SILAC-based complexome profiling dissects the structural organization of the human respiratory supercomplexes in SCAFIKO cells

Duplexing complexome profiling with SILAC to study human respiratory chain assembly defects

(2021) Petra Páleníková et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Respiratory supercomplexes act as a platform for complex III ‐mediated maturation of human mitochondrial complexes I and IV

(2020) Margherita Protasoni et al.   EMBO JOURNAL

Pulse-chase SILAC–based analyses reveal selective oversynthesis and rapid turnover of mitochondrial protein components of respiratory complexes

(2020) Daniel F. Bogenhagen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissecting the Roles of Mitochondrial Complex I Intermediate Assembly Complex Factors in the Biogenesis of Complex I

(2020) Luke E. Formosa et al.   Cell Reports

Distinct Roles of Mitochondrial HIGD1A and HIGD2A in Respiratory Complex and Supercomplex Biogenesis

(2020) Alba Timón-Gómez et al.   Cell Reports

Kinetic advantage of forming respiratory supercomplexes

(2020) Alexei Stuchebrukhov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Multiple pathways coordinate assembly of human mitochondrial complex IV and stabilization of respiratory supercomplexes

(2020) Teresa Lobo‐Jarne et al.   EMBO JOURNAL

Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish

(2020) Carolina García‐Poyatos et al.   EMBO REPORTS

Functional role of respiratory supercomplexes in mice: SCAF1 relevance and segmentation of the Qpool

(2020) Enrique Calvo et al.   Science Advances

Respiratory supercomplexes enhance electron transport by decreasing cytochrome c diffusion distance

(2020) Jens Berndtsson et al.   EMBO REPORTS

ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis

(2019) Eduardo Balsa et al.   MOLECULAR CELL

Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk

(2019) James A. Letts et al.   MOLECULAR CELL

The mitochondrial acyl-carrier protein interaction network highlights important roles for LYRM family members in complex I and mitoribosome assembly

(2019) Marris G Dibley et al.   MOLECULAR & CELLULAR PROTEOMICS

Mitochondrial Supercomplexes Do Not Enhance Catalysis by Quinone Channeling

(2018) Justin G. Fedor et al.   Cell Metabolism

Structure of the intact 14-subunit human cytochrome c oxidase

(2018) Shuai Zong et al.   CELL RESEARCH

Respiratory chain supercomplexes: Structures, function and biogenesis

(2018) Teresa Lobo-Jarne et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Building a complex complex: Assembly of mitochondrial respiratory chain complex I

(2018) Luke E. Formosa et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Open questions: respiratory chain supercomplexes—why are they there and what do they do?

(2018) Judy Hirst   BMC BIOLOGY

Tissue- and Condition-Specific Isoforms of Mammalian Cytochrome c Oxidase Subunits: From Function to Human Disease

(2017) Christopher A. Sinkler et al.   Oxidative Medicine and Cellular Longevity

MR-1S Interacts with PET100 and PET117 in Module-Based Assembly of Human Cytochrome c Oxidase

(2017) Sara Vidoni et al.   Cell Reports

The architecture of respiratory supercomplexes

(2016) James A. Letts et al.   NATURE

The architecture of the mammalian respirasome

(2016) Jinke Gu et al.   NATURE

Mechanism of super-assembly of respiratory complexes III and IV

(2016) Sara Cogliati et al.   NATURE

CHOPCHOP v2: a web tool for the next generation of CRISPR genome engineering

(2016) Kornel Labun et al.   NUCLEIC ACIDS RESEARCH

Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes

(2016) Irene Lopez-Fabuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems proteomics of liver mitochondria function

(2016) E. G. Williams et al.   SCIENCE

COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation

(2016) Rafael Pérez-Pérez et al.   Cell Reports

Functional asymmetry and electron flow in the bovine respirasome

(2016) Joana S Sousa et al.   eLife

The Respiratory Chain Supercomplex Organization Is Independent of COX7a2l Isoforms

(2014) Arnaud Mourier et al.   Cell Metabolism

Kinetic evidence against partitioning of the ubiquinone pool and the catalytic relevance of respiratory-chain supercomplexes

(2014) J. N. Blaza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Respiratory Supercomplex Association Limits Production of Reactive Oxygen Species from Complex I

(2013) Evelina Maranzana et al.   ANTIOXIDANTS & REDOX SIGNALING

Methods to analyse composition and dynamics of macromolecular complexes

(2013) Heinrich Heide et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain

(2013) E. Lapuente-Brun et al.   SCIENCE

A stabilizing factor for mitochondrial respiratory supercomplex assembly regulates energy metabolism in muscle

(2013) Kazuhiro Ikeda et al.   Nature Communications

Mitochondrial Complex I Plays an Essential Role in Human Respirasome Assembly

(2012) David Moreno-Lastres et al.   Cell Metabolism

Complexome Profiling Identifies TMEM126B as a Component of the Mitochondrial Complex I Assembly Complex

(2012) Heinrich Heide et al.   Cell Metabolism

Early complex I assembly defects result in rapid turnover of the ND1 subunit

(2012) O. Zurita Rendon et al.   HUMAN MOLECULAR GENETICS

Questioning the functional relevance of mitochondrial supercomplexes by time-resolved analysis of the respiratory chain

(2011) M. Trouillard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mobility and function of Coenzyme Q (ubiquinone) in the mitochondrial respiratory chain

(2009) Giorgio Lenaz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS