Free Energy Perturbation in the Design of EED Ligands as Inhibitors of Polycomb Repressive Complex 2 (PRC2) Methyltransferase

Published 2021 View Full Article

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Title
Free Energy Perturbation in the Design of EED Ligands as Inhibitors of Polycomb Repressive Complex 2 (PRC2) Methyltransferase
Authors
Keywords
Free Energy Perturbation, Late stage functionalisation, PRC2, EED, EZH2
Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume -, Issue -, Pages 127904
Publisher
Elsevier BV
Online
2021-03-07
DOI
10.1016/j.bmcl.2021.127904

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