Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage

ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination

(2019) Guangming Ren et al.   EMBO JOURNAL

Pyramidal cell regulation of interneuron survival sculpts cortical networks

(2018) Fong Kuan Wong et al.   NATURE

Characterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization

(2017) Jr-M Yang et al.   ONCOGENE

PTEN: Local and Global Modulation of Neuronal Function in Health and Disease

(2017) Shira Knafo et al.   TRENDS IN NEUROSCIENCES

Tanshinone I alleviates motor and cognitive impairments via suppressing oxidative stress in the neonatal rats after hypoxic-ischemic brain damage

(2017) Chunfang Dai et al.   Molecular Brain

Propofol Prevents Hippocampal Neuronal Loss and Memory Impairment in Cerebral Ischemia Injury Through Promoting PTEN Degradation

(2016) Xin Chen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

PTEN recruitment controls synaptic and cognitive function in Alzheimer's models

(2016) Shira Knafo et al.   NATURE NEUROSCIENCE

ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells

(2015) Jing-Hong Chen et al.   Autophagy

Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis

(2014) Zhifang Dong et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular and phenotypic abnormalities in individuals with germline heterozygous PTEN mutations and autism

(2014) T W Frazier et al.   MOLECULAR PSYCHIATRY

Rab5 and Ndfip1 Are Involved in Pten Ubiquitination and Nuclear Trafficking

(2014) Yijia Li et al.   TRAFFIC

p34 is a novel regulator of the oncogenic behavior of NEDD4-1 and PTEN

(2013) S-W Hong et al.   CELL DEATH AND DIFFERENTIATION

Nuclear trafficking of Pten after brain injury leads to neuron survival not death

(2013) Choo-Peng Goh et al.   EXPERIMENTAL NEUROLOGY

Critical Role of Increased PTEN Nuclear Translocation in Excitotoxic and Ischemic Neuronal Injuries

(2013) S. Zhang et al.   JOURNAL OF NEUROSCIENCE

PTEN inhibition prevents rat cortical neuron injury after hypoxia–ischemia

(2013) J. Zhao et al.   NEUROSCIENCE

Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia

(2012) Jason Howitt et al.   JOURNAL OF CELL BIOLOGY

Regulation of nuclear TDP-43 by NR2A-containing NMDA receptors and PTEN

(2012) M. Zheng et al.   JOURNAL OF CELL SCIENCE

Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma

(2012) Elizabeth Pohler et al.   NATURE GENETICS

The functions and regulation of the PTEN tumour suppressor

(2012) Min Sup Song et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Childhood Outcomes after Hypothermia for Neonatal Encephalopathy

(2012) Seetha Shankaran et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Tumor Suppressor PTEN Is Exported in Exosomes and Has Phosphatase Activity in Recipient Cells

(2012) U. Putz et al.   Science Signaling

Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner

(2011) Min Sup Song et al.   CELL

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

(2011) Fang Sun et al.   NATURE

Predicting motor outcome and death in term hypoxic-ischemic encephalopathy

(2011) M. Martinez-Biarge et al.   NEUROLOGY

Stroke intervention pathways: NMDA receptors and beyond

(2011) Ted Weita Lai et al.   TRENDS IN MOLECULAR MEDICINE

Epidemiology of neonatal encephalopathy and hypoxic–ischaemic encephalopathy

(2010) Jennifer J. Kurinczuk et al.   EARLY HUMAN DEVELOPMENT

E3 Ligase Nedd4 Promotes Axon Branching by Downregulating PTEN

(2010) Jovana Drinjakovic et al.   NEURON

Hippocampal long-term depression is required for the consolidation of spatial memory

(2010) Y. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of the PTEN–AKT–FOXO3a Pathway in Neuronal Apoptosis in Developing Rat Brain after Hypoxia–Ischemia

(2009) Deyuan Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A systematic review of the role of intrapartum hypoxia-ischemia in the causation of neonatal encephalopathy

(2008) Ernest M. Graham et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Crucial role of the C-terminus of PTEN in antagonizing NEDD4-1-mediated PTEN ubiquitination and degradation

(2008) Xinjiang Wang et al.   BIOCHEMICAL JOURNAL

A new penumbra: transitioning from injury into repair after stroke

(2008) Eng H Lo   NATURE MEDICINE