity enhancement in modern solid-state NMR

(2017) Aany Sofia Lilly Thankamony et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Amyloid-β adopts a conserved, partially folded structure upon binding to zwitterionic lipid bilayers prior to amyloid formation

(2016) Kyle J. Korshavn et al.   CHEMICAL COMMUNICATIONS

Distinct Membrane Disruption Pathways Are Induced by 40-Residue β-Amyloid Peptides

(2016) Dennis A. Delgado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient DNP NMR of membrane proteins: sample preparation protocols, sensitivity, and radical location

(2016) Shu Y. Liao et al.   JOURNAL OF BIOMOLECULAR NMR

Solid effect DNP polarization dynamics in a system of many spins

(2016) Daniel Wiśniewski et al.   JOURNAL OF MAGNETIC RESONANCE

Dynamic Nuclear Polarization enhanced NMR at 187 GHz/284 MHz using an Extended Interaction Klystron amplifier

(2016) Thomas F. Kemp et al.   JOURNAL OF MAGNETIC RESONANCE

Instrumentation for solid-state dynamic nuclear polarization with magic angle spinning NMR

(2016) Melanie Rosay et al.   JOURNAL OF MAGNETIC RESONANCE

Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril

(2016) Marielle Aulikki Wälti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Characterization of Fibrils from Recombinant Human Islet Amyloid Polypeptide by Solid-State NMR: The Central FGAILS Segment Is Part of the β-Sheet Core

(2016) Franziska Weirich et al.   PLoS One

Competition between Fibrillation and Induction of Vesicle Fusion for the Membrane-Associated 40-Residue β-Amyloid Peptides

(2015) Rumonat D. Akinlolu et al.   BIOCHEMISTRY

The ABC exporter MsbA probed by solid state NMR – challenges and opportunities

(2015) Hundeep Kaur et al.   BIOLOGICAL CHEMISTRY

Matrix-Free DNP-Enhanced NMR Spectroscopy of Liposomes Using a Lipid-Anchored Biradical

(2015) Carlos Fernández-de-Alba et al.   CHEMISTRY-A EUROPEAN JOURNAL

Assembling a Correctly Folded and Functional Heptahelical Membrane Protein by ProteinTrans-splicing

(2015) Michaela Mehler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Successive Stages of Amyloid-β Self-Assembly Characterized by Solid-State Nuclear Magnetic Resonance with Dynamic Nuclear Polarization

(2015) Alexey Potapov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nuclear depolarization and absolute sensitivity in magic-angle spinning cross effect dynamic nuclear polarization

(2015) Frédéric Mentink-Vigier et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Pushing NMR sensitivity limits using dynamic nuclear polarization with closed-loop cryogenic helium sample spinning

(2015) E. Bouleau et al.   Chemical Science

The Molecular Structure of Alzheimer β-Amyloid Fibrils Formed in the Presence of Phospholipid Vesicles

(2014) Zheng Niu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Method for Dynamic Nuclear Polarization Enhancement of Membrane Proteins

(2014) Adam N. Smith et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Evolution and Membrane Interaction of the 40-Residue β Amyloid Peptides: Differences in the Initial Proximity between Peptides and the Membrane Bilayer Studied by Solid-State Nuclear Magnetic Resonance Spectroscopy

(2014) Wei Qiang et al.   BIOCHEMISTRY

Dynamic Nuclear Polarization-Enhanced NMR on Aligned Lipid Bilayers at Ambient Temperature

(2014) Orawan Jakdetchai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Basis of the Green–Blue Color Switching in Proteorhodopsin as Determined by NMR Spectroscopy

(2014) Jiafei Mao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Improved Dynamic Nuclear Polarization Surface-Enhanced NMR Spectroscopy through Controlled Incorporation of Deuterated Functional Groups

(2013) Alexandre Zagdoun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic Nuclear Polarization NMR Spectroscopy: Revealing Multiple Conformations in Lipid-Anchored Peptide Vaccines

(2013) Eline J. Koers et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Efficient, Water-Soluble Polarizing Agents for Dynamic Nuclear Polarization at High Frequency

(2013) Claire Sauvée et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

(2013) Jun-Xia Lu et al.   CELL

Dynamic nuclear polarization-enhanced 13C NMR spectroscopy of static biological solids

(2013) Alexey Potapov et al.   JOURNAL OF MAGNETIC RESONANCE

Membrane-Anchored A  Accelerates Amyloid Formation and Exacerbates Amyloid-Associated Toxicity in Mice

(2013) A. Nagarathinam et al.   JOURNAL OF NEUROSCIENCE

Higher Order Amyloid Fibril Structure by MAS NMR and DNP Spectroscopy

(2013) Galia T. Debelouchina et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Influence of deuteration in the glassing matrix on 13C dynamic nuclear polarization

(2013) Lloyd Lumata et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Rapid Natural-Abundance 2D13C-13C Correlation Spectroscopy Using Dynamic Nuclear Polarization Enhanced Solid-State NMR and Matrix-Free Sample Preparation

(2012) Hiroki Takahashi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Theory for cross effect dynamic nuclear polarization under magic-angle spinning in solid state nuclear magnetic resonance: The importance of level crossings

(2012) Kent R. Thurber et al.   JOURNAL OF CHEMICAL PHYSICS

Helium-cooling and -spinning dynamic nuclear polarization for sensitivity-enhanced solid-state NMR at 14T and 30K

(2012) Yoh Matsuki et al.   JOURNAL OF MAGNETIC RESONANCE

Fast passage dynamic nuclear polarization on rotating solids

(2012) Frederic Mentink-Vigier et al.   JOURNAL OF MAGNETIC RESONANCE

Solid state nuclear magnetic resonance with magic-angle spinning and dynamic nuclear polarization below 25K

(2012) Kent R. Thurber et al.   JOURNAL OF MAGNETIC RESONANCE

Dynamic Nuclear Polarization NMR Spectroscopy of Microcrystalline Solids

(2012) Aaron J. Rossini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct three-dimensional visualization of membrane disruption by amyloid fibrils

(2012) L. Milanesi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiparallel  -sheet architecture in Iowa-mutant  -amyloid fibrils

(2012) W. Qiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fractional Spin-Labeling of Polymers for Enhancing NMR Sensitivity by Solvent-Free Dynamic Nuclear Polarization

(2011) Veronika Vitzthum et al.   CHEMPHYSCHEM

Membrane and surface interactions of Alzheimer’s Aβ peptide - insights into the mechanism of cytotoxicity

(2011) Thomas L. Williams et al.   FEBS Journal

Microwave field distribution in a magic angle spinning dynamic nuclear polarization NMR probe

(2011) Emilio A. Nanni et al.   JOURNAL OF MAGNETIC RESONANCE

Amyloid β Peptides Aggregation in a Mixed Membrane Bilayer: A Molecular Dynamics Study

(2011) Li Na Zhao et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Intermolecular Structure Determination of Amyloid Fibrils with Magic-Angle Spinning and Dynamic Nuclear Polarization NMR

(2011) Marvin J. Bayro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical Shifts for the Unusual DNA Structure in Pf1 Bacteriophage from Dynamic-Nuclear-Polarization-Enhanced Solid-State NMR Spectroscopy

(2011) Ivan V. Sergeyev et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New Structural Model of Aβ40Fibrils

(2011) Ivano Bertini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tumor imaging using hyperpolarized 13C magnetic resonance spectroscopy

(2011) Kevin M. Brindle et al.   MAGNETIC RESONANCE IN MEDICINE

Polymorphism of amyloid β peptide in different environments: implications for membrane insertion and pore formation

(2011) Fernando Terán Arce et al.   Soft Matter

Dynamic Nuclear Polarization of Deuterated Proteins

(2010) Ümit Akbey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Low-temperature dynamic nuclear polarization at 9.4T with a 30mW microwave source

(2010) Kent R. Thurber et al.   JOURNAL OF MAGNETIC RESONANCE

Dynamic nuclear polarization-enhanced solid-state NMR spectroscopy of GNNQQNY nanocrystals and amyloid fibrils

(2010) Galia T. Debelouchina et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

The interaction of beta-amyloid protein with cellular membranes stimulates its own production

(2009) Imke Peters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Functional and shunt states of bacteriorhodopsin resolved by 250 GHz dynamic nuclear polarization-enhanced solid-state NMR

(2009) V. S. Bajaj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metal effects on the membrane interactions of amyloid-β peptides

(2008) John D. Gehman et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Measurement of sample temperatures under magic-angle spinning from the chemical shift and spin-lattice relaxation rate of 79Br in KBr powder

(2008) Kent R. Thurber et al.   JOURNAL OF MAGNETIC RESONANCE

Amyloid-β Membrane Binding and Permeabilization are Distinct Processes Influenced Separately by Membrane Charge and Fluidity

(2008) Pamela T. Wong et al.   JOURNAL OF MOLECULAR BIOLOGY

Swept-frequency two-pulse phase modulation (SWf-TPPM) sequences with linear sweep profile for heteronuclear decoupling in solid-state NMR

(2008) C. Vinod Chandran et al.   MAGNETIC RESONANCE IN CHEMISTRY

Molecular structural basis for polymorphism in Alzheimer's  -amyloid fibrils

(2008) A. K. Paravastu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA