Article
Health Care Sciences & Services
Adila Awaludin, Cherry Rahayu, Nur Aizati Athirah Daud, Neily Zakiyah
Summary: This systematic review assessed the efficacy and safety of antihypertensive drugs in severe hypertension during pregnancy. The results showed that several drugs, including nifedipine and labetalol, can be used for the treatment of severe hypertension in pregnancy. There was no difference in the risk of maternal hypotension, maternal and fetal outcomes, and adverse effects between the drugs, except for dihydralazine and ketanserin, which had more adverse effects.
Article
Health Care Sciences & Services
Junjun Chen, Yuelong Ji, Tao Su, Ma Jin, Zhichao Yuan, Yuanzhou Peng, Shuang Zhou, Heling Bao, Shusheng Luo, Hui Wang, Jue Liu, Na Han, Hai-Jun Wang
Summary: Prediction models developed through machine learning statistics can help identify high-risk patients with de novo hypertensive disorder of pregnancy, enabling timely intervention and care.
Article
Obstetrics & Gynecology
Hua Zen Ling, Gavin Guy, Kypros H. Nicolaides, Nikos A. Kametas
Summary: This study aimed to assess the maternal cardiac adaptation in normotensive and hypertensive pregnancies and control for important maternal characteristics. The results showed that women with preeclampsia and gestational hypertension had abnormal cardiac adaptation compared to normotensive women. This abnormality was evident after 20 weeks of gestation and at least 10 weeks before the clinical manifestation of the disease.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Cardiac & Cardiovascular Systems
Veronica Giorgione, Asma Khalil, Jamie O'Driscoll, Basky Thilaganathan
Summary: This study assessed the effectiveness of peripartum screening in predicting CHT after HDP and found that a prediction model combining clinical and echocardiographic features showed excellent accuracy in identifying women at risk of persistent hypertension after HDP.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Environmental Sciences
Emma Preston, Marie-France Hivert, Abby F. Fleisch, Antonia M. Calafat, Sharon K. Sagiv, Wei Perng, Sheryl L. Rifas-Shiman, Jorge E. Chavarro, Emily Oken, Ami R. Zota, Tamarra James-Todd
Summary: This study found that exposure to certain PFAS may increase the risk of gestational hypertension during pregnancy, with potential implications for maternal and child health outcomes.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Immunology
Daniella Frances Susic, Leanne Wang, Lynne Margaret Roberts, Michelle Bai, Andrew Gia, Emily McGovern, Xiao-Tao Jiang, Gregory K. Davis, Emad El-Omar, Amanda Henry
Summary: This study found that hypertension during pregnancy may have an impact on the postpartum microbiota of mothers and infants. Although the sample size was small, these preliminary findings provide important insights for further research and contribute to understanding the changes in the microbiota of offspring from women with hypertensive disorders of pregnancy and their possible association with cardiovascular disease.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Nutrition & Dietetics
Minerva J. Taeubert, Clarissa J. Wiertsema, Marijn J. Vermeulen, Hugo G. Quezada-Pinedo, Irwin K. Reiss, Martina U. Muckenthaler, Romy Gaillard
Summary: The study found that higher maternal early pregnancy serum ferritin concentrations were associated with higher systolic and diastolic blood pressure throughout pregnancy. After adjustment, only higher early pregnancy serum ferritin concentrations were associated with higher early pregnancy diastolic blood pressure and a higher mid pregnancy umbilical artery pulsatility index.
JOURNAL OF NUTRITION
(2022)
Article
Multidisciplinary Sciences
Birhanu Jikamo, Mulat Adefris, Telake Azale, Kassahun Alemu
Summary: This study aimed to assess the impact of preeclampsia on adverse maternal outcomes and identify risk factors among women with preeclampsia in the Sidama region. The results showed that women with preeclampsia had a higher risk of adverse maternal outcomes, especially those with severe features of preeclampsia.
SCIENTIFIC REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Julian E. Garcia, Ian R. Mulrenin, Anh B. Nguyen, Matthew S. Loop, Melissa A. Daubert, Rachel Urrutia, Craig R. Lee
Summary: Hypertensive disorders of pregnancy (HDP) are becoming more common and have negative effects on both mothers and infants. Labetalol, nifedipine, and methyldopa are recommended as the first-line medications for HDP treatment. However, the actual usage and selection of antihypertensive drugs remains unclear. A retrospective cohort study involving 1,641 HDP patients was conducted, and it was found that 77.8% of patients used antihypertensive medications. Labetalol was the most commonly used medication, followed by nifedipine and hydralazine. The severity of HDP was associated with a higher likelihood of antihypertensive use. Further research comparing medication effectiveness in different types of HDP is needed.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Elisa Montaguti, Gaetana Di Donna, Aly Youssef, Gianluigi Pilu
Summary: Hypertensive disorders, including preeclampsia, are common in pregnancies and can have long-term cardiovascular consequences. Preeclampsia may not solely be caused by placental dysfunction, but also by maternal cardiovascular system failure to adapt to pregnancy. Evaluating maternal hemodynamic variables is important in identifying high-risk women and implementing appropriate prophylaxis.
JOURNAL OF MEDICAL ULTRASONICS
(2022)
Article
Cardiac & Cardiovascular Systems
Jennifer J. Stuart, Lauren J. Tanz, Eric B. Rimm, Donna Spiegelman, Stacey A. Missmer, Kenneth J. Mukamal, Kathryn M. Rexrode, Janet W. Rich-Edwards
Summary: This study aimed to evaluate the association between hypertensive disorders of pregnancy (HDP) and long-term cardiovascular disease (CVD) and identify the proportion mediated by established CVD risk factors. The results showed that women with HDP during their first pregnancy had a higher risk of CVD, which was mainly mediated by established CVD risk factors.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Peripheral Vascular Disease
Laura A. Magee, Jeffrey Bone, Salwa Banoo Owasil, Joel Singer, Terry Lee, Mrutunjaya B. Bellad, Shivaprasad S. Goudar, Alexander G. Logan, Salesio E. Macuacua, Ashalata A. Mallapur, Hannah L. Nathan, Rahat N. Qureshi, Esperanca Sevene, Andrew H. Shennan, Anifa Vala, Marianne Vidler, Zulfiqar A. Bhutta, Peter von Dadelszen
Summary: In pregnancy, higher blood pressure levels and visit-to-visit variability are associated with adverse pregnancy outcomes, with each 5 mm Hg increase in blood pressure levels leading to increased odds of the composite outcome. Increased blood pressure visit-to-visit variability is also associated with increased odds of hypertension and adverse pregnancy outcomes.
Review
Cardiac & Cardiovascular Systems
Kosar Gholami, Narges Norouzkhani, Meraj Kargar, Hamidreza Ghasemirad, Atieh Jafarabadi Ashtiani, Shamim Kiani, Mahdi Sajedi Far, Maryam Dianati, Yasaman Salimi, Amirmohammad Khalaji, Sara Honari, Niloofar Deravi
Summary: The aim of this study was to investigate the effect of interventional educations on the knowledge of pregnant women about hypertensive disorders of pregnancy (HDP). The study found that educational interventions can improve pregnant women's knowledge about HDP, thereby reducing the occurrence of related complications.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Obstetrics & Gynecology
Matthew P. Brohan, Fionn P. Daly, Louise Kelly, Fergus P. Mccarthy, Ali S. Khashan, Karolina Kublickiene, Peter M. Barrett
Summary: This systematic review examines the association between hypertensive disorders of pregnancy and the long-term risk for maternal stroke. The results show that exposure to hypertensive disorders of pregnancy, particularly preeclampsia and gestational hypertension, is associated with an increased risk for any stroke and ischemic stroke among parous patients in later life.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Review
Environmental Sciences
Abigail Erinc, Melinda B. Davis, Vasantha Padmanabhan, Elizabeth Langen, Jaclyn M. Goodrich
Summary: Studies suggest that PFAS may be risk factors for HDP, showing associations, but more research is needed to further understand this link.
ENVIRONMENTAL RESEARCH
(2021)
Article
Health Care Sciences & Services
Wendy Tong, Supriya Kapur, Alexa Fleet, Samantha Russo, Apurva Khedagi, Craig D. Blinderman, Shunichi Nakagawa
Summary: This qualitative study examined the experiences of remote volunteer palliative care consultants during the initial COVID-19 surge. The study identified several themes, including motivations for participating, logistical evaluation of the program, barriers to care delivery, emotional burden, and ideas for improvements. Overall, participants had positive experiences and provided recommendations for future programs.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2022)
Article
Medicine, General & Internal
Sherif M. Shoucri, Lawrence Purpura, Clare DeLaurentis, Matthew A. Adan, Deborah A. Theodore, Alexandria Lauren Irace, Shelief Y. Robbins-Juarez, Apurva M. Khedagi, Daniel Letchford, Amro A. Harb, Lillian M. Zerihun, Kate E. Lee, Karen Gambina, Max C. Lauring, Noah Chen, Colin P. Sperring, Sanket S. Mehta, Ellen L. Myers, Hueyjong Shih, Michael G. Argenziano, Samuel L. Bruce, Cody L. Slater, Jonathan R. Tiao, Karthik Natarajan, George Hripcsak, Ruijun Chen, Michael T. Yin, Magdalena E. Sobieszczyk, Delivette Castor, Jason E. Zucker
Summary: Patients hospitalized with SARS-CoV-2 infection reported persistent symptoms up to 6 months after diagnosis, with cardiopulmonary symptoms and generalized or neuropsychiatric symptoms increasing over time. Severe COVID-19 patients were more likely to experience reduced mobility, decreased independence, or new dialysis requirements in the 6 months following hospitalization.
Review
Cardiac & Cardiovascular Systems
Apurva Khedagi, Cara Hoke, Michelle Kelsey, Andrea Coviello, W. Schuyler Jones, Larry R. Jackson II, Manesh R. Patel, Rob W. McGarrah, Neha J. Pagidipati, Nishant P. Shah
Summary: Cardiovascular disease remains a major global health issue and disproportionately affects certain communities. Disparities in the use and distribution of SGLT-2 inhibitors and GLP-1 agonists contribute to unequal cardiovascular outcomes. This review aims to understand and address these differences to reduce disparities in cardiovascular morbidity and mortality due to race, sex, and income inequality.
AMERICAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Education, Scientific Disciplines
Deepthiman Gowda, Tayla Curran, Apurva Khedagi, Michael Mangold, Faiz Jiwani, Urmi Desai, Rita Charon, Dorene Balmer
PERSPECTIVES ON MEDICAL EDUCATION
(2019)
Article
Cardiac & Cardiovascular Systems
Sukhjinder Singh Nijjer
CARDIOLOGY CLINICS
(2024)
Article
Cardiac & Cardiovascular Systems
Doosup Shin, Seung Hun Lee, David Hong, Ki Hong Choi, Joo Myung Lee
Summary: Post-PCI physiologic assessment has significant prognostic value and plays a role in functionally optimized PCI. Investigating the reasons behind suboptimal post-PCI physiologic results using pressure-wire pullback tracings and/or intravascular imaging is important. Functionally optimized PCI should be considered at the beginning of the procedure, and careful PCI planning using pre-PCI physiologic evaluation can increase the probability of achieving it.
CARDIOLOGY CLINICS
(2024)
Article
Cardiac & Cardiovascular Systems
Sonal Pruthi, Emaad Siddiqui, Nathaniel R. Smilowitz
CARDIOLOGY CLINICS
(2024)
Review
Cardiac & Cardiovascular Systems
Robert D. Safian
CARDIOLOGY CLINICS
(2024)
Article
Cardiac & Cardiovascular Systems
Adam Bland, Eunice Chuah, William Meere, Thomas J. Ford
Summary: CMD remains a challenging condition to manage due to its heterogeneous pathophysiology, presentation, and response to therapy. Awareness of CMD is improving, but there is a lack of randomized trials for therapy. Invasive assessment of the coronary microcirculation can improve patient-centered outcomes. Beta-blockers are still the cornerstone of therapy for angina due to CMD, while non-pharmacological interventions play a central role in management.
CARDIOLOGY CLINICS
(2024)
Article
Cardiac & Cardiovascular Systems
Samer Fawaz, Christopher M. Cook
CARDIOLOGY CLINICS
(2024)
Article
Cardiac & Cardiovascular Systems
Nils P. Johnson
Summary: From the four recent RCTs on FFR published or presented in 2021, we have learned several important lessons: study design should focus on discordant decisions; composite endpoints for PCI should prioritize vessel-level outcomes over mortality; initial PCI must be considered when calculating the total amount of TVR; ultrahigh rates of FFR<0.8 do not influence treatment decisions based on angiography; and although PCI is a reasonable option, CABG yields better outcomes for patients with severe multivessel disease.
CARDIOLOGY CLINICS
(2024)
Article
Cardiac & Cardiovascular Systems
Tobin Joseph, Michael Foley, Rasha Al-Lamee
CARDIOLOGY CLINICS
(2024)
Article
Cardiac & Cardiovascular Systems
David M. Tehrani, Arnold H. Seto
Summary: Accurate interpretation of hemodynamic indices like FFR and NHPRs is crucial with their increasing use. The choice between FFR and NHPRs depends on specific clinical and procedural scenarios, and data on their use in special clinical situations is limited.
CARDIOLOGY CLINICS
(2024)
