Expanded high-throughput screening and chemotype-enrichment analysis of the phase II: e1k ToxCast library for human sodium-iodide symporter (NIS) inhibition

Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay

(2020) Angela R. Buckalew et al.   ARCHIVES OF TOXICOLOGY

High-throughput screening and chemotype-enrichment analysis of ToxCast phase II chemicals evaluated for human sodium-iodide symporter (NIS) inhibition

(2019) Jun Wang et al.   ENVIRONMENT INTERNATIONAL

Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches

(2019) Pamela D. Noyes et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

ToxRefDB version 2.0: Improved utility for predictive and retrospective toxicology analyses

(2019) Sean Watford et al.   REPRODUCTIVE TOXICOLOGY

High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide Symporter Inhibitors in ToxCast Phase I Chemical Library

(2018) Jun Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Disruption in Thyroid Signaling Pathway: A Mechanism for the Effect of Endocrine-Disrupting Chemicals on Child Neurodevelopment

(2018) Akhgar Ghassabian et al.   Frontiers in Endocrinology

Evaluating iodide recycling inhibition as a novel molecular initiating event for thyroid axis disruption in amphibians

(2018) Jennifer H Olker et al.   TOXICOLOGICAL SCIENCES

Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases

(2018) Jennifer H Olker et al.   TOXICOLOGICAL SCIENCES

Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity

(2017) Michael W Hornung et al.   TOXICOLOGICAL SCIENCES

Development of a screening approach to detect thyroid disrupting chemicals that inhibit the human sodium iodide symporter (NIS)

(2017) Daniel R. Hallinger et al.   TOXICOLOGY IN VITRO

ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology

(2016) Ann M. Richard et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity onIn VitroAssay Activity Across a Diverse Chemical and Assay Space

(2016) Richard Judson et al.   TOXICOLOGICAL SCIENCES

Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries

(2016) Katie Paul Friedman et al.   TOXICOLOGICAL SCIENCES

New Publicly Available Chemical Query Language, CSRML, To Support Chemotype Representations for Application to Data Mining and Modeling

(2015) Chihae Yang et al.   Journal of Chemical Information and Modeling

The sodium/iodide symporter: State of the art of its molecular characterization

(2013) Elisabeth Darrouzet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Tetrac Can Replace Thyroid Hormone During Brain Development in Mouse Mutants Deficient in the Thyroid Hormone Transporter Mct8

(2013) Sigrun Horn et al.   ENDOCRINOLOGY

Thyroid disrupting chemicals: mechanisms and mixtures

(2008) Kevin M. Crofton   INTERNATIONAL JOURNAL OF ANDROLOGY

Transforming Environmental Health Protection

(2008) Francis S. Collins et al.   SCIENCE