Article
Emergency Medicine
Tzu-Yun Liu, Ming-Ta Tsai, Fu-Cheng Chen, Hsiu-Yung Pan, Jyun-Bin Huang, Fu-Jen Cheng, Chi-Yung Cheng
Summary: This study evaluated the impact of CRS on patient disposition in the ED for symptoms suggestive of acute coronary syndrome. Results showed that patients in the CRS group had higher rates of direct ED discharge and lower rates of hospitalization and against-advice discharge.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Emergency Medicine
Ronald Check, Brian Kelly, Erica Dunn, Holly Stankewicz, Jenna Hakim, Kate Arner, Kylie Ridley, Jennifer Irick, Michael Irick, Darin Agresti, Rebecca Jeanmonod
Summary: The HEART score is a commonly used clinical decision tool for risk stratification in patients with chest pain. A retrospective cohort study found that younger age, female sex, and non-white race were independent predictors of not having the HEART score documented in patients with chest pain.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Medicine, General & Internal
Charles Reynard, Brian McMillan, Anisa Jafar, Anthony Heagerty, Glen Philip Martin, Evangelos Kontopantelis, Richard Body
Summary: This research aims to investigate the prognostic characteristics of routinely collected data in emergency departments for long-term cardiovascular disease outcomes using quantitative and qualitative methods. Approved by the Research Ethics Committee, the study findings will be disseminated through peer-review publications, conference presentations, and a public dissemination strategy.
Article
Cardiac & Cardiovascular Systems
Swaraj Nandini Pande, J. Yavana Suriya, Sachit Ganapathy, Ajith Ananthakrishna Pillai, Santhosh Satheesh, Nivedita Mondal, K. T. Harichandra Kumar, Candice Silversides, Samuel C. Siu, Rohan D'Souza, Anish Keepanasseril
Summary: This study aimed to validate and establish the clinical utility of two risk stratification tools (DEVI and CARPREG-II) for predicting adverse cardiac events in pregnant patients with valvular heart disease (VHD). The results showed that both tools had good discriminative ability and clinical utility across a range of probabilities. The DEVI score showed better agreement between predicted probabilities and observed events.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Linda S. B. Johnson, Jonas Oldgren, Tyler W. Barrett, Candace D. McNaughton, Jorge A. Wong, William F. McIntyre, Clifford L. Freeman, Laura Murphy, Gunnar Engstrom, Michael Ezekowitz, Stuart J. Connolly, Lizhen Xu, Juliet Nakamya, David Conen, Shrikant Bangdiwala, Salim Yusuf, Jeff S. Healey
Summary: This study focused on the risk of new-onset heart failure (HF) in atrial fibrillation (AF) patients after emergency department (ED) visits, and developed a scoring system named LVS-HARMED to predict the risk of HF within one year. The LVS-HARMED score showed good discrimination and can be a useful tool in identifying patients at high risk for HF.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Emergency Medicine
Mucahit Kesgun, Burcu Genc Yavuz, Dilay Satilmis, Sahin Colak
Summary: The study compares the TIMI score with the T-MACS score and concludes that the T-MACS score is more successful in determining low risk, high risk, and estimated 1-month MACE risk in patients with chest pain in the emergency department.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Sarah Cohen, Aihua Liu, Fei Wang, Liming Guo, James M. Brophy, Michal Abrahamowicz, Judith Therrien, Luc M. Beauchesne, Elisabeth Bedard, Jasmine Grewal, Paul Khairy, Erwin Oechslin, S. Lucy Roche, Candice K. Silversides, Isabelle F. Vonder Muhll, Ariane J. Marelli
Summary: The study aimed to develop a risk prediction system for HF hospitalization in ACHD patients and successfully identified high-risk patients using predictors such as age, sex, CHD lesion severity, recent HFH history, and comorbidities. The risk scoring system showed excellent prediction performance.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Review
Multidisciplinary Sciences
Jonathon Stewart, Juan Lu, Adrian Goudie, Mohammed Bennamoun, Peter Sprivulis, Frank Sanfillipo, Girish Dwivedi
Summary: This systematic review examined the application of machine learning in risk stratification for adults presenting to the emergency department with undifferentiated chest pain. The study found that ML models outperformed physicians and current risk stratification tools in diagnosing acute myocardial infarction and predicting major adverse cardiovascular events. However, integration of ML models into clinical practice remains limited.
Article
Cardiac & Cardiovascular Systems
Luke P. Dawson, Emily Nehme, Ziad Nehme, Esther Davis, Jason Bloom, Shelley Cox, Adam J. Nelson, Daniel Okyere, David Anderson, Michael Stephenson, Jeffrey Lefkovits, Andrew J. Taylor, Stephen J. Nicholls, Louise Cullen, David Kaye, Karen Smith, Dion Stub
Summary: This study aimed to assess sex differences in the epidemiology and care pathways of chest pain management. The study found significant discrepancies in care for women throughout the entire patient journey, and women had higher mortality for ST-segment elevation myocardial infarction but better outcomes for other etiologies of chest pain.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Emergency Medicine
Ziad Faramand, Christian Martin-Gill, Stephanie O. Frisch, Clifton Callaway, Salah Al-Zaiti
Summary: The study found that the HEART score performs poorly in risk stratifying patients with cocaine-associated chest pain, and is not recommended as a tool to identify those at low risk of major adverse cardiac events (MACE).
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shunsuke Tamaki, Takahisa Yamada, Tetsuya Watanabe, Takashi Morita, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Masahiro Seo, Jun Nakamura, Kiyomi Kayama, Daisuke Sakamoto, Kumpei Ueda, Takehiro Kogame, Yuto Tamura, Takeshi Fujita, Keisuke Nishigaki, Yuto Fukuda, Yuki Kokubu, Masatake Fukunami
Summary: This study validates the ability of the 2-year MIBG-based cardiac mortality risk model to predict post-discharge clinical outcomes in patients with ADHF, and compares its prognostic value with that of the ADHERE and GWTG-HF risk scores.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Emergency Medicine
Gurkan Akman, Nihat Mujdat Hokenek, Kaan Yusufoglu, Damla Akman, Orhan Hagi, Burcu Bayramoglu, Burcu Genc Yavuz, Sahin Colak
Summary: This study evaluated the ability of the HEART and T-MACS scores to predict major cardiac events (MACE) in emergency department patients with chest pain. The results showed that the T-MACS score was more accurate than the HEART score in predicting low risk, high risk, and one-month risk for MACE.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2023)
Article
Medicine, General & Internal
Essa Tawfiq, Vanessa Selak, Mark Elwood, Romana Pylypchuk, Sandar Tin Tin, Matire Harwood, Corina Grey, Mark McKeage, Sue Wells
Summary: In this study, researchers assessed the performance of cardiovascular disease risk prediction equations in survivors of cancer in New Zealand. The study found that these equations reasonably predicted the 5-year cardiovascular disease risk in survivors and suggested their use for risk assessment in this population.
Article
Medicine, General & Internal
Chunpeng Ma, Xiaoli Liu, Lixiang Ma
Summary: A new risk score has been developed for assessing the risk of acute chest pain patients without known coronary artery disease and ST-segment deviation, and with normal high-sensitivity troponin I levels, aiding in the assessment of major adverse cardiac events risk and patient triage in the emergency department.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Gregory Y. H. Lip, Richard R. Murphy, Farhad Sahiar, Timothy J. Ingall, Amol D. Dhamane, Mauricio Ferri, Patrick Hlavacek, Madison T. Preib, Allison Keshishian, Cristina Russ, Lisa Rosenblatt, Huseyin Yuce, Steven Deitelzweig
Summary: This study evaluated the incidence of adverse outcomes among patients with nonvalvular atrial fibrillation receiving oral anticoagulants based on the CHA(2)DS(2)-VASc risk score, thromboembolic event history, and age group. The results provide insights into the importance of specific risk score range, thromboembolic event history, and age group strata in clinical decision-making, research, and policy.
Article
Pediatrics
Priya M. Kevat, Ronny Gunnarsson, Benjamin M. Reeves, Alan R. Ruben
Summary: The study aimed to determine adherence rates of secondary prophylaxis with benzathine penicillin G injections in a pediatric population in Far North Queensland and identify factors contributing to suboptimal adherence. Results showed very low adherence to the recommended injection intervals, with factors such as age and year of inclusion affecting delivery. Interventions should target individual factors to improve timely delivery of secondary prophylaxis for ARF and RHD.
JOURNAL OF PAEDIATRICS AND CHILD HEALTH
(2021)
Article
Parasitology
Benjamin F. R. Dickson, Patricia M. Graves, Ni Ni Aye, Thet Wai Nwe, Tint Wai, San San Win, Myint Shwe, Janet Douglass, Peter Wood, Kinley Wangdi, William J. McBride
Summary: This study examined factors associated with persistent infection, LF-related hydrocoele, and MDA participation. Results showed that being CFA positive was associated with age, male gender, elevation, and household population density; LF-related hydrocoele was associated with age and residing in Amarapura Township; never taking MDA was associated with male gender and age.
PARASITES & VECTORS
(2021)
Article
Public, Environmental & Occupational Health
Elizabeth Maulingin-Gumbaketi, Sarah Larkins, Ronny Gunnarsson, Gun Rembeck, Maxine Whittaker, Michelle Redman-MacLaren
Summary: This study in Papua New Guinea explores post-menarcheal women's understanding of body changes and menarche, preparation for menarche, and related cultural beliefs and practices. The findings suggest that limited pre-menarcheal awareness of the meaning of body changes and menarche is linked to a culture of shame and secrecy about open discussion on sexuality. Traditional cultural practices, however, provide an opportunity for collective support and focused learning for girls.
Review
Medicine, General & Internal
Stefan Malmberg, Susanna Petren, Ronny Gunnarsson, Katarina Hedin, Paer-Daniel Sundvall
Summary: The findings suggest that FN may be involved in acute sore throat in PHC patients, but the association is much weaker compared to GAS.
Article
Surgery
Adam T. Cristaudo, Kerry Hitos, Ronny Gunnarsson, Alan Decosta
Summary: This study aimed to develop and validate a multivariable prediction model for entero-atmospheric fistula (EAF) and constructed an easy-to-use probability nomogram based on two predictor variables.
ANZ JOURNAL OF SURGERY
(2022)
Article
Medicine, General & Internal
Esther A. R. Hartman, Wim G. Groen, Silje Rebekka Heltveit-Olsen, Morten Lindbaek, Sigurd Hoye, Par-Daniel Sundvall, Ronny Gunnarsson, Ingmarie Skoglund, Egill Snaebjornsson Arnljots, Maciej Godycki-Cwirko, Anna Kowalczyk, Tamara N. Platteel, Nicolaas P. A. Zuithoff, Annelie A. Monnier, Theo J. M. Verheij, Cees M. P. M. Hertogh, Alma C. van de Pol
Summary: This study aims to reduce inappropriate antibiotic use for urinary tract infections in frail elderly through an antibiotic stewardship intervention. The research includes qualitative study, pragmatic cluster randomised controlled trial, implementation of a multifaceted ASI, and the use of modified participatory-action-research approach for implementation.
Article
Medicine, General & Internal
Ronny Gunnarsson, Ulrich Orda, Bradley Elliott, Clare Heal, Chris Del Mar
Summary: POCT can reduce the risk of GABHS infection in high-risk ARF patients and unnecessary antibiotic prescriptions. For low-risk patients, antibiotics should only be considered with high pain levels, high Centor scores, and positive GABHS results from POCT, to minimize unnecessary testing and antibiotic use.
Review
Public, Environmental & Occupational Health
Elizabeth Maulingin-Gumbaketi, Sarah Larkins, Maxine Whittaker, Gun Rembeck, Ronny Gunnarsson, Michelle Redman-MacLaren
Summary: This paper reviews the social and cultural factors that affect women's ability to effectively manage their menstrual health and hygiene (MHH) in Pacific Island Countries and Territories (PICTs). The review found that the MHH experiences of women in PICTs are shaped by socio-cultural norms and practices. These norms and practices need to be incorporated into sexual and reproductive health planning, programs, and education to be relevant to diverse village and urban settings in PICTs.
REPRODUCTIVE HEALTH
(2022)
Article
Infectious Diseases
Stefan Malmberg, Taha Khan, Ronny Gunnarsson, Gunnar Jacobsson, Par-Daniel Sundvall
Summary: This study evaluated a new camera-based non-contact method for rapid measurement of vital signs such as heart rate, blood oxygen saturation, respiratory rate, and blood pressure. The results showed that although the measurements were close to the gold standard, there was higher random variation, indicating the need for technical improvements.
INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
Silje Rebekka Heltveit-Olsen, Par-Daniel Sundvall, Ronny Gunnarsson, Egill Snaebjornsson Arnljots, Anna Kowalczyk, Maciek Godycki-Cwirko, Tamara N. Platteel, Hilde A. M. Koning, Wim G. Groen, Christina Ahren, Nils Grude, Theo J. M. Verheij, Cees M. P. M. Hertogh, Morten Lindbaek, Sigurd Hoye
Summary: This study aims to assess whether Methenamine hippurate can reduce the incidence of UTIs in older women with recurrent UTIs through a randomized, controlled, triple-blind phase IV clinical trial. The results will be disseminated in peer-reviewed journals and scientific conferences after obtaining ethical approvals in all participating countries.
Article
Public, Environmental & Occupational Health
Lena Rindner, Lena Nordeman, Gunilla Stroemme, Dominique Hange, Ronny Gunnarsson, Gun Rembeck
Summary: This study evaluates the effect of group education and person-centered individual support in primary health care (PHC) on the mental health and quality of life of menopausal women. The results show that these interventions can improve quality of life and reduce menopause-related symptoms in the short term, with lasting effects and potential prevention of exhaustion syndrome.
Article
Medicine, General & Internal
Esther A. R. Hartman, Alma C. van de Pol, Silje Rebekka Heltveit-Olsen, Morten Lindbaek, Sigurd Hoye, Sara Sofia Lithen, Par-Daniel Sundvall, Sofia Sundvall, Egill Snaebjornsson Arnljots, Ronny Gunnarsson, Anna Kowalczyk, Maciek Godycki-Cwirko, Tamara N. Platteel, Wim G. Groen, Annelie A. Monnier, Nicolaas P. Zuithoff, Theo J. M. Verheij, Cees M. P. M. Hertogh
Summary: A multifaceted antibiotic stewardship intervention effectively reduced antibiotic prescribing for suspected urinary tract infections in frail older adults.
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Letter
Infectious Diseases
Ronny K. Gunnarsson, Mark Ebell, Robert Centor, Paul Little, Theo Verheij, Morten Lindbaek, Par-Daniel Sundvall
INFECTIOUS DISEASES
(2023)
Article
Infectious Diseases
Ronny K. Gunnarsson, Mark Ebell, Robert Centor, Paul Little, Theo Verheij, Morten Lindbaek, Paer-Daniel Sundvall
Summary: Experts from different countries have reached a consensus on the management of patients with acute sore throat by introducing a new triage scheme that considers both short-term and long-term risks. The article also explores the emerging trend of nurses and pharmacists independently managing these patients and the need for safety netting in such practice.
INFECTIOUS DISEASES
(2023)
Article
Health Care Sciences & Services
Karin Rystedt, Katarina Hedin, Mia Tyrstrup, Gunilla Skoog-Stahlgren, Charlotta Edlund, Christian G. Giske, Ronny Gunnarsson, Paer-Daniel Sundvall
Summary: The aim of this study was to compare the effectiveness of rapid antigen detection test (RADT) and throat culture for group A streptococci (GAS) among patients recently treated with penicillin V. The results showed 91% agreement between RADT and culture at a follow-up visit within 21 days. The study concludes that RADT carries a low risk of missing the presence of GAS.
SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE
(2023)