Thirty years of mirena: A story of innovation and change in women's healthcare

Since its introduction in 1990, the levonorgestrel-releasing intrauterine system (LNG-IUS) has played a key role in shaping the healthcare landscape of women. Here we explore the development of the first LNG-IUS (Mirena (R)) and the early clinical trials that demonstrated its potential. We highlight the contraceptive and therapeutic benefits of Mirena (R), and discuss how clinical practice has been changed since the introduction of LNG-IUS and other long-acting reversible contraceptive methods. The history of Mirena (R) is rich in innovation and has also paved the way to the development of smaller intrauterine systems with lower hormone doses. Along with Mirena (R), these newer LNG-IUS contribute to improving contraceptive choices for women, allowing them to select the option that is right for them and that meets their needs no matter their age, parity or circumstances.

Automated summary

The levonorgestrel-releasing intrauterine system (LNG-IUS) introduced in 1990 has played a crucial role in shaping women's healthcare. The development and early clinical trials of the first LNG-IUS (Mirena (R)) demonstrated its potential in providing contraceptive and therapeutic benefits, leading to changes in clinical practice. The rich history of Mirena (R) has paved the way for smaller intrauterine systems with lower hormone doses, alongside newer LNG-IUS, contributing to improving contraceptive choices for women.