Structurally modified glycyrrhetinic acid derivatives as anti-inflammatory agents

The in vitro and in vivo anti-inflammatory effect of osthole, the major natural coumarin from Cnidium monnieri (L.) Cuss, via the blocking of the activation of the NF-κB and MAPK/p38 pathways

(2019) Huaying Fan et al.   PHYTOMEDICINE

Synthesis, in vitro and in vivo biological evaluation of novel lappaconitine derivatives as potential anti-inflammatory agents

(2019) Lei Pang et al.   Acta Pharmaceutica Sinica B

Anti-inflammatory flavonoids from root bark of Broussonetia papyrifera in LPS-stimulated RAW264.7 cells

(2019) Hyung Won Ryu et al.   BIOORGANIC CHEMISTRY

The anti-inflammatory effects of jiangrines from Jiangella alba through inhibition of p38 and NF-κB signaling pathways

(2019) Peipei Guan et al.   BIOORGANIC CHEMISTRY

Synthesis, anti-inflammatory, p38α MAP kinase inhibitory activities and molecular docking studies of quinoxaline derivatives containing triazole moiety

(2018) Sana Tariq et al.   BIOORGANIC CHEMISTRY

1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity

(2018) Fatima Naaz et al.   BIOORGANIC CHEMISTRY

Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways

(2017) Han-bin Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Xanthotoxin suppresses LPS-induced expression of iNOS, COX-2, TNF-α, and IL-6 via AP-1, NF-κB, and JAK-STAT inactivation in RAW 264.7 macrophages

(2017) Seung-Bin Lee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

18ß-glycyrrhetinic acid derivative promotes proliferation, migration and aquaporin-3 expression in human dermal fibroblasts

(2017) Chi-Feng Hung et al.   PLoS One

Strategies for the Discovery and Development of Anti-Diabetic Drugs from the Natural Products of Traditional Medicines

(2016) Ji-Ming Ye et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Enhancement of anti-bacterial and anti-tumor activities of pentacyclic triterpenes by introducing exocyclic α,β-unsaturated ketone moiety in ring A

(2014) Li R. Huang et al.   MEDICINAL CHEMISTRY RESEARCH

IκB kinase regulation of the TPL-2/ERK MAPK pathway

(2012) Thorsten Gantke et al.   IMMUNOLOGICAL REVIEWS

Synthesis and Pro-Apoptotic Activity of Novel Glycyrrhetinic Acid Derivatives

(2011) Evgeniya B. Logashenko et al.   CHEMBIOCHEM

Synthesis and antitumour activity of glycyrrhetinic acid derivatives

(2010) Stefan Schwarz et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Nonresolving Inflammation

(2010) Carl Nathan et al.   CELL

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology