Article
Chemistry, Physical
Rosabiela Irfa Andina, Sarawut Kingchok, Kritapas Laohhasurayotin, Nisanart Traiphol, Rakchart Traiphol
Summary: Polydiacetylenes (PDAs) are colorimetric sensor materials that can detect a wide range of stimuli. By modifying their structure and incorporating magnetic nanoparticles, the properties of PDAs can be fine-tuned, offering potential applications in various fields.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Applied
Seungjoo Baek, Mohammed Iqbal Khazi, Jong-Man Kim
Summary: Chemical sensors based on stimulus-responsive chromogenic materials are important for their ability to manipulate optical properties and display vivid colors. In this study, a chromogenic poly-diacetylene (PDA) was generated through polymerization of protonated supramolecular assemblies of a diacetylene precursor. The PDA exhibited a blue color and showed a sensory response to ammonia, transitioning from blue to red and emitting fluorescence upon deprotonation. The self-assembly behavior, topochemical polymerization, and ammonia sensing properties were investigated using spectroscopic methods.
Article
Chemistry, Analytical
Fadilatul Jannah, Jung-Moo Heo, Jaeyoung Park, Jong-Man Kim
Summary: A diaminotriazine (DAT)-containing polydiacetylene (PDA-DAT) colorimetric sensor was developed for selective detection of thymine and oligothymidine. PDA-DAT undergoes a color change in the presence of thymine and oligothymidine due to hydrogen bonding interactions, resulting in absorption spectral shift and corresponding color change. The detection limits for thymine and oligothymidine are 12.6 nM and 14.6 nM, respectively. This study provides a foundation for the design of colorimetric sensors for thymine and oligothymidine.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Polymer Science
Chaoqun Ma, Li Hu, Li Jiang, Wenyan Huang, Hongjun Yang, Qimin Jiang, Bibiao Jiang
Summary: Polydiacetylene (PDA) has been developed as a colorimetric sensor with a unique color response to environmental stimuli. The stability and colorimetric response of blue phase PDA are influenced by noncovalent bonding and strong pi-pi interaction. This study demonstrates the potential of PDA as a colorimetric sensor for detecting subtle environmental changes and measuring the quality of polar organic solvents recovered from industrial effluent.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Shu-Wei Chen, Xipeng Chen, Yang Li, Yalin Yang, Yuchuan Dong, Jinwen Guo, Jinyi Wang
Summary: The development of novel sensors for the detection of lead ions has attracted increasing interest due to their toxic effects on human health and the environment. In this study, two new polydiacetylene-based liposome sensors were developed for the colorimetric and fluorometric recognition of lead ions in aqueous solution. These sensors exhibited high selectivity and sensitivity, and were successfully applied to detect trace amounts of lead ions in real water samples.
Article
Chemistry, Applied
Soojin Jang, Seong Uk Son, Junseok Kim, Hyungjun Kim, Jaewoo Lim, Seung Beom Seo, Byunghoon Kang, Taejoon Kang, Juyeon Jung, Sungbaek Seo, Eun-Kyung Lim
Summary: A colorimetric sensor using PDA-based hydrogel beads has been developed to conveniently detect food spoilage. The sensor can visually confirm the presence of biogenic amines through color changes, providing an efficient and accurate method.
Article
Spectroscopy
Muhammad Arslan, Muhammad Zareef, Haroon Elrasheid Tahir, Xiaodong Zhai, Allah Rakha, Shujat Ali, Jiyong Shi, Xiaobo Zou
Summary: This study evaluated the feasibility of data fusion using colorimetric sensor array (CSA), near-infrared (NIR), and mid-infrared (MIR) spectroscopy for quantifying free fatty acids in rice. Different data sets of low-level and mid-level fusion were used to enhance statistical parameters. The results showed that CSA-NIRML model performed the best in predicting free fatty acid content. Integrating CSA, NIR, and MIR proved to be feasible and improved the prediction accuracy of free fatty acids in rice.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Gizem Beliktay, Tayyaba Shaikh, Emirhan Koca, Hande E. Cingil
Summary: In this study, a reversible colorimetric response of polydiacetylenes to pH change was achieved through structural modifications on the monomer and extended photopolymerization time. Enhanced hydrogen bond forming headgroups and longer UV exposure reduced the response efficiency but enabled reversibility. This research provides a possibility for customized sensing applications.
Article
Materials Science, Multidisciplinary
Rajendran Manikandan, Nitzan Shauloff, Raz Jelinek
Summary: Polymerized chalcone-diacetylene films exhibited remarkable chromatic properties, with reversible thermochromism and selective color and fluorescence transformations induced by ammonia vapor. These films were utilized for high-sensitivity visible detection of bacterial growth and food spoilage in varied temperatures and humidity conditions, offering practical advantages compared to existing food monitoring technologies.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Chemistry, Multidisciplinary
Jiali Chen, Jianlu Zheng, Yuge Hou, Kaori Sugihara
Summary: By utilizing hyperspectral microscopy at visible wavelengths, we are able to present a spatial map of the structural distribution of polydiacetylene (PDA) at the nanoscale within a single crystal. It has been found that the structural variance of PDA, even under the same fabrication conditions, contributes to its poor reproducibility in chemo/biosensing. The tracking of the blue-to-red transition using this technique reveals distinct patterns left by heat or pH stimulation in the transition pathways.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Aphiwat Pankaew, Jirapa Rueangsuwan, Rakchart Traiphol, Nisanart Traiphol
Summary: This study presents a simple method for fabricating colorimetric sensors that can differentiate the concentration and molecular weight of PMMA. The sensitivity of the sensors can be adjusted by experimental parameters.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Hande E. Cingil, Gizem Beliktay, Eric M. M. Tan
Summary: Polydiacetylene(PDA) supramolecules exhibit a conformation-dependent colorimetric response to external triggers, transitioning from the blue phase to the red phase. The study shows that PDA vesicles prepared at an intermediate purple phase exhibit a more sensitive colorimetric response to external triggers compared to those prepared at the blue phase. The supramolecular interactions, including inter- and intra-chain interactions, play a crucial role in causing chain distortions and structural rearrangements of the PDA backbone, in addition to repulsive-ionic head group interactions.
MATERIALS CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Analytical
Justyna Kalisz, Justyna Zarebska, Ewa Kijenska-Gawronska, Krzysztof Maksymiuk, Agata Michalska
Summary: The study tested the suitability of model polydiacetylenes (PDAs) in hydrogen ions sensitive optodes. Nanofibers mats were electrospun using a mixture of polyvinyl chloride (PVC) and polycaprolactone (PCL) together with 10, 12-tricosadiynoic acid (TCDA) or 10,12-pentacosadiynoic acid (PCDA). The PDAs were formed by photopolymerization, resulting in a color change from white to dark blue. The fiber mats exhibited a sigmoidal response to changes in pH, with the color changing from blue to red and the emission intensity decreasing with increasing pH. The proposed nanofibrous mats showed promise for pH sensing in the physiological pH range.
Article
Chemistry, Physical
Jin Zhou, Menglong Duan, Diwen Huang, Hui Shao, Yue Zhou, Yubo Fan
Summary: Researchers have developed a label-free polydiacetylene (PDA) liposome-based colorimetric biosensor for detecting and identifying bacterial cultures at the genus and species level with the naked eye through simple color changes. The sensitivity of the sensor to different bacteria is greatly influenced by the concentration of PDA, phospholipids, and cholesterol in the liposome assemblies, resulting in unique chromatic properties for each bacterial strain. The increase of cholesterol in liposome assemblies enhances the sensitivity of bacterial strains related to membrane destruction, while the detection of certain strains relies on specific recognition elements coupled with the PDA moiety.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Pan Wang, Xidi Liu, Yong You, Mengxue Wang, Yumin Huang, Ying Li, Kui Li, Yuxin Yang, Wei Feng, Qiancheng Liu, Jiaqi Chen, Xulin Yang
Summary: Polyarylene ether nitrile (PEN) nanofibers functionalized with stimuli-response polydiacetylene monomer (PCDA) were successfully fabricated, exhibiting excellent thermal stability and corrosion resistance. The compatibility between PCDA and PEN-PPL was better than that between PCDA and PEN-BPA, resulting in uniform color change with temperature rise. The composite membranes showed good dimensional stability under high temperature and corrosive conditions.
Review
Materials Science, Multidisciplinary
Max Weston, Shu Geng, Rona Chandrawati
Summary: Food sensors have been developed for quality monitoring and contaminant detection to improve food management. However, challenges such as the complexity of food samples, sensor design, and signal processing need to be addressed for successful translation into commercial products.
ADVANCED MATERIALS TECHNOLOGIES
(2021)
Article
Chemistry, Physical
Angie Davina Tjandra, Max Weston, Junwei Tang, Rhiannon P. Kuchel, Rona Chandrawati
Summary: Polydiacetylenes (PDAs) are commonly used for sensing chemical and biological targets. The solvent injection (SI) method offers a viable alternative for large-scale PDA particle production, showing that ethanol and isopropanol are suitable solvents, while water-immiscible solvents like chloroform inhibit particle formation. Higher injection rates result in PDA with greater color intensity, supported by XRD results. The relationship between synthesis flow rate and needle size acts as a stability cut-off point for PDA aggregation.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Chemistry, Multidisciplinary
Yingzhu Zhou, Federico Mazur, Kang Liang, Rona Chandrawati
Summary: This study evaluates the performance of four commercially available fluorescent H2S probes and discusses their suitability in different environments. The results demonstrate the potential of these probes for imaging endogenous H2S in live cells, but also highlight issues in their use and selection.
CHEMISTRY-AN ASIAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Zijie Luo, Yingzhu Zhou, Tao Yang, Yuan Gao, Priyank Kumar, Rona Chandrawati
Summary: Ceria nanoparticles can induce the generation of nitric oxide in addition to scavenging it. This study demonstrates that ceria nanoparticles catalytically decompose S-nitrosoglutathione to produce nitric oxide, with a high release recovery rate and maintained crystalline structure. The newly discovered capability of ceria nanoparticles to generate nitric oxide from GSNO overturns the conventional concept of their role solely as NO-scavenging agents, and shows potential therapeutic effects in cancer cell suppression.
Article
Chemistry, Multidisciplinary
Chengchen Zhang, Biyao Yang, Joanna M. Biazik, Richard F. Webster, Wanjie Xie, Jianbo Tang, Francois-Marie Allioux, Roozbeh Abbasi, Maedehsadat Mousavi, Ewa M. Goldys, Kristopher A. Kilian, Rona Chandrawati, Dorna Esrafilzadeh, Kourosh Kalantar-Zadeh
Summary: This study reveals the mechanisms of gallium as an anti-inflammatory by delivering gallium nanodroplets into macrophages. The gallium nanodroplets selectively inhibit nitric oxide production without affecting the accumulation of pro-inflammatory mediators. This study provides new insights for the use of gallium in anti-inflammatory and future biomedical applications.
Article
Chemistry, Physical
Angie Davina Tjandra, Andy-Hoai Pham, Rona Chandrawati
Summary: Volatile organic compound (VOC) detection has expanded to food quality control and disease diagnosis. Polydiacetylenes (PDAs) as colorimetric sensors have unique properties and are extensively studied. This Perspective provides an overview of PDA-based VOC detection systems and identifies areas for improvement in future research and considerations for device fabrication.
CHEMISTRY OF MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Arbel Artzy-Schnirman, Enas Abu-Shah, Rona Chandrawati, Efrat Altman, Norkhairin Yusuf, Shih-Ting Wang, Jose Ramos, Catherine S. Hansel, Maya Haus-Cohen, Rony Dahan, Sefina Arif, Michael L. Dustin, Mark Peakman, Yoram Reiter, Molly M. Stevens
Summary: The study develops a unique artificial antigen-presenting cell system that can detect and target autoreactive T-cell populations, providing a promising tool for preventing autoimmune diseases.
Article
Chemistry, Multidisciplinary
Zijie Luo, Gervase Ng, Yingzhu Zhou, Cyrille Boyer, Rona Chandrawati
Summary: Polymeric amines have been discovered to induce NO generation from RSNOs, and controlled NO release can be achieved by adjusting various factors. The NO-releasing feature can be integrated into different materials, and the potential of PVA/PEI hydrogels in Pseudomonas aeruginosa biofilm prevention has been demonstrated. The discovery in this study opens up new opportunities in NO-generating biomaterials for antibacterial, antiviral, anticancer, antithrombotic, and wound healing applications.
Article
Materials Science, Multidisciplinary
Federico Mazur, Fabio Lisi, Zhipeng Ma, Rona Chandrawati
Summary: The ongoing COVID-19 pandemic has posed a significant challenge to healthcare systems globally. In response to the World Health Organization's recommendations, face masks have been widely used to reduce the spread of the virus. This increased demand for face masks has led to the development of a novel technology that incorporates therapeutic benefits, such as delivering inhaled nitric oxide (iNO) therapy. By utilizing humidity-triggered NO-releasing nanoparticles, a face mask has been developed that can provide sustained low-dose release of 2.1-2.5 ppm NO for 90 minutes. This innovative mask has the potential to alleviate the strain on financially limited healthcare systems in developing regions.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Review
Materials Science, Multidisciplinary
Ke Shi, Chuwen Song, Yayi Wang, Rona Chandrawati, Yiyang Lin
Summary: This review presents recent advances in the design of bioinspired systems that mimic transmembrane signaling in synthetic and living cells. The building of cell-like membranous structures and the construction of interfacial recognition between chemical or biological components are summarized. The possibilities of mimicking transmembrane signaling with transducer integrated systems are highlighted, along with the potential for applying supramolecular materials to interact with surface receptors on the plasma membrane.
COMMUNICATIONS MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Federico Mazur, Andy-Hoai Pham, Rona Chandrawati
Summary: Catalysts play a crucial role in various aspects of life by increasing the rate of chemical and biological reactions. Polymer catalysts, either as supports or as catalysts themselves, have been widely used in medical, environmental, and energy applications.
APPLIED MATERIALS TODAY
(2023)
Review
Chemistry, Multidisciplinary
Fareeha Arshad, Noor Faizah Mohd-Naim, Rona Chandrawati, Daniel Cozzolino, Minhaz Uddin Ahmed
Summary: This article discusses the recent developments of nanozyme-based sensors for detecting biomarkers associated with food quality and safety. It provides a brief introduction to the topic and discusses the different types of sensors used in food biomarker detection. The article highlights recent studies on nanozyme-based sensors for detecting various food markers and also discusses the challenges and possible solutions towards the development of nanozyme-based sensors in the food industry. The review concludes by discussing the future perspectives of this field for successful detection and monitoring of food analytes.
Review
Materials Science, Multidisciplinary
Max Weston, Andy-Hoai Pham, Jennessa Tubman, Yuan Gao, Angie Davina Tjandra, Rona Chandrawati
Summary: Polydiacetylene (PDA) sensors are developed as food management tools due to their convenient colorimetric signal, low cost, versatility, and ability to be incorporated into food packaging materials and devices. This review discusses PDA sensor fabrication methods, their application as food quality and contaminant sensors, and their integration into materials and devices. Different PDA sensor formats for food applications, including solution-based tests and substrate-based sensors like hydrogels and films, are evaluated. The challenges and opportunities for future research in PDA food sensors are also discussed.
MATERIALS ADVANCES
(2022)
Review
Nanoscience & Nanotechnology
Yingzhu Zhou, Federico Mazur, Qingqing Fan, Rona Chandrawati
Summary: H2S is involved in various biological processes and diseases, leading to the development of analytical methods for its detection, with fluorescence-based assays offering good sensitivity and specificity. Nanotechnology has been utilized to develop highly sensitive and specific fluorescent nanoprobes for real-time detection and imaging.
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)