Critical Role of the Maternal Immune System in the Pathogenesis of Autism Spectrum Disorder
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Critical Role of the Maternal Immune System in the Pathogenesis of Autism Spectrum Disorder
Authors
Keywords
-
Journal
Biomedicines
Volume 8, Issue 12, Pages 557
Publisher
MDPI AG
Online
2020-12-02
DOI
10.3390/biomedicines8120557
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Developmental IL-6 Exposure Favors Production of PDGF-Responsive Multipotential Progenitors at the Expense of Neural Stem Cells and Other Progenitors
- (2020) Ekta Kumari et al. Stem Cell Reports
- Cytokine changes associated with the maternal immune activation (MIA) model of autism: A penalized regression approach
- (2020) Cristina Paraschivescu et al. PLoS One
- Interaction between Maternal Immune Activation and Antibiotic Use during Pregnancy and Child Risk of Autism Spectrum Disorder
- (2020) Calliope Holingue et al. Autism Research
- The prenatal challenge with lipopolysaccharide and polyinosinic:polycytidylic acid disrupts CX3CL1-CX3CR1 and CD200-CD200R signalling in the brains of male rat offspring: a link to schizophrenia-like behaviours
- (2020) Katarzyna Chamera et al. Journal of Neuroinflammation
- In utero exposure to endogenous maternal polyclonal anti-Caspr2 antibody leads to behavioral abnormalities resembling autism spectrum disorder in male mice
- (2020) Ciara Bagnall-Moreau et al. Scientific Reports
- P2X7 receptors drive poly(I:C) induced autism-like behavior in mice
- (2019) Gergely Horváth et al. JOURNAL OF NEUROSCIENCE
- Age-related changes in neuroinflammation and prepulse inhibition in offspring of rats treated with Poly I:C in early gestation
- (2019) Shuang Ding et al. Behavioral and Brain Functions
- Interleukin-1β Disturbs the Proliferation and Differentiation of Neural Precursor Cells in the Hippocampus via Activation of Notch Signaling in Postnatal Rats Exposed to Lipopolysaccharide
- (2019) Qiongyu Lin et al. ACS Chemical Neuroscience
- Antigenic Targets of Patient and Maternal Autoantibodies in Autism Spectrum Disorder
- (2019) Rut Mazón-Cabrera et al. Frontiers in Immunology
- Overview of prospects for inflammation pathways in autism spectrum disorders
- (2019) H. Turbé et al. ENCEPHALE-REVUE DE PSYCHIATRIE CLINIQUE BIOLOGIQUE ET THERAPEUTIQUE
- Maternal immune markers during pregnancy and child neurodevelopmental outcomes at age 20 months in the Seychelles Child Development Study
- (2019) Jessica L. Irwin et al. JOURNAL OF NEUROIMMUNOLOGY
- Identification of the antigenic epitopes of maternal autoantibodies in autism spectrum disorders
- (2018) Elizabeth Edmiston et al. BRAIN BEHAVIOR AND IMMUNITY
- Maternal IL-17A in autism
- (2018) Helen Wong et al. EXPERIMENTAL NEUROLOGY
- Beyond infection - Maternal immune activation by environmental factors, microglial development, and relevance for autism spectrum disorders
- (2018) Staci D. Bilbo et al. EXPERIMENTAL NEUROLOGY
- Maternal autoantibody related autism: mechanisms and pathways
- (2018) Karen L. Jones et al. MOLECULAR PSYCHIATRY
- Autism-specific maternal autoantibodies produce behavioral abnormalities in an endogenous antigen-driven mouse model of autism
- (2018) Karen L. Jones et al. MOLECULAR PSYCHIATRY
- Autism Spectrum Disorder: Classification, diagnosis and therapy
- (2018) Samata R. Sharma et al. PHARMACOLOGY & THERAPEUTICS
- Presence of Segmented Filamentous Bacteria in Human Children and Its Potential Role in the Modulation of Human Gut Immunity
- (2018) Bo Chen et al. Frontiers in Microbiology
- Maternal Gestational Immune Response and Autism Spectrum Disorder Phenotypes at 7 Years of Age in the Seychelles Child Development Study
- (2018) Jessica L. Irwin et al. MOLECULAR NEUROBIOLOGY
- Brain changes in a maternal immune activation model of neurodevelopmental brain disorders
- (2018) Lara Bergdolt et al. PROGRESS IN NEUROBIOLOGY
- Increasing Role of Maternal Immune Activation in Neurodevelopmental Disorders
- (2018) Julie Boulanger-Bertolus et al. Frontiers in Behavioral Neuroscience
- Maternal immune activation, central nervous system development and behavioral phenotypes
- (2018) Elena Minakova et al. Birth Defects Research
- Oxidative and inflammatory mediators are upregulated in neutrophils of autistic children: Role of IL-17A receptor signaling
- (2018) Ahmed Nadeem et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- The Heritability of Autism Spectrum Disorder
- (2017) Sven Sandin et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Preterm birth: Inflammation, fetal injury and treatment strategies
- (2017) Ashley K. Boyle et al. JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- (2017) Theo Vos et al. LANCET
- Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring
- (2017) Sangdoo Kim et al. NATURE
- Transfer of maternal immunity and programming of the newborn immune system
- (2017) Madeleine F. Jennewein et al. Seminars in Immunopathology
- Cellular and molecular mechanisms of viral infection in the human placenta
- (2017) Moises León-Juárez et al. Pathogens and Disease
- Maternal autoimmune antibodies alter the dendritic arbor and spine numbers in the infragranular layers of the cortex
- (2017) Jeanelle Ariza et al. PLoS One
- Maternal autoimmune diseases and the risk of autism spectrum disorders in offspring: A systematic review and meta-analysis
- (2016) Shao-wei Chen et al. BEHAVIOURAL BRAIN RESEARCH
- Maternal infection during pregnancy and risk of autism spectrum disorders: A systematic review and meta-analysis
- (2016) Hai-yin Jiang et al. BRAIN BEHAVIOR AND IMMUNITY
- Autism with intellectual disability is associated with increased levels of maternal cytokines and chemokines during gestation
- (2016) K L Jones et al. MOLECULAR PSYCHIATRY
- The Role of the Immune System in Autism Spectrum Disorder
- (2016) Amory Meltzer et al. NEUROPSYCHOPHARMACOLOGY
- Maternal immune activation: Implications for neuropsychiatric disorders
- (2016) M. L. Estes et al. SCIENCE
- The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
- (2016) G. B. Choi et al. SCIENCE
- Decidual natural killer cells and the immune microenvironment at the maternal-fetal interface
- (2016) Binqing Fu et al. Science China-Life Sciences
- The Interaction between the Immune System and Epigenetics in the Etiology of Autism Spectrum Disorders
- (2016) Stefano Nardone et al. Frontiers in Neuroscience
- Genetic Syndromes, Maternal Diseases and Antenatal Factors Associated with Autism Spectrum Disorders (ASD)
- (2016) Asher Ornoy et al. Frontiers in Neuroscience
- Maternal hospitalization with infection during pregnancy and risk of autism spectrum disorders
- (2015) Brian K. Lee et al. BRAIN BEHAVIOR AND IMMUNITY
- Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells
- (2015) Koji Atarashi et al. CELL
- Maternal Anti-Fetal Brain IgG Autoantibodies and Autism Spectrum Disorder: Current Knowledge and its Implications for Potential Therapeutics
- (2015) Elizabeth Fox-Edmiston et al. CNS DRUGS
- Heritability of autism spectrum disorders: a meta-analysis of twin studies
- (2015) Beata Tick et al. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
- Immune mediators in the brain and peripheral tissues in autism spectrum disorder
- (2015) Myka L. Estes et al. NATURE REVIEWS NEUROSCIENCE
- Family history of autoimmune diseases is associated with an increased risk of autism in children: A systematic review and meta-analysis
- (2015) Shunquan Wu et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- IL-1 Receptor Blockade Prevents Fetal Cortical Brain Injury but Not Preterm Birth in a Mouse Model of Inflammation-Induced Preterm Birth and Perinatal Brain Injury
- (2014) Kirstin Leitner et al. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Understanding the Complexity of the Immune System during Pregnancy
- (2014) Karen Racicot et al. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Embryonic intraventricular exposure to autism-specific maternal autoantibodies produces alterations in autistic-like stereotypical behaviors in offspring mice
- (2014) Jasmin Camacho et al. BEHAVIOURAL BRAIN RESEARCH
- Anti-brain antibodies are associated with more severe cognitive and behavioral profiles in Italian children with Autism Spectrum Disorder
- (2014) I.S. Piras et al. BRAIN BEHAVIOR AND IMMUNITY
- Update on diagnostic classification in autism
- (2014) Bryan H. King et al. CURRENT OPINION IN PSYCHIATRY
- Uterine NK cells: active regulators at the maternal-fetal interface
- (2014) Ashley Moffett et al. JOURNAL OF CLINICAL INVESTIGATION
- Most genetic risk for autism resides with common variation
- (2014) Trent Gaugler et al. NATURE GENETICS
- Patches of Disorganization in the Neocortex of Children with Autism
- (2014) Rich Stoner et al. NEW ENGLAND JOURNAL OF MEDICINE
- Maternal influences on fetal microbial colonization and immune development
- (2014) Joann Romano-Keeler et al. PEDIATRIC RESEARCH
- The epidemiology and global burden of autism spectrum disorders
- (2014) A. J. Baxter et al. PSYCHOLOGICAL MEDICINE
- Regulatory T-Cells in Pregnancy: Historical Perspective, State of the Art, and Burning Questions
- (2014) Maria Grazia Ruocco et al. Frontiers in Immunology
- Brain-Reactive Antibodies and Disease
- (2013) B. Diamond et al. Annual Review of Immunology
- Activation of the Maternal Immune System During Pregnancy Alters Behavioral Development of Rhesus Monkey Offspring
- (2013) Melissa D. Bauman et al. BIOLOGICAL PSYCHIATRY
- Brain-reactive IgG correlates with autoimmunity in mothers of a child with an autism spectrum disorder
- (2013) L Brimberg et al. MOLECULAR PSYCHIATRY
- Recurrence of Autism Spectrum Disorders in Full- and Half-Siblings and Trends Over Time
- (2013) Therese K. Grønborg et al. JAMA Pediatrics
- Autism-specific maternal autoantibodies recognize critical proteins in developing brain
- (2013) D Braunschweig et al. Translational Psychiatry
- Focal cortical dysplasias in autism spectrum disorders
- (2013) Manuel F Casanova et al. Acta Neuropathologica Communications
- Maternal Autoantibodies in Autism
- (2012) Daniel Braunschweig et al. ARCHIVES OF NEUROLOGY
- Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors
- (2012) Hongen Wei et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism
- (2012) Natalia V. Malkova et al. BRAIN BEHAVIOR AND IMMUNITY
- Maternal and fetal antibrain antibodies in development and disease
- (2012) Elizabeth Fox et al. Developmental Neurobiology
- The immune system and developmental programming of brain and behavior
- (2012) Staci D. Bilbo et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Maternal autism-associated IgG antibodies delay development and produce anxiety in a mouse gestational transfer model
- (2012) Daniel Braunschweig et al. JOURNAL OF NEUROIMMUNOLOGY
- Elevated serum levels of interleukin-17A in children with autism
- (2012) Laila Yousef AL-Ayadhi et al. Journal of Neuroinflammation
- Cytokine dysregulation in autism spectrum disorders (ASD): Possible role of the environment
- (2012) Paula E. Goines et al. NEUROTOXICOLOGY AND TERATOLOGY
- Autism After Infection, Febrile Episodes, and Antibiotic Use During Pregnancy: An Exploratory Study
- (2012) H. O. Atladottir et al. PEDIATRICS
- Modeling an autism risk factor in mice leads to permanent immune dysregulation
- (2012) E. Y. Hsiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism
- (2011) Joachim Hallmayer ARCHIVES OF GENERAL PSYCHIATRY
- IgG Placental Transfer in Healthy and Pathological Pregnancies
- (2011) Patricia Palmeira et al. Clinical & Developmental Immunology
- Exposure of foetal neural progenitor cells to IL-1β impairs their proliferation and alters their differentiation - a role for maternal inflammation?
- (2011) Sean J. Crampton et al. JOURNAL OF NEUROCHEMISTRY
- IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation
- (2011) Hongen Wei et al. Journal of Neuroinflammation
- Maternal Immune Activation and Autism Spectrum Disorder: Interleukin-6 Signaling as a Key Mechanistic Pathway
- (2011) E. Carla Parker-Athill et al. NEUROSIGNALS
- Plasma Cytokine Profiles in Subjects with High-Functioning Autism Spectrum Disorders
- (2011) Katsuaki Suzuki et al. PLoS One
- Maternal infection and immune involvement in autism
- (2011) Paul H. Patterson TRENDS IN MOLECULAR MEDICINE
- Amniotic fluid inflammatory cytokines: Potential markers of immunologic dysfunction in autism spectrum disorders
- (2011) Morsi W. Abdallah et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
- Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study
- (2011) Paula E Goines et al. Molecular Autism
- The Immune System in Pregnancy: A Unique Complexity
- (2010) Gil Mor et al. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Autoantibodies to cerebellum in children with autism associate with behavior
- (2010) Paula Goines et al. BRAIN BEHAVIOR AND IMMUNITY
- Activation of the maternal immune system induces endocrine changes in the placenta via IL-6
- (2010) Elaine Y. Hsiao et al. BRAIN BEHAVIOR AND IMMUNITY
- Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome
- (2010) Paul Ashwood et al. BRAIN BEHAVIOR AND IMMUNITY
- Etiological heterogeneity in autism spectrum disorders: More than 100 genetic and genomic disorders and still counting
- (2010) Catalina Betancur BRAIN RESEARCH
- The immune systemʼs role in the biology of autism
- (2010) Paula Goines et al. CURRENT OPINION IN NEUROLOGY
- Longitudinal modulation of immune system cytokine profile during pregnancy
- (2010) Jeffrey M. Denney et al. CYTOKINE
- Parental Autoimmune Diseases Associated With Autism Spectrum Disorders in Offspring
- (2010) Alexander Keil et al. EPIDEMIOLOGY
- IL-1 Receptor Antagonist Protects against Placental and Neurodevelopmental Defects Induced by Maternal Inflammation
- (2010) S. Girard et al. JOURNAL OF IMMUNOLOGY
- Differential monocyte responses to TLR ligands in children with autism spectrum disorders
- (2009) Amanda M. Enstrom et al. BRAIN BEHAVIOR AND IMMUNITY
- Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria
- (2009) Ivaylo I. Ivanov et al. CELL
- The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders
- (2009) Pat Levitt et al. JOURNAL OF CLINICAL INVESTIGATION
- Prenatal exposure to antibodies from mothers of children with autism produces neurobehavioral alterations: A pregnant dam mouse model
- (2009) Harvey S. Singer et al. JOURNAL OF NEUROIMMUNOLOGY
- Association of Family History of Autoimmune Diseases and Autism Spectrum Disorders
- (2009) H. O. Atladottir et al. PEDIATRICS
- Early-life programming of later-life brain and behavior: a critical role for the immune system
- (2009) Staci D. Bilbo Frontiers in Behavioral Neuroscience
- Abnormalities of IGF-I signaling in the pathogenesis of diseases of the bone, brain, and fetoplacental unit in humans
- (2008) Luigi Laviola et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Maternal Mid-Pregnancy Autoantibodies to Fetal Brain Protein: The Early Markers for Autism Study
- (2008) Lisa A. Croen et al. BIOLOGICAL PSYCHIATRY
- Stereotypies and hyperactivity in rhesus monkeys exposed to IgG from mothers of children with autism
- (2008) Loren A. Martin et al. BRAIN BEHAVIOR AND IMMUNITY
- Antibodies against fetal brain in sera of mothers with autistic children
- (2008) Harvey S. Singer et al. JOURNAL OF NEUROIMMUNOLOGY
- Neuroanatomy of autism
- (2008) David G. Amaral et al. TRENDS IN NEUROSCIENCES
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started