Dopamine D2 Long Receptors Are Critical for Caveolae-Mediated α-Synuclein Uptake in Cultured Dopaminergic Neurons

Initiation and propagation of α-synuclein aggregation in the nervous system

(2020) Baraa A. Hijaz et al.   Molecular Neurodegeneration

Fatty Acid Binding Protein 3 Enhances the Spreading and Toxicity of α-Synuclein in Mouse Brain

(2020) Yasushi Yabuki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Degradation of Tyrosine Hydroxylase by the Ubiquitin-Proteasome System in the Pathogenesis of Parkinson’s Disease and Dopa-Responsive Dystonia

(2020) Ichiro Kawahata et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Novel fatty acid-binding protein 3 ligand inhibits dopaminergic neuronal death and improves motor and cognitive impairments in Parkinson's disease model mice

(2020) Hidaka Haga et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Extracellular clusterin limits the uptake of α‐synuclein fibrils by murine and human astrocytes

(2020) Alice Filippini et al.   GLIA

Gut-brain axis and the spread of α-synuclein pathology: vagal highway or dead end?

(2019) David P. Breen et al.   MOVEMENT DISORDERS

Inhibition of MPTP-induced α-synuclein oligomerization by fatty acid-binding protein 3 ligand in MPTP-treated mice

(2019) Kazuya Matsuo et al.   NEUROPHARMACOLOGY

Tau interacts with the C-terminal region of α-synuclein, promoting formation of toxic aggregates with distinct molecular conformations

(2019) Anvesh K. R. Dasari et al.   BIOCHEMISTRY

Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP+-Induced Mitochondrial Dysfunction in Cultured Dopaminergic Neurons

(2019) Ichiro Kawahata et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide

(2018) Friederike Zunke et al.   NEURON

C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction

(2018) Janin Lautenschläger et al.   Nature Communications

Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization

(2018) An Cheng et al.   BRAIN RESEARCH

Dopamine or biopterin deficiency potentiates phosphorylation at 40 Ser and ubiquitination of tyrosine hydroxylase to be degraded by the ubiquitin proteasome system

(2015) Ichiro Kawahata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

(2015) W. Peelaerts et al.   NATURE

FABP3 Protein Promotes α-Synuclein Oligomerization Associated with 1-Methyl-1,2,3,6-tetrahydropiridine-induced Neurotoxicity

(2014) Norifumi Shioda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasma Membrane Compartmentalization of D2 Dopamine Receptors

(2013) Meenakshi Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N-terminal region of the dopamine D2 receptor, a rhodopsin-like GPCR, regulates correct integration into the plasma membrane and endocytic routes

(2011) DI Cho et al.   BRITISH JOURNAL OF PHARMACOLOGY

Caveolin-1 interacts with alpha-synuclein and mediates toxic actions of cellular alpha-synuclein overexpression

(2011) Alexandra Madeira et al.   NEUROCHEMISTRY INTERNATIONAL

Caveolin regulation of neuronal intracellular signaling

(2010) Christopher M. Stern et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Brain-specific fatty acid-binding protein is elevated in serum of patients with dementia-related diseases

(2010) C. E. Teunissen et al.   EUROPEAN JOURNAL OF NEUROLOGY

Heart-Type Fatty Acid Binding Protein Regulates Dopamine D2 Receptor Function in Mouse Brain

(2010) N. Shioda et al.   JOURNAL OF NEUROSCIENCE

Fibril Fragmentation Enhances Amyloid Cytotoxicity

(2009) Wei-Feng Xue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accumulation of phosphorylated tyrosine hydroxylase into insoluble protein aggregates by inhibition of an ubiquitin–proteasome system in PC12D cells

(2009) Ichiro Kawahata et al.   JOURNAL OF NEURAL TRANSMISSION

Emotional response in dopamine D2L receptor-deficient mice

(2008) Dubravka Hranilovic et al.   BEHAVIOURAL BRAIN RESEARCH

Fatty Acid Binding Protein: Localization and Functional Significance in the Brain

(2008) Yuji Owada   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE