Genome-wide genetic links between amyotrophic lateral sclerosis and autoimmune diseases

C9orf72 Intermediate Alleles in Patients with Amyotrophic Lateral Sclerosis, Systemic Lupus Erythematosus, and Rheumatoid Arthritis

(2019) Micaela Fredi et al.   NEUROMOLECULAR MEDICINE

Immune dysregulation in amyotrophic lateral sclerosis: mechanisms and emerging therapies

(2019) David R Beers et al.   LANCET NEUROLOGY

The Gut-Brain Axis in Neurodegenerative Diseases and Relevance of the Canine Model: A Review

(2019) Yoko M. Ambrosini et al.   Frontiers in Aging Neuroscience

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

(2019)   SCIENCE

Causal association of type 2 diabetes with amyotrophic lateral sclerosis: new evidence from Mendelian randomization using GWAS summary statistics

(2019) Ping Zeng et al.   BMC Medicine

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

(2019) Mike A Nalls et al.   LANCET NEUROLOGY

Rab GTPases and Membrane Trafficking in Neurodegeneration

(2018) Ferdi Ridvan Kiral et al.   CURRENT BIOLOGY

Inflammation in CNS neurodegenerative diseases

(2018) Jodie Stephenson et al.   IMMUNOLOGY

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

(2018) Aude Nicolas et al.   NEURON

Redox metals homeostasis in multiple sclerosis and amyotrophic lateral sclerosis: a review

(2018) Sahar Sheykhansari et al.   Cell Death & Disease

Neuroinflammatory mechanisms in amyotrophic lateral sclerosis pathogenesis

(2018) Jason R. Thonhoff et al.   CURRENT OPINION IN NEUROLOGY

Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs

(2018) Manoj Kumar Jaiswal   MEDICINAL RESEARCH REVIEWS

Loss of the Spinocerebellar Ataxia type 3 disease protein ATXN3 alters transcription of multiple signal transduction pathways

(2018) Li Zeng et al.   PLoS One

Ionic Homeostasis Maintenance in ALS: Focus on New Therapeutic Targets

(2018) Rossana Sirabella et al.   Frontiers in Neuroscience

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study

(2018) Nick Shrine et al.   Lancet Respiratory Medicine

No association between gluten sensitivity and amyotrophic lateral sclerosis

(2017) Anne E. Visser et al.   JOURNAL OF NEUROLOGY

Amyotrophic lateral sclerosis

(2017) Michael A van Es et al.   LANCET

Microbiology: Gut microbes augment neurodegeneration

(2017) Daniel Erny et al.   NATURE

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

(2017) Katrina M de Lange et al.   NATURE GENETICS

Gut microbiota and IBD: causation or correlation?

(2017) Josephine Ni et al.   Nature Reviews Gastroenterology & Hepatology

Amyotrophic Lateral Sclerosis

(2017) Robert H. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis

(2017) Beben Benyamin et al.   Nature Communications

Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes

(2017) Weihua Zhao et al.   JAMA Neurology

GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells

(2016) Zi-Jian Lan et al.   BREAST CANCER RESEARCH AND TREATMENT

Population-based risks for cancer in patients with ALS

(2016) Summer B. Gibson et al.   NEUROLOGY

How neuroinflammation contributes to neurodegeneration

(2016) R. M. Ransohoff   SCIENCE

Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease

(2016) Aaron Burberry et al.   Science Translational Medicine

Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease

(2016) Jennifer S. Yokoyama et al.   JAMA Neurology

Association between diabetes and amyotrophic lateral sclerosis in Sweden

(2015) D. Mariosa et al.   EUROPEAN JOURNAL OF NEUROLOGY

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

(2015) Jimmy Z Liu et al.   NATURE GENETICS

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

(2015) James Bentham et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Transglutaminase 6 Antibodies in the Serum of Patients With Amyotrophic Lateral Sclerosis

(2015) Avi Gadoth et al.   JAMA Neurology

Diabetes Mellitus, Obesity, and Diagnosis of Amyotrophic Lateral Sclerosis

(2015) Marianthi-Anna Kioumourtzoglou et al.   JAMA Neurology

Golgi fragmentation in amyotrophic lateral sclerosis, an overview of possible triggers and consequences

(2015) Vinod Sundaramoorthy et al.   Frontiers in Neuroscience

Genetic variability in the regulation of gene expression in ten regions of the human brain

(2014) Adaikalavan Ramasamy et al.   NATURE NEUROSCIENCE

Inflammatory bowel disease and celiac disease: Overlaps and differences

(2014) Virginia Pascual   WORLD JOURNAL OF GASTROENTEROLOGY

Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors

(2013) Ole A. Andreassen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosis

(2013) Julie D. Atkin et al.   JOURNAL OF NEUROCHEMISTRY

Immune-mediated Mechanisms in the Pathoprogression of Amyotrophic Lateral Sclerosis

(2013) Weihua Zhao et al.   Journal of Neuroimmune Pharmacology

ITIH4 and Gpx3 are potential biomarkers for amyotrophic lateral sclerosis

(2013) Hirotaka Tanaka et al.   JOURNAL OF NEUROLOGY

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Autoimmune disease preceding amyotrophic lateral sclerosis: An epidemiologic study

(2013) M. R. Turner et al.   NEUROLOGY

All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs

(2013) Andrew J. Schork et al.   PLoS Genetics

Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate

(2013) Ole A. Andreassen et al.   PLoS Genetics

Membrane trafficking in neuronal maintenance and degeneration

(2012) Dong Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

(2012) Lam C Tsoi et al.   NATURE GENETICS

Association of Long ATXN2 CAG Repeat Sizes With Increased Risk of Amyotrophic Lateral Sclerosis

(2011) Hussein Daoud et al.   ARCHIVES OF NEUROLOGY

Genomic inflation factors under polygenic inheritance

(2011) Jian Yang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Crohn's disease: NOD2, autophagy and ER stress converge

(2011) T. Fritz et al.   GUT

Inhibition of Microglial Phagocytosis Is Sufficient To Prevent Inflammatory Neuronal Death

(2011) J. J. Neher et al.   JOURNAL OF IMMUNOLOGY

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

(2011) Gosia Trynka et al.   NATURE GENETICS

A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci

(2011) Jonathan P. Bradfield et al.   PLoS Genetics

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

ConsensusPathDB: toward a more complete picture of cell biology

(2010) Atanas Kamburov et al.   NUCLEIC ACIDS RESEARCH

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS