Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds

DNA methylation QTL analysis identifies new regulators of human longevity

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A Quarter Century of APOE and Alzheimer’s Disease: Progress to Date and the Path Forward

(2019) Michaël E. Belloy et al.   NEURON

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Enhancer variants associated with Alzheimer’s disease affect gene expression via chromatin looping

(2019) Masataka Kikuchi et al.   BMC Medical Genomics

DNA methylation in the APOE genomic region is associated with cognitive function in African Americans

(2018) Jiaxuan Liu et al.   BMC Medical Genomics

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(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Bias, robustness and scalability in single-cell differential expression analysis

(2018) Charlotte Soneson et al.   NATURE METHODS

Expression of nucleotide excision repair in Alzheimer’s disease is higher in brain tissue than in blood

(2018) Helge Leander B. Jensen et al.   NEUROSCIENCE LETTERS

Normal aging induces A1-like astrocyte reactivity

(2018) Laura E. Clarke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations

(2018) Farid Rajabli et al.   PLoS Genetics

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

(2017) Yang Shi et al.   NATURE

Neurotoxic reactive astrocytes are induced by activated microglia

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Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis

(2017) Tien-Phat V. Huynh et al.   NEURON

Transcriptome Analysis Reveals Neuroprotective aspects of Human Reactive Astrocytes induced by Interleukin 1β

(2017) Daniel Boon Loong Teh et al.   Scientific Reports

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

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A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

APOE ε4 and the risk for Alzheimer disease and cognitive decline in African Americans and Yoruba

(2014) Hugh C. Hendrie et al.   INTERNATIONAL PSYCHOGERIATRICS

RFMix: A Discriminative Modeling Approach for Rapid and Robust Local-Ancestry Inference

(2013) Brian K. Maples et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ϵ4, and the Risk of Late-Onset Alzheimer Disease in African Americans

(2013) Christiane Reitz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Biomarker Modeling of Alzheimer’s Disease

(2013) Clifford R. Jack et al.   NEURON

Genomic Analysis of Reactive Astrogliosis

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A framework for variation discovery and genotyping using next-generation DNA sequencing data

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