Immunoglobulin G Is a Novel Substrate for the Endocytic Protein Megalin

Megalin-mediated albumin endocytosis in cultured murine mesangial cells

(2020) Mark A. Bryniarski et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tutorial on Monoclonal Antibody Pharmacokinetics and its Considerations in Early Development

(2018) Meric Ovacik et al.   CTS-Clinical and Translational Science

Proteomic Analysis of Charcoal-Stripped Fetal Bovine Serum Reveals Changes in the Insulin-Like Growth Factor Signaling Pathway

(2018) Chengjian Tu et al.   JOURNAL OF PROTEOME RESEARCH

Abolishment of proximal tubule albumin endocytosis does not affect plasma albumin during nephrotic syndrome in mice

(2018) Kathrin Weyer et al.   KIDNEY INTERNATIONAL

IonStar enables high-precision, low-missing-data proteomics quantification in large biological cohorts

(2018) Xiaomeng Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surfactant Cocktail-Aided Extraction/Precipitation/On-Pellet Digestion Strategy Enables Efficient and Reproducible Sample Preparation for Large-Scale Quantitative Proteomics

(2018) Shichen Shen et al.   ANALYTICAL CHEMISTRY

An IonStar Experimental Strategy for MS1 Ion Current-Based Quantification Using Ultrahigh-Field Orbitrap: Reproducible, In-Depth, and Accurate Protein Measurement in Large Cohorts

(2017) Xiaomeng Shen et al.   JOURNAL OF PROTEOME RESEARCH

Increase of Total Nephron Albumin Filtration and Reabsorption in Diabetic Nephropathy

(2016) Keita P. Mori et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Megalin and cubilin in proximal tubule protein reabsorption: from experimental models to human disease

(2016) Rikke Nielsen et al.   KIDNEY INTERNATIONAL

Effect of Type 2 Diabetes Mellitus and Diabetic Nephropathy on IgG Pharmacokinetics and Subcutaneous Bioavailability in the Rat

(2015) Gurkishan S. Chadha et al.   AAPS Journal

Nephrin Preserves Podocyte Viability and Glomerular Structure and Function in Adult Kidneys

(2015) X. Li et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and development

(2015) Jay Tibbitts et al.   mAbs

Strategic Approaches to Optimizing Peptide ADME Properties

(2014) Li Di   AAPS Journal

Megalin–deficiency causes high myopia, retinal pigment epithelium-macromelanosomes and abnormal development of the ciliary body in mice

(2014) Tina Storm et al.   CELL AND TISSUE RESEARCH

ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression

(2013) Mehul Shah et al.   JOURNAL OF CELL BIOLOGY

Large-Scale, Ion-Current-Based Proteomics Investigation of Bronchoalveolar Lavage Fluid in Chronic Obstructive Pulmonary Disease Patients

(2013) Chengjian Tu et al.   JOURNAL OF PROTEOME RESEARCH

Investigation of the Influence of Nephropathy on Monoclonal Antibody Disposition: A Pharmacokinetic Study in a Mouse Model of Diabetic Nephropathy

(2013) Frank A. Engler et al.   PHARMACEUTICAL RESEARCH

Endocytic Receptors in the Renal Proximal Tubule

(2012) Erik I. Christensen et al.   PHYSIOLOGY

Megalin/Cubilin-mediated Uptake of FITC-labeled IgG by OK Kidney Epithelial Cells

(2011) Junya Nagai et al.   Drug Metabolism and Pharmacokinetics

The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

(2011) Kristen L. Meerbrey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Renal uptake of different radiolabelled peptides is mediated by megalin: SPECT and biodistribution studies in megalin-deficient mice

(2010) Erik Vegt et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Nephrotoxicity in Mice After Repeated Imaging Using 111In-Labeled Peptides

(2010) M. Melis et al.   JOURNAL OF NUCLEAR MEDICINE

Cubilin Is Essential for Albumin Reabsorption in the Renal Proximal Tubule

(2010) S. Amsellem et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Receptor-mediated endocytosis in renal proximal tubule

(2009) Erik Ilsø Christensen et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Monoclonal Antibody Pharmacokinetics and Pharmacodynamics

(2008) W Wang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Megalin contributes to the early injury of proximal tubule cells during nonselective proteinuria

(2008) Yaeko Motoyoshi et al.   KIDNEY INTERNATIONAL

Proteinuria in diabetic kidney disease: A mechanistic viewpoint

(2008) J.A. Jefferson et al.   KIDNEY INTERNATIONAL