Advances in Cardiovascular Biomarker Discovery

Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

(2020) Salim S. Virani et al.   CIRCULATION

Role of Sfrps in cardiovascular disease

(2020) Anqing Huang et al.   Therapeutic Advances in Chronic Disease

Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling

(2020) Crystal M. Ghantous et al.   Oxidative Medicine and Cellular Longevity

Discovery of plasma biomarkers for predicting the severity of coronary artery atherosclerosis by quantitative proteomics

(2020) Eu Jeong Ku et al.   BMJ Open Diabetes Research & Care

Targeting the mitogen-activated protein kinase-mediated vascular smooth muscle cell remodeling by angiotensin II

(2020) Masanori Yoshizumi et al.   Annals of Translational Medicine

Inhibition of Src activation reverses pulmonary vascular remodeling in experimental pulmonary arterial hypertension via Akt/mTOR/HIF-1 signaling pathway

(2019) Pengfei Liu et al.   EXPERIMENTAL CELL RESEARCH

Ion Channels and Vascular Diseases

(2019) Jun Cheng et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of serum amyloid A in atherosclerosis

(2019) Preetha Shridas et al.   CURRENT OPINION IN LIPIDOLOGY

Integration of Metabolomic and Other Omics Data in Population-Based Study Designs: An Epidemiological Perspective

(2019) Su Chu et al.   Metabolites

The Role of Vascular Smooth Muscle Cells in Arterial Remodeling: Focus on Calcification-Related Processes

(2019) Armand Jaminon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Serum amyloid a protein as a potential biomarker in predicting acute onset and association with in-hospital death in acute aortic dissection

(2019) Yuchen He et al.   BMC Cardiovascular Disorders

Vascular Smooth Muscle Remodeling in Conductive and Resistance Arteries in Hypertension

(2018) Isola A.M. Brown et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Particulate and gaseous pollutants on inflammation, thrombosis, and autonomic imbalance in subjects at risk for cardiovascular disease

(2017) Szu-Ying Chen et al.   ENVIRONMENTAL POLLUTION

Exosomes as agents of change in the cardiovascular system

(2017) A.J. Poe et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Analysis of circulating microRNAs in patients with repaired Tetralogy of Fallot with and without heart failure

(2017) Masood Abu-Halima et al.   Journal of Translational Medicine

Extracellular vesicles-mediated transfer of miR-208a/b exaggerate hypoxia/reoxygenation injury in cardiomyocytes by reducing QKI expression

(2017) Feng Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

MicroRNAs Association in the Cardiac Hypertrophy Secondary to Complex Congenital Heart Disease in Children

(2017) Ma. C. Sánchez-Gómez et al.   PEDIATRIC CARDIOLOGY

Endothelial miRNAs as Cellular Messengers in Cardiometabolic Diseases

(2017) Makon-Sébastien Njock et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Exosomes: Origins and Therapeutic Potential for Neurodegenerative Disease

(2017) Diana K. Sarko et al.   Frontiers in Neuroscience

Increased Circulating Exosomal miRNA-223 Is Associated with Acute Ischemic Stroke

(2017) Yajing Chen et al.   Frontiers in Neurology

Exosomes in Cancer Diagnostics

(2017) Young Soung et al.   Cancers

Molecular Ultrasound Imaging of Junctional Adhesion Molecule A Depicts Acute Alterations in Blood Flow and Early Endothelial Dysregulation

(2017) Adelina Curaj et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proteomic footprint of myocardial ischemia/reperfusion injury: Longitudinal study of the at-risk and remote regions in the pig model

(2017) Aleksandra Binek et al.   Scientific Reports

microRNAs in lipoprotein metabolism and cardiometabolic disorders

(2016) Noemi Rotllan et al.   ATHEROSCLEROSIS

State of the Art: Blood Biomarkers for Risk Stratification in Patients with Stable Ischemic Heart Disease

(2016) Torbjørn Omland et al.   CLINICAL CHEMISTRY

Endothelium-Derived Hyperpolarizing Factors: A Potential Therapeutic Target for Vascular Dysfunction in Obesity and Insulin Resistance

(2016) Guanghong Jia et al.   DIABETES

Caveolin-1 Deletion Prevents Hypertensive Vascular Remodeling Induced by Angiotensin IINovelty and Significance

(2016) Steven J. Forrester et al.   HYPERTENSION

Proteomic identification of putative biomarkers for early detection of sudden cardiac death in a family with a LMNA gene mutation causing dilated cardiomyopathy

(2016) Irene Izquierdo et al.   Journal of Proteomics

Plasma-derived Extracellular Vesicles Contain Predictive Biomarkers and Potential Therapeutic Targets for Myocardial Ischemic (MI) Injury

(2016) Esther Sok Hwee Cheow et al.   MOLECULAR & CELLULAR PROTEOMICS

miR-22-5p revealed as a potential biomarker involved in the acute phase of myocardial infarction via profiling of circulating microRNAs

(2016) Agata Maciejak et al.   Molecular Medicine Reports

Advances in quadrupole and time-of-flight mass spectrometry for peptide MRM based translational research analysis

(2016) Richard J. Mbasu et al.   PROTEOMICS

Adiponectin Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Remodeling through Nitric Oxide and the RhoA/ROCK Pathway

(2016) Wared Nour-Eldine et al.   Frontiers in Pharmacology

Calcineurin/NFAT Activation-Dependence of Leptin Synthesis and Vascular Growth in Response to Mechanical Stretch

(2016) Nadia Soudani et al.   Frontiers in Physiology

Aberrant Glycosylation in the Left Ventricle and Plasma of Rats with Cardiac Hypertrophy and Heart Failure

(2016) Chiaki Nagai-Okatani et al.   PLoS One

Urinary Proteomics Pilot Study for Biomarker Discovery and Diagnosis in Heart Failure with Reduced Ejection Fraction

(2016) Kasper Rossing et al.   PLoS One

Expression of Plasma microRNA-1/21/ 208a/499 in Myocardial Ischemic Reperfusion Injury

(2015) Wei Yang et al.   CARDIOLOGY

Biomarkers, Risk Factors, and Risk

(2015) Harlan M. Krumholz  

Blood-based microRNA signatures differentiate various forms of cardiac hypertrophy

(2015) Anselm A. Derda et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Differential Role of Leptin and Adiponectin in Cardiovascular System

(2015) C. M. Ghantous et al.   International Journal of Endocrinology

Biomarkers, Risk Factors, and Risk

(2015) Harlan M. Krumholz   Circulation-Cardiovascular Quality and Outcomes

Serum cyclin-dependent kinase 9 is a potential biomarker of atherosclerotic inflammation

(2015) Yeming Han et al.   Oncotarget

Tetranectin as a Potential Biomarker for Stable Coronary Artery Disease

(2015) Yanjia Chen et al.   Scientific Reports

Endogenous Ouabain: An Old Cardiotonic Steroid as a New Biomarker of Heart Failure and a Predictor of Mortality after Cardiac Surgery

(2015) Marco Simonini et al.   Biomed Research International

Mechanical stretch-induced vascular hypertrophy occurs through modulation of leptin synthesis-mediated ROS formation and GATA-4 nuclear translocation

(2015) Crystal M. Ghantous et al.   Frontiers in Pharmacology

miR-26a Linked to Pulmonary Hypertension by Global Assessment of Circulating Extracellular MicroRNAs

(2014) Kenny Schlosser et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Increased arterial stiffness in resistant hypertension is associated with inflammatory biomarkers

(2014) Natália Ruggeri Barbaro et al.   BLOOD PRESSURE

Prevalence and costs of treating uncomplicated stage 1 hypertension in primary care: a cross-sectional analysis

(2014) James P Sheppard et al.   BRITISH JOURNAL OF GENERAL PRACTICE

Exosomal miRNAs as potential biomarkers of cardiovascular risk in children

(2014) Abdelnaby Khalyfa et al.   Journal of Translational Medicine

C-Reactive Protein in Human Atherogenesis: Facts and Fiction

(2014) Oliver Zimmermann et al.   MEDIATORS OF INFLAMMATION

MiRNAs as Biomarkers of Myocardial Infarction: A Meta-Analysis

(2014) Chao Cheng et al.   PLoS One

Serum Levels of Soluble ICAM-1 in Children with Pulmonary Artery Hypertension

(2014) Melahat Melek Oguz et al.   TEXAS HEART INSTITUTE JOURNAL

Adiponectin Levels and the Risk of Hypertension

(2013) Dae Hyun Kim et al.   HYPERTENSION

C-reactive protein and Hypertension

(2013) F G Hage   JOURNAL OF HUMAN HYPERTENSION

The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure

(2013) E. T. Askevold et al.   JOURNAL OF INTERNAL MEDICINE

Molecular Mechanisms of Hypertension—Reactive Oxygen Species and Antioxidants: A Basic Science Update for the Clinician

(2012) Augusto C. Montezano et al.   CANADIAN JOURNAL OF CARDIOLOGY

Renin and prorenin as biomarkers in hypertension

(2012) A.H. Jan Danser   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Uric Acid Level and Elevated Blood Pressure in US Adolescents

(2012) Lauren F. Loeffler et al.   HYPERTENSION

Hydrophobic Imbalance in the Cytoplasmic Domain of Phospholamban Is a Determinant for Lethal Dilated Cardiomyopathy

(2012) Delaine K. Ceholski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-circulating leptin levels are associated with increased blood pressure in uncontrolled resistant hypertension

(2012) C de Haro Moraes et al.   JOURNAL OF HUMAN HYPERTENSION

Small but smart--microRNAs in the centre of inflammatory processes during cardiovascular diseases, the metabolic syndrome, and ageing

(2011) B. Schroen et al.   CARDIOVASCULAR RESEARCH

Analytical Characteristics of High-Sensitivity Cardiac Troponin Assays

(2011) F. S. Apple et al.   CLINICAL CHEMISTRY

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel biomarkers in cardiovascular disease: Update 2010

