Metal-Organic Frameworks for Therapeutic Gas Delivery

Tuning Cellular Biological Functions Through the Controlled Release of NO from a Porous Ti-MOF

(2020) Rosana V. Pinto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbon monoxide and its donors - Chemical and biological properties

(2020) Weronika Adach et al.   CHEMICO-BIOLOGICAL INTERACTIONS

MOF Materials for the Capture of Highly Toxic H2S and SO2

(2020) Eva Martínez-Ahumada et al.   ORGANOMETALLICS

Biogenic nanobubbles for effective oxygen delivery and enhanced photodynamic therapy of cancer

(2020) Lin Song et al.   Acta Biomaterialia

Metal–Organic Framework Derived Nanozymes in Biomedicine

(2020) Dongdong Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Copper-Based SURMOFs for Nitric Oxide Generation: Hemocompatibility, Vascular Cell Growth, and Tissue Response

(2019) Qian Zhao et al.   ACS Applied Materials & Interfaces

ZIF-8 degrades in cell media, serum, and some—but not all—common laboratory buffers

(2019) Michael A. Luzuriaga et al.   SUPRAMOLECULAR CHEMISTRY

Thermal-Responsive Carbon Monoxide (CO) Delivery Expedites Metabolic Exhaustion of Cancer Cells toward Reversal of Chemotherapy Resistance

(2019) Yongjuan Li et al.   ACS Central Science

Fluorescent nanoprobes for the sensing of gasotransmitters hydrogen sulfide (H2S), nitric oxide (NO) and carbon monoxide (CO)

(2019) D. Amilan Jose et al.   METHODS

O2-Cu/ZIF-8@Ce6/ZIF-8@F127 Composite as a Tumor Microenvironment-Responsive Nanoplatform with Enhanced Photo-/Chemodynamic Antitumor Efficacy

(2019) Zhongxi Xie et al.   ACS Applied Materials & Interfaces

Activatable Small Molecule H2S Donors

(2019) Carolyn M Levinn et al.   ANTIOXIDANTS & REDOX SIGNALING

Electrochemical Nitric Oxide Sensors: Principles of Design and Characterization

(2019) Micah D. Brown et al.   CHEMICAL REVIEWS

Toxicity screening of two prevalent metal organic frameworks for therapeutic use in human lung epithelial cells

(2019) Alixandra Wagner et al.   International Journal of Nanomedicine

Cell Membrane-Coated Porphyrin Metal–Organic Frameworks for Cancer Cell Targeting and O2-Evolving Photodynamic Therapy

(2019) Di Zhang et al.   ACS Applied Materials & Interfaces

Clinical use of inhaled nitric oxide: Local and systemic applications

(2019) Megan Barnes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxygen-Self-Supplying and HIF-1α-Inhibiting Core–Shell Nanosystem for Hypoxia-Resistant Photodynamic Therapy

(2019) Peng Liu et al.   ACS Applied Materials & Interfaces

A pH/Ultrasound dual-response biomimetic nanoplatform for nitric oxide gas-sonodynamic combined therapy and repeated ultrasound for relieving hypoxia

(2019) Jie An et al.   BIOMATERIALS

Enzyme Prodrug Therapy Achieves Site-Specific, Personalized Physiological Responses to the Locally Produced Nitric Oxide

(2018) Anna K. Winther et al.   ACS Applied Materials & Interfaces

Oxygen-Generating MnO2 Nanodots-Anchored Versatile Nanoplatform for Combined Chemo-Photodynamic Therapy in Hypoxic Cancer

(2018) Wentao Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

A review of hydrogen sulfide (H 2 S) donors: Chemistry and potential therapeutic applications

(2018) Chadwick R. Powell et al.   BIOCHEMICAL PHARMACOLOGY

Biomimetic O 2 -Evolving metal-organic framework nanoplatform for highly efficient photodynamic therapy against hypoxic tumor

(2018) Shutao Gao et al.   BIOMATERIALS

Intelligent Metal Carbonyl Metal-Organic Framework Nanocomplex for Fluorescent Traceable H2 O2 -Triggered CO Delivery

(2018) Zhaokui Jin et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Phase II Clinical Trial of Low-Dose Inhaled Carbon Monoxide in Idiopathic Pulmonary Fibrosis

(2018) Ivan O. Rosas et al.   CHEST

Platinum nanoparticles: an avenue for enhancing the release of nitric oxide from S-nitroso-N-acetylpenicillamine and S-nitrosoglutathione

(2018) Gao-Juan Cao et al.   Nanoscale

A Multifunctional Biomimetic Nanoplatform for Relieving Hypoxia to Enhance Chemotherapy and Inhibit the PD-1/PD-L1 Axis

(2018) Mei-Zhen Zou et al.   Small

Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells

(2018) Shuang Peng et al.   Nature Communications

Progress and Promise of Nitric Oxide-Releasing Platforms

(2018) Tao Yang et al.   Advanced Science

Theranostic Mn-Porphyrin Metal–Organic Frameworks for Magnetic Resonance Imaging-Guided Nitric Oxide and Photothermal Synergistic Therapy

(2018) Hui Zhang et al.   ACS Applied Materials & Interfaces

Coordination Modulation Method To Prepare New Metal–Organic Framework-Based CO-Releasing Materials

(2018) Francisco J. Carmona et al.   ACS Applied Materials & Interfaces

Gas-Generating Nanoplatforms: Material Chemistry, Multifunctionality, and Gas Therapy

(2018) Luodan Yu et al.   ADVANCED MATERIALS

Overcoming tumor hypoxia as a barrier to radiotherapy, chemotherapy and immunotherapy in cancer treatment

(2018) Kaitlin Graham et al.   International Journal of Nanomedicine

Synthesis of Aryl Silacarboxylates via Palladium-Catalyzed C–O Bond Formation of Silacarboxylic Acids and Aryl Iodides

(2018) Jin-Yan Liang et al.   ORGANIC LETTERS

A zirconium-based metal-organic framework with encapsulated anionic drug for uncommonly controlled oral drug delivery

(2018) Ke Jiang et al.   MICROPOROUS AND MESOPOROUS MATERIALS

On-demand CO release for amplification of chemotherapy by MOF functionalized magnetic carbon nanoparticles with NIR irradiation

(2018) Jizong Yao et al.   BIOMATERIALS

Impaired Hydrogen Sulfide–Mediated Vasodilation Contributes to Microvascular Endothelial Dysfunction in Hypertensive AdultsNovelty and Significance

(2017) Jody L. Greaney et al.   HYPERTENSION

Attenuation of Antioxidant Capacity in Human Breast Cancer Cells by Carbon Monoxide through Inhibition of Cystathionine β-Synthase Activity: Implications in Chemotherapeutic Drug Sensitivity

(2017) Brian Kawahara et al.   JOURNAL OF MEDICINAL CHEMISTRY

Toward Hydrogen Sulfide Based Therapeutics: Critical Drug Delivery and Developability Issues

(2017) Yueqin Zheng et al.   MEDICINAL RESEARCH REVIEWS

Detection of Reactive Oxygen and Nitrogen Species by Electron Paramagnetic Resonance (EPR) Technique

(2017) Sibel Suzen et al.   MOLECULES

Light responsive metal–organic frameworks as controllable CO-releasing cell culture substrates

(2017) Stéphane Diring et al.   Chemical Science

Water-Stable Metal–Organic Framework/Polymer Composites Compatible with Human Hepatocytes

(2016) Megan J. Neufeld et al.   ACS Applied Materials & Interfaces

Controllable CO Release Following Near-Infrared Light-Induced Cleavage of Iron Carbonyl Derivatized Prussian Blue Nanoparticles for CO-Assisted Synergistic Treatment

(2016) Wei-Peng Li et al.   ACS Nano

An O2Self-Sufficient Biomimetic Nanoplatform for Highly Specific and Efficient Photodynamic Therapy

(2016) Hong Cheng et al.   ADVANCED FUNCTIONAL MATERIALS

Electrochemical hydrogen sulfide biosensors

(2016) Tailin Xu et al.   ANALYST

Outstanding drug loading capacity by water stable microporous MOF: a potential drug carrier

(2016) Partha Pratim Bag et al.   CHEMICAL COMMUNICATIONS

Metal organic frameworks mimicking natural enzymes: a structural and functional analogy

(2016) Ipsita Nath et al.   CHEMICAL SOCIETY REVIEWS

PhotoCORMs: CO release moves into the visible

(2016) Mark A. Wright et al.   DALTON TRANSACTIONS

Toxicity of nanoscale metal organic frameworks: a perspective

(2016) Muhammad Sajid   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Gaseous nitric oxide to treat antibiotic resistant bacterial and fungal lung infections in patients with cystic fibrosis: a phase I clinical study

(2016) Caroline Deppisch et al.   INFECTION

Tuning the nitric oxide release from CPO-27 MOFs

(2016) Damiano Cattaneo et al.   RSC Advances

Underlying mechanism of the hydrothermal instability of Cu3(BTC)2 metal-organic framework

(2016) Nadeen Al-Janabi et al.   Frontiers of Chemical Science and Engineering

Immobilization of Metal–Organic Framework Copper(II) Benzene-1,3,5-tricarboxylate (CuBTC) onto Cotton Fabric as a Nitric Oxide Release Catalyst

(2015) Megan J. Neufeld et al.   ACS Applied Materials & Interfaces

Role of nitric oxide in murine conventional outflow physiology

(2015) Jason Y. H. Chang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The real-time in vivo electrochemical measurement of nitric oxide and carbon monoxide release upon direct epidural electrical stimulation of the rat neocortex

(2015) Sarah S. Park et al.   ANALYST

Anti-Inflammatory and Cytoprotective Actions of Hydrogen Sulfide: Translation to Therapeutics

(2015) John L. Wallace et al.   ANTIOXIDANTS & REDOX SIGNALING

A Novel Hydrogen Sulfide Prodrug, SG1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients

(2015) David J. Polhemus et al.   Cardiovascular Therapeutics

A Tunable, Stable, and Bioactive MOF Catalyst for Generating a Localized Therapeutic from Endogenous Sources

(2014) Jacqueline L. Harding et al.   ADVANCED FUNCTIONAL MATERIALS

Carbon-Monoxide-Releasing Molecules for the Delivery of Therapeutic CO In Vivo

(2014) Sandra García-Gallego et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Exenatide induces aortic vasodilation increasing hydrogen sulphide, carbon monoxide and nitric oxide production

(2014) Eszter Sélley et al.   Cardiovascular Diabetology

Exploiting Intrinsic Nanoparticle Toxicity: The Pros and Cons of Nanoparticle-Induced Autophagy in Biomedical Research

(2014) Karen Peynshaert et al.   CHEMICAL REVIEWS

Carbon Monoxide, Hydrogen Sulfide, and Nitric Oxide as Signaling Molecules in the Gastrointestinal Tract

(2014) Gianrico Farrugia et al.   GASTROENTEROLOGY

Gasotransmitters: growing pains and joys

(2014) Rui Wang   TRENDS IN BIOCHEMICAL SCIENCES

Synthesis and Characterization of a “Turn-On” photoCORM for Trackable CO Delivery to Biological Targets

(2014) Samantha J. Carrington et al.   ACS Medicinal Chemistry Letters

Hydrogen sulfide chemical biology: Pathophysiological roles and detection

(2013) Gopi K. Kolluru et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Shape- and Nitric Oxide Flux-Dependent Bactericidal Activity of Nitric Oxide-Releasing Silica Nanorods

(2013) Yuan Lu et al.   Small

Composite materials with embedded metal organic framework catalysts for nitric oxide release from bioavailable S-nitrosothiols

(2013) Jacqueline L. Harding et al.   Journal of Materials Chemistry B

Carbon monoxide: present and future indications for a medical gas

(2013) Stefan W. Ryter et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Nitric Oxide-Releasing Dendrimers as Antibacterial Agents

(2012) Bin Sun et al.   BIOMACROMOLECULES

Nitric oxide release: Part II. Therapeutic applications

(2012) Alexis W. Carpenter et al.   CHEMICAL SOCIETY REVIEWS

Fluorescent probes for sensing and imaging biological hydrogen sulfide

(2012) Vivian S Lin et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The potential of organometallic complexes in medicinal chemistry

(2012) Gilles Gasser et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Metal–organic frameworks for the storage and delivery of biologically active hydrogen sulfide

(2012) Phoebe K. Allan et al.   DALTON TRANSACTIONS

A spectrophotometric method for the detection of carboxymyoglobin in beef drip

(2012) Enrica Droghetti et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

Metal Organic Frameworks as Nitric Oxide Catalysts

(2012) Jacqueline L. Harding et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acyloxybutadiene Iron Tricarbonyl Complexes as Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)

(2011) Steffen Romanski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Differential Antibacterial Activity Against Pseudomonas aeruginosa by Carbon Monoxide-Releasing Molecules

(2011) Mathieu Desmard et al.   ANTIOXIDANTS & REDOX SIGNALING

NONOates–Polyethylenimine Hydrogel for Controlled Nitric Oxide Release and Cell Proliferation Modulation

(2011) Jihoon Kim et al.   BIOCONJUGATE CHEMISTRY

Structurally Diverse Nitric Oxide-Releasing Poly(propylene imine) Dendrimers

(2011) Yuan Lu et al.   CHEMISTRY OF MATERIALS

Silacarboxylic Acids as Efficient Carbon Monoxide Releasing Molecules: Synthesis and Application in Palladium-Catalyzed Carbonylation Reactions

(2011) Stig D. Friis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cellular toxicity of inorganic nanoparticles: Common aspects and guidelines for improved nanotoxicity evaluation

(2011) Stefaan J. Soenen et al.   Nano Today

Regulation of cardiovascular cell function by hydrogen sulfide (H2S)

(2010) David J Elsey et al.   CELL BIOCHEMISTRY AND FUNCTION

Interaction of hydrogen sulfide with ion channels

(2010) Guanghua Tang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?

(2010) Alaaldin M. Alkilany et al.   JOURNAL OF NANOPARTICLE RESEARCH

The therapeutic potential of carbon monoxide

(2010) Roberto Motterlini et al.   NATURE REVIEWS DRUG DISCOVERY

Syntheses, structural characterization and CO releasing properties of boranocarbonate [H3BCO2H]− derivatives

(2010) Tamil Selvi Pitchumony et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Hyperbaric oxygen therapy as an anti-infective agent

(2009) Maide Çimşit et al.   Expert Review of Anti-Infective Therapy

Nitric Oxide Chemisorption in a Postsynthetically Modified Metal−Organic Framework

(2009) Michael J. Ingleson et al.   INORGANIC CHEMISTRY

Therapeutic Antioxidant Medical Gas

(2009) Atsunori Nakao et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Signaling by Gasotransmitters

(2009) A. K. Mustafa et al.   Science Signaling

Gas Storage in Nanoporous Materials

(2008) Russell E. Morris et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Exceptional Behavior over the Whole Adsorption−Storage−Delivery Cycle for NO in Porous Metal Organic Frameworks

(2008) Alistair C. McKinlay et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The use of hyperbaric oxygen therapy to treat chronic wounds: A review

(2008) Jennifer A. Thackham et al.   WOUND REPAIR AND REGENERATION