Photodynamic/ photothermal therapy enhances neutrophil-mediated ibrutinib tumor delivery for potent tumor immunotherapy: More than one plus one?

Methotrexate-loaded tumour-cell-derived microvesicles can relieve biliary obstruction in patients with extrahepatic cholangiocarcinoma

(2020) Yunfeng Gao et al.   Nature Biomedical Engineering

Targeted delivery of ibrutinib to tumor-associated macrophages by sialic acid-stearic acid conjugate modified nanocomplexes for cancer immunotherapy

(2019) Qiujun Qiu et al.   Acta Biomaterialia

Tumor Reoxygenation and Blood Perfusion Enhanced Photodynamic Therapy using Ultrathin Graphdiyne Oxide Nanosheets

(2019) Yucai Wang et al.   NANO LETTERS

Neutrophil-Mediated Delivery of Dexamethasone Palmitate-Loaded Liposomes Decorated with a Sialic Acid Conjugate for Rheumatoid Arthritis Treatment

(2019) Ling Hu et al.   PHARMACEUTICAL RESEARCH

Positron Emission Tomography-Guided Photodynamic Therapy with Biodegradable Mesoporous Silica Nanoparticles for Personalized Cancer Immunotherapy

(2019) Cheng Xu et al.   ACS Nano

Redox-Activated Porphyrin-Based Liposome Remote-Loaded with Indoleamine 2,3-Dioxygenase (IDO) Inhibitor for Synergistic Photoimmunotherapy through Induction of Immunogenic Cell Death and Blockage of IDO Pathway

(2019) Dechun Liu et al.   NANO LETTERS

Targeted delivery of pixantrone to neutrophils by poly(sialic acid)- p -octadecylamine conjugate modified liposomes with improved antitumor activity

(2018) Xiang Luo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Novel Self-Assembled Ibrutinib-Phospholipid Complex for Potently Peroral Delivery of Poorly Soluble Drugs with pH-Dependent Solubility

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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway

(2018) Jianqin Lu et al.   ACS Nano

Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B-cell function and inhibition of the PD-1/PD-L1 pathway

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Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence

(2017) Jingwei Xue et al.   Nature Nanotechnology

Myeloid-Derived Suppressor Cells Express Bruton's Tyrosine Kinase and Can Be Depleted in Tumor-Bearing Hosts by Ibrutinib Treatment

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Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

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The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma

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Nanoparticle Targeting of Neutrophils for Improved Cancer Immunotherapy

(2016) Dafeng Chu et al.   Advanced Healthcare Materials

Therapeutic antitumor immunity by checkpoint blockade is enhanced by ibrutinib, an inhibitor of both BTK and ITK

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Bruton Tyrosine Kinase-Dependent Immune Cell Cross-talk Drives Pancreas Cancer

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Reactive Oxygen Species in Inflammation and Tissue Injury

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Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes

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Photodynamic therapy of cancer: An update

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Neutrophils, from Marrow to Microbes

(2010) Niels Borregaard   IMMUNITY

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

(2010) Kaori Sakuishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophil kinetics in health and disease

(2010) Charlotte Summers et al.   TRENDS IN IMMUNOLOGY

Reactive Oxygen Species Regulate Neutrophil Recruitment and Survival in Pneumococcal Pneumonia

(2008) Helen M. Marriott et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

PI3K accelerates, but is not required for, neutrophil chemotaxis to fMLP

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