The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity

Quantifying the heterogeneity of macromolecular machines by mass photometry

(2020) Adar Sonn-Segev et al.   Nature Communications

Benchmarking fold detection by DaliLite v.5

(2019) Liisa Holm   BIOINFORMATICS

Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21

(2019) Dae-Seok Kim et al.   MOLECULAR CELL

Enhancer-mediated enrichment of interacting JMJD3–DDX21 to ENPP2 locus prevents R-loop formation and promotes transcription

(2019) Deborah Argaud et al.   NUCLEIC ACIDS RESEARCH

The mechanism of RNA duplex recognition and unwinding by DEAD-box helicase DDX3X

(2019) He Song et al.   Nature Communications

Dissecting the role of DDX21 in regulating HCMV replication

(2019) Hongyun Hao et al.   JOURNAL OF VIROLOGY

An RNA guanine quadruplex regulated pathway to TRAIL-sensitization by DDX21

(2019) Ewan K.S. McRae et al.   RNA

Insights into the RNA quadruplex binding specificity of DDX21

(2018) Ewan K.S. McRae et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A Survey of DDX21 Activity During Rev/RRE Complex Formation

(2018) John A. Hammond et al.   JOURNAL OF MOLECULAR BIOLOGY

A double-negative feedback loop between DEAD-box protein DDX21 and Snail regulates epithelial-mesenchymal transition and metastasis in breast cancer

(2018) Hao Zhang et al.   CANCER LETTERS

Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders

(2018) Eliezer Calo et al.   NATURE

SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability

(2017) Chenlin Song et al.   GENES & DEVELOPMENT

NOLB: Nonlinear Rigid Block Normal-Mode Analysis Method

(2017) Alexandre Hoffmann et al.   Journal of Chemical Theory and Computation

Biochemical Differences and Similarities between the DEAD-Box Helicase Orthologs DDX3X and Ded1p

(2017) Deepak Sharma et al.   JOURNAL OF MOLECULAR BIOLOGY

Human DDX21 binds and unwinds RNA guanine quadruplexes

(2017) Ewan K.S. McRae et al.   NUCLEIC ACIDS RESEARCH

Structural Insights into a Unique Dimeric DEAD-Box Helicase CshA that Promotes RNA Decay

(2017) Jennifer Huen et al.   STRUCTURE

Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions

(2017) Ling Xu et al.   STRUCTURE

DDX21 translocates from nucleus to cytoplasm and stimulates the innate immune response due to dengue virus infection

(2016) Yangchao Dong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The importance of dynamics in integrative modeling of supramolecular assemblies

(2015) Giorgio E Tamò et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The conformational plasticity of eukaryotic RNA-dependent ATPases

(2015) Sevim Ozgur et al.   FEBS Journal

Division of Labor in an Oligomer of the DEAD-Box RNA Helicase Ded1p

(2015) Andrea A. Putnam et al.   MOLECULAR CELL

R loops: new modulators of genome dynamics and function

(2015) José M. Santos-Pereira et al.   NATURE REVIEWS GENETICS

The tale of RNA G-quadruplex

(2015) Prachi Agarwala et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Advanced ensemble modelling of flexible macromolecules using X-ray solution scattering

(2015) Giancarlo Tria et al.   IUCrJ

RNA Helicase Proteins as Chaperones and Remodelers

(2014) Inga Jarmoskaite et al.   Annual Review of Biochemistry

Cellular DDX21 RNA Helicase Inhibits Influenza A Virus Replication but Is Counteracted by the Viral NS1 Protein

(2014) Guifang Chen et al.   Cell Host & Microbe

RNA helicase DDX21 coordinates transcription and ribosomal RNA processing

(2014) Eliezer Calo et al.   NATURE

DEAD-box RNA helicase domains exhibit a continuum between complete functional independence and high thermodynamic coupling in nucleotide and RNA duplex recognition

(2014) Brighton Samatanga et al.   NUCLEIC ACIDS RESEARCH

The association of late-acting snoRNPs with human pre-ribosomal complexes requires the RNA helicase DDX21

(2014) Katherine E. Sloan et al.   NUCLEIC ACIDS RESEARCH

Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism

(2013) Matteo T Degiacomi et al.   Nature Chemical Biology

Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera

(2013) Lenz Steimer et al.   NUCLEIC ACIDS RESEARCH

ATP Utilization and RNA Conformational Rearrangement by DEAD-Box Proteins

(2012) Arnon Henn et al.   Annual Review of Biophysics

RRM–RNA recognition: NMR or crystallography…and new findings

(2012) Gerrit M Daubner et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

How Random are Intrinsically Disordered Proteins? A Small Angle Scattering Perspective

(2012) Veronique Receveur-Brechot et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p

(2012) Anna L. Mallam et al.   NATURE

Isolation of Human Mitotic Protein Phosphatase Complexes: Identification of a Complex between Protein Phosphatase 1 and the RNA Helicase Ddx21

(2012) Veerle De Wever et al.   PLoS One

DDX1, DDX21, and DHX36 Helicases Form a Complex with the Adaptor Molecule TRIF to Sense dsRNA in Dendritic Cells

(2011) Zhiqiang Zhang et al.   IMMUNITY

Host Cell Interactome of HIV-1 Rev Includes RNA Helicases Involved in Multiple Facets of Virus Production

(2011) Souad Naji et al.   MOLECULAR & CELLULAR PROTEOMICS

From unwinding to clamping — the DEAD box RNA helicase family

(2011) Patrick Linder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Solution structures of DEAD-box RNA chaperones reveal conformational changes and nucleic acid tethering by a basic tail

(2011) A. L. Mallam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unwinding by Local Strand Separation Is Critical for the Function of DEAD-Box Proteins as RNA Chaperones

(2009) Mark Del Campo et al.   JOURNAL OF MOLECULAR BIOLOGY

c-Jun Supports Ribosomal RNA Processing and Nucleolar Localization of RNA Helicase DDX21

(2008) Tim H. Holmström et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The putative RNase P motif in the DEAD box helicase Hera is dispensable for efficient interaction with RNA and helicase activity

(2008) Martin H. Linden et al.   NUCLEIC ACIDS RESEARCH

A novel dimerization motif in the C-terminal domain of the Thermus thermophilus DEAD box helicase Hera confers substantial flexibility †

(2008) Dagmar Klostermeier et al.   NUCLEIC ACIDS RESEARCH

ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding

(2008) F. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution structure of the GUCT domain from human RNA helicase II/Guβ reveals the RRM fold, but implausible RNA interactions

(2008) Satoshi Ohnishi et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Function of the C-terminal Domain of the DEAD-box Protein Mss116p Analyzed in Vivo and in Vitro

(2007) Georg Mohr et al.   JOURNAL OF MOLECULAR BIOLOGY