(2010) Willibald Hochholzer et al.   AMERICAN HEART JOURNAL

Levels of asymmetrical dimethylarginine are predictive of brachial artery flow-mediated dilation 6 years later. The Cardiovascular Risk in Young Finns Study

(2010) Hannu Päivä et al.   ATHEROSCLEROSIS

From endothelial dysfunction to atherosclerosis

(2010) S. Sitia et al.   AUTOIMMUNITY REVIEWS

Circulating MicroRNA-208b and MicroRNA-499 Reflect Myocardial Damage in Cardiovascular Disease

(2010) Maarten F. Corsten et al.   Circulation-Cardiovascular Genetics

Identification of miR-130a, miR-27b and miR-210 as serum biomarkers for atherosclerosis obliterans

(2010) Tianrun Li et al.   CLINICA CHIMICA ACTA

Mechanism and Clinical Significance of the Prothrombotic State in Patients With Essential Hypertension

(2010) Ping Yang et al.   CLINICAL CARDIOLOGY

Vascular Endothelial Function and Hypertension: Insights and Directions

(2010) Kodlipet Dharmashankar et al.   CURRENT HYPERTENSION REPORTS

Myeloperoxidase level in patients with stable coronary artery disease and acute coronary syndromes

(2010) G. Ndrepepa et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Positive Relationship Between Plasma Leptin Level and Hypertension

(2010) Anoop Shankar et al.   HYPERTENSION

Inflammation, Immunity, and Hypertension

(2010) David G. Harrison et al.   HYPERTENSION

Reactive oxygen species and vascular biology: implications in human hypertension

(2010) Rhian M Touyz et al.   HYPERTENSION RESEARCH

Myeloperoxidase and C-Reactive Protein Have Combined Utility for Long-Term Prediction of Cardiovascular Mortality After Coronary Angiography

(2010) Claire L. Heslop et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Peripheral Artery Disease: Current Insight Into the Disease and Its Diagnosis and Management

(2010) Jeffrey W. Olin et al.   MAYO CLINIC PROCEEDINGS

Leptin, Not Adiponectin, Predicts Hypertension in the Copenhagen City Heart Study

(2009) C. Asferg et al.   AMERICAN JOURNAL OF HYPERTENSION

Inflammatory cytokines in vascular dysfunction and vascular disease

(2009) Alexander H. Sprague et al.   BIOCHEMICAL PHARMACOLOGY

Endothelium-dependent contractions and endothelial dysfunction in human hypertension

(2009) Daniele Versari et al.   BRITISH JOURNAL OF PHARMACOLOGY

B-Type Natriuretic Peptides and Cardiovascular Risk

(2009) Emanuele Di Angelantonio et al.   CIRCULATION

MicroRNA Regulation of Cardiovascular Development

(2009) Kimberly R. Cordes et al.   CIRCULATION RESEARCH

Plasma miR-208 as a Biomarker of Myocardial Injury

(2009) X. Ji et al.   CLINICAL CHEMISTRY

Cellular and molecular effects of mechanical stretch on vascular cells and cardiac myocytes

(2009) Kou-Gi Shyu   CLINICAL SCIENCE

p21-Activated Kinase 1 Participates in Vascular Remodeling In Vitro and In Vivo

(2009) Akinari Hinoki et al.   HYPERTENSION

Diagnostic Biomarkers of Essential Arterial Hypertension

(2009) Agnieszka M. Kuklinska et al.   International Heart Journal

Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer

(2009) Zhaohui Huang et al.   INTERNATIONAL JOURNAL OF CANCER

Utility of rapid D-dimer measurement for screening of acute cardiovascular disease in the emergency setting

(2009) Yukichi Tokita et al.   Journal of Cardiology

Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection

(2009) A. Zernecke et al.   Science Signaling

Usefulness of haptoglobin and serum amyloid A proteins as biomarkers for atherothrombotic ischemic stroke diagnosis confirmation

(2008) David Brea et al.   ATHEROSCLEROSIS

Adiponectin protects against myocardial ischaemia-reperfusion injury via AMP-activated protein kinase, Akt, and nitric oxide

(2008) A. T. Gonon et al.   CARDIOVASCULAR RESEARCH

Role of microRNAs in vascular diseases, inflammation, and angiogenesis

(2008) C. Urbich et al.   CARDIOVASCULAR RESEARCH

Hydralazine reduces leukocyte migration through different mechanisms in spontaneously hypertensive and normotensive rats

(2008) Stephen F. Rodrigues et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Endothelium-dependent contractions: when a good guy turns bad!

(2008) Paul M. Vanhoutte et al.   JOURNAL OF PHYSIOLOGY-LONDON

Detection of microRNA Expression in Human Peripheral Blood Microvesicles

(2008) Melissa Piper Hunter et al.   PLoS One

Secondary hypertension: Current diagnosis and treatment

(2007) Jun R. Chiong et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY