Sulfasalazine alleviates neuropathic pain hypersensitivity in mice through inhibition of SGK-1 in the spinal cord

Chronic pain: a review of its epidemiology and associated factors in population-based studies

(2019) Sarah E.E. Mills et al.   BRITISH JOURNAL OF ANAESTHESIA

Concomitant febuxostat enhances methotrexate-induced hepatotoxicity by inhibiting breast cancer resistance protein

(2019) Kenji Ikemura et al.   Scientific Reports

Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential

(2018) Kazuhide Inoue et al.   NATURE REVIEWS NEUROSCIENCE

Analgesic effects of TLR4/NF-κB signaling pathway inhibition on chronic neuropathic pain in rats following chronic constriction injury of the sciatic nerve

(2018) Longhe Xu et al.   BIOMEDICINE & PHARMACOTHERAPY

Sulfasalazine attenuates chronic constriction injury-induced neuroinflammation and mechanical hypersensitivity in rats

(2018) Longfei Ma et al.   NEUROSCIENCE LETTERS

The Circadian Rhythm of Breakthrough Pain Episodes in Terminally-ill Cancer Patients

(2018) Sara Campagna et al.   Cancers

Febuxostat ameliorates secondary progressive experimental autoimmune encephalomyelitis by restoring mitochondrial energy production in a GOT2-dependent manner

(2017) Josephe A. Honorat et al.   PLoS One

Review on TAS-102 development and its use for metastatic colorectal cancer

(2016) Jose Mauricio Mota et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia

(2016) Satoru Koyanagi et al.   Nature Communications

Identification of Febuxostat as a New Strong ABCG2 Inhibitor: Potential Applications and Risks in Clinical Situations

(2016) Hiroshi Miyata et al.   Frontiers in Pharmacology

FLORENCE: a randomized, double-blind, phase III pivotal study of febuxostat versus allopurinol for the prevention of tumor lysis syndrome (TLS) in patients with hematologic malignancies at intermediate to high TLS risk

(2015) M. Spina et al.   ANNALS OF ONCOLOGY

Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway

(2015) Alban Latremoliere et al.   NEURON

Spinal cord stimulation exerts analgesia effects in chronic constriction injury rats via suppression of the TLR4/NF-κB pathway

(2014) Baohong Yuan et al.   NEUROSCIENCE LETTERS

Discovery of N-[4-(1H-Pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides as Highly Active and Selective SGK1 Inhibitors

(2014) Nis Halland et al.   ACS Medicinal Chemistry Letters

Xanthine Oxidase Mediates Axonal and Myelin Loss in a Murine Model of Multiple Sclerosis

(2013) Josephe Archie Honorat et al.   PLoS One

EMD638683, a Novel SGK Inhibitor with Antihypertensive Potency

(2011) Teresa F. Ackermann et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Analgesia by inhibiting tetrahydrobiopterin synthesis

(2011) Michael Costigan et al.   CURRENT OPINION IN PHARMACOLOGY

P-glycoprotein and breast cancer resistance protein expression and function at the blood–brain barrier and blood–cerebrospinal fluid barrier (choroid plexus) in streptozotocin-induced diabetes in rats

(2010) Valeska Reichel et al.   BRAIN RESEARCH

Nociceptor sensitization in pain pathogenesis

(2010) Michael S Gold et al.   NATURE MEDICINE

Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases

(2010) Ali Ryan et al.   Protein & Cell

Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic

(2008) A. B. Sherk et al.   CANCER RESEARCH

Sulfasalazine Blocks the Development of Tactile Allodynia in Diabetic Rats

(2008) L. N. Berti-Mattera et al.   DIABETES