Identified lung adenocarcinoma metabolic phenotypes and their association with tumor immune microenvironment

Immune cell infiltration-based signature for prognosis and immunogenomic analysis in breast cancer

(2020) Shiyuan Wang et al.   BRIEFINGS IN BIOINFORMATICS

Lung Cancer 2020

(2020) Brett C. Bade et al.   CLINICS IN CHEST MEDICINE

Competitive glucose metabolism as a target to boost bladder cancer immunotherapy

(2020) Julieta Afonso et al.   Nature Reviews Urology

Resistance to Checkpoint Inhibition in Cancer Immunotherapy

(2020) Luisa Barrueto et al.   Translational Oncology

Principles of Immunotherapy in Non-Small Cell Lung Cancer

(2020) Melinda L. Hsu et al.   Thoracic Surgery Clinics

Development and validation of an immune‐related prognostic signature in lung adenocarcinoma

(2020) Sijin Sun et al.   Cancer Medicine

Microenvironment characterization and multi-omics signatures related to prognosis and immunotherapy response of hepatocellular carcinoma

(2020) Furong Liu et al.   Experimental Hematology & Oncology

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

(2019) Jérôme Galon et al.   NATURE REVIEWS DRUG DISCOVERY

Navigating metabolic pathways to enhance antitumour immunity and immunotherapy

(2019) Xiaoyun Li et al.   Nature Reviews Clinical Oncology

The influence of microenvironment on tumor immunotherapy

(2019) Jieying Zhang et al.   FEBS Journal

Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence

(2019) Michal Harel et al.   CELL

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

(2018) Tina Cascone et al.   Cell Metabolism

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

(2018) Peng Jiang et al.   NATURE MEDICINE

Wild-type IDH2 promotes the Warburg effect and tumor growth through HIF1α in lung cancer

(2018) Jiangjiang Li et al.   Theranostics

Identification of an eight-gene prognostic signature for lung adenocarcinoma

(2018) Shicheng Li et al.   Cancer Management and Research

Altered cancer metabolism in mechanisms of immunotherapy resistance

(2018) Rishab Ramapriyan et al.   PHARMACOLOGY & THERAPEUTICS

IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade

(2017) Mark Ayers et al.   JOURNAL OF CLINICAL INVESTIGATION

Lung Adenocarcinoma and Squamous Cell Carcinoma Gene Expression Subtypes Demonstrate Significant Differences in Tumor Immune Landscape

(2017) Hawazin Faruki et al.   Journal of Thoracic Oncology

Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy

(2017) Teresa Davoli et al.   SCIENCE

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

(2017) Pornpimol Charoentong et al.   Cell Reports

Immune infiltration of tumor microenvironment following immunotherapy for glioblastoma multiforme

(2017) Giannis Sokratous et al.   Human Vaccines & Immunotherapeutics

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial

(2016) Roy S Herbst et al.   LANCET

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

(2015) Ping-Chih Ho et al.   CELL

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer

(2015) Hossein Borghaei et al.   NEW ENGLAND JOURNAL OF MEDICINE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors

(2012) Hélène Salmon et al.   JOURNAL OF CLINICAL INVESTIGATION

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

pROC: an open-source package for R and S+ to analyze and compare ROC curves

(2011) Xavier Robin et al.   BMC BIOINFORMATICS

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

(2011) Richard Possemato et al.   NATURE

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Immunotherapy for Lung Cancer

(2010) Penelope A. Bradbury et al.   Journal of Thoracic Oncology