Article
Health Care Sciences & Services
Jennifer R. Lyden, Stanley Xu, Komal J. Narwaney, Jason M. Glanz, Ingrid A. Binswanger
Summary: Individuals prescribed long-term opioid therapy (LTOT) are at increased risk of readmission and death after hospital discharge, and the risk of opioid overdose during the immediate post-discharge period is unknown. This study aimed to examine the association between time since hospital discharge and opioid overdose among individuals prescribed LTOT. The results showed that individuals prescribed LTOT appear to be at elevated risk for opioid overdose during the first 7 days after hospital discharge.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Medicine, General & Internal
Tea Rosic, Gillian Kolla, Pamela Leece, Sophie Kitchen, Tara Gomes
Summary: Rates of opioid-related deaths are increasing among youths in Ontario, Canada while the use of opioid agonist treatment (OAT) is declining. Further investigation is needed to understand the reasons behind these trends and to optimize care for youths who use substances.
Article
Psychiatry
Bradley Watts, Daniel J. Gottlieb, Natalie B. Riblet, Jiang Gui, Brian Shiner
Summary: Medication treatment for opioid use disorder (MOUD) has been shown to significantly reduce the risk of suicide mortality as well as external causes of mortality and all-cause mortality.
AMERICAN JOURNAL OF PSYCHIATRY
(2022)
Article
Orthopedics
Nathan H. Varady, Eric L. Smith, Samuel J. Clarkson, Ruijia Niu, David M. Freccero, Antonia F. Chen
Summary: This retrospective cohort study found that patients undergoing outpatient total knee arthroplasty were less likely to become persistent opioid users compared to inpatient patients, even when controlling for patient factors.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2021)
Article
Immunology
Mark W. Tenforde, Jessie Chung, Emily R. Smith, H. Keipp Talbot, Christopher H. Trabue, Richard K. Zimmerman, Fernanda P. Silveira, Manjusha Gaglani, Kempapura Murthy, Arnold S. Monto, Emily T. Martin, Huong Q. McLean, Edward A. Belongia, Lisa A. Jackson, Michael L. Jackson, Jill M. Ferdinands, Brendan Flannery, Manish M. Patel
Summary: This study compared the effectiveness of influenza vaccination between inpatient and outpatient networks in the US, finding that inpatients were older and had more high-risk conditions than outpatients. The overall vaccine effectiveness across seasons was 31% for outpatients and 36% for inpatients, with some differences observed in strain-specific VE between the two groups.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Yu-Jung Jenny Wei, Cheng Chen, Ting-Yuan David Cheng, Siegfried O. Schmidt, Roger B. Fillingim, Almut G. Winterstein
Summary: This study examines the association between incident injury after prescription opioid initiation and the subsequent risk of opioid-related adverse events (ORAEs) among older adults. The findings indicate that injury after starting opioid therapy is associated with an increased risk of ORAEs, especially among patients with injury in the month before starting medication.
Article
Pharmacology & Pharmacy
Marissa Waterloo, Matthew Rozic, Gionna Knauss, Simran Jackson, Dellon Karuga, David E. Zimmerman, Courtney A. Montepara, Jordan R. Covvey, Branden D. Nemecek
Summary: The study aimed to characterize the prescribing patterns of gabapentin for inpatients, showing differences in indication and starting dose between surgical and nonsurgical patients.
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
(2022)
Article
Psychiatry
Isabella Berardelli, Salvatore Sarubbi, Elena Rogante, Denise Erbuto, Mariarosaria Cifrodelli, Carlotta Giuliani, Giuseppa Calabro, David Lester, Marco Innamorati, Maurizio Pompili
Summary: This study found that assessing risk factors in psychiatric hospitalized patients and implementing specialized prevention strategies can reduce subsequent re-hospitalizations. Predictive factors for re-hospitalization include previous hospitalizations, history of suicide attempts, age at onset, and length of stay.
Article
Orthopedics
Alexander S. Guareschi, Josef K. Eichinger, Richard J. Friedman
Summary: This study compared the outcomes of outpatient revision total shoulder arthroplasty (TSA) to inpatient revision TSA and outpatient primary TSA. The results showed that outpatient revision TSA had higher complication rates, readmission, and reoperation rates compared to outpatient primary TSA. However, there was no increased risk of complications, readmission, or reoperation for outpatient revision TSA compared to inpatient revision TSA.
JOURNAL OF SHOULDER AND ELBOW SURGERY
(2023)
Article
Geriatrics & Gerontology
Federica Conti, Dario Consonni, Sarah Damanti, Alessandro Nobili, Luca Pasina, Pier Mannuccio Mannucci, Matteo Cesari, Paolo Dionigi Rossi
Summary: This study aimed to investigate the initiation of psycholeptic drugs in hospitalized older patients, revealing that cognitive impairment was the main risk factor for starting psycholeptic medications. The majority of patients continued to use psycholeptics after hospital discharge.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Health Care Sciences & Services
L. Madeline Mccrary, Kate E. Roberts, Mary Catherine Bowman, Briana Castillo, Jama M. Darling, Christine Dunn, Robyn Jordan, Jane E. Young, Asher J. Schranz
Summary: This study aimed to improve retention in hepatitis C (HCV) care among hospitalized people who inject drugs (PWID). The program, which included e-consultation-prompted care coordination and outpatient telehealth for HCV treatment, achieved favorable outcomes for hospitalized PWID.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Clinical Neurology
Adeolu Funso Oladunjoye, Syed Zane Kaleem, Aishwarya Suresh, Vikram Sahni, Matthew J. Thoonkuzhy, Gibson Anugwom, Olubunmi Oladunjoye, David Otuada, Joseph Ikekwere, Eduardo D. Espiridion
Summary: This study used data from BD hospitalizations to investigate the association between Cannabis Use Disorder (CUD) and medication nonadherence in patients with Bipolar Disorder. The research found a significant relationship between CUD and medication noncompliance among BD patients, highlighting the importance of collaboration between psychiatric and addiction services in improving patient outcomes.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Isabel Pavao Martins, Ana Catarina Fonseca, Luisa Pires, Jose M. Ferro
Summary: The study compared the impact of neurology outpatient versus inpatient rotation settings on medical student grades and found that students assigned to the ward achieved significantly higher grades in both practical and multiple choice exams. The teaching setting was identified as an independent predictor of student performance, suggesting the importance of a balanced distribution of students across different clinical settings.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Review
Otorhinolaryngology
Daniel A. Benito, Luke J. Pasick, Daniel Bestourous, Punam Thakkar, Joseph F. Goodman, Arjun S. Joshi
Summary: The study aimed to compare complications between outpatient and inpatient parotidectomy, and found that outpatient parotidectomy may be as safe as inpatient parotidectomy in appropriately selected patients.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Article
Psychology, Clinical
Noa Krawczyk, Arthur Robin Williams, Brendan Saloner, Magdalena Cerda
Summary: The study revealed that in outpatient settings, some episodes of MOUD treatment are discontinued within six months, with the strongest risk factors for discontinuation being younger age, homelessness, co-use of methamphetamine, and referral to treatment by criminal justice or other sources.
JOURNAL OF SUBSTANCE ABUSE TREATMENT
(2021)
Article
Substance Abuse
Shayla Nolen, Xiao Zang, Avik Chatterjee, Czarina N. Behrends, Traci C. Green, Aranshi Kumar, Benjamin P. Linas, Jake R. Morgan, Sean M. Murphy, Alexander Y. Walley, Shapei Yan, Bruce R. Schackman, Brandon D. L. Marshall
Summary: The study found no racial/ethnic inequities in naloxone distribution at the municipal level in Rhode Island and Massachusetts, USA. Naloxone coverage ratios did not vary significantly among municipalities with different percentages of non-white residents in the multivariable analysis. However, a secondary analysis revealed that municipalities with higher percentages of African American/black residents had higher naloxone coverage ratios.
Article
Substance Abuse
Avik Chatterjee, Shapei Yan, Ziming Xuan, Katherine M. Waye, Audrey M. Lambert, Traci C. Green, Thomas J. Stopka, Robin A. Pollini, Jake R. Morgan, Alexander Y. Walley
Summary: The study found that the quantity and coverage of naloxone dispensed under NSO increased annually, but communities with higher percentages of Hispanic populations and rural characteristics were less likely to dispense naloxone under NSO.
DRUG AND ALCOHOL DEPENDENCE
(2022)
Article
Health Care Sciences & Services
Jake R. Morgan, Emily K. Quinn, Christine E. Chaisson, Elizabeth Ciemins, Nikita Stempniewicz, Laura F. White, Benjamin P. Linas, Alexander Y. Walley, Marc R. LaRochelle
Summary: This study aims to investigate the association between individuals with opioid use disorder and the cost-sharing for medication, and the results show that only the medical services deductible is associated with MOUD initiation.
Article
Substance Abuse
Alexandra Savinkina, Rajapaksha W. M. A. Madushani, Golnaz Eftekhari Yazdi, Jianing Wang, Joshua A. Barocas, Jake R. Morgan, Sabrina A. Assoumou, Alexander Y. Walley, Benjamin P. Linas, Sean M. Murphy
Summary: Initiating medications for opioid use disorder and implementing linkage policies among detox patients in Massachusetts can effectively prevent fatal opioid overdoses and are cost-effective.
Article
Gastroenterology & Hepatology
Jake R. Morgan, Elizabeth Marsh, Alexandra Savinkina, Sonjelle Shilton, Shaun Shadaker, Tengiz Tsertsvadze, George Kamkamidze, Maia Alkhazashvili, Timothy Morgan, Pam Belperio, Lisa Backus, Waheed Doss, Gamal Esmat, Mohamed Hassany, Aisha Elsharkawy, Wafaa Elakel, Mai Mehrez, Graham R. Foster, Constance Wose Kinge, Kara W. Chew, Charles S. Chasela, Ian M. Sanne, Yin M. Thanung, Anne Loarec, Khawar Aslam, Suna Balkan, Philippa J. Easterbrook, Benjamin P. Linas
Summary: To achieve global elimination of hepatitis C virus, scaling up testing is necessary. Point-of-care HCV viral load assays can facilitate testing in hard-to-reach or marginalized populations. This study aimed to determine an acceptable lower limit of detection (LLoD) for detectable HCV viremia as a test for cure. Data from multiple countries and clinical trial registries were analyzed, and it was found that an assay with a detection level of 1000 IU/mL or higher may miss some patients with low-level treatment failure.
JOURNAL OF VIRAL HEPATITIS
(2022)
Article
Medicine, Research & Experimental
Jason S. Haukoos, Sarah E. Rowan, James W. Galbraith, Richard E. Rothman, Yu-Hsiang Hsieh, Emily Hopkins, Rachel A. Houk, Matthew F. Toerper, Kevin F. Kamis, Jake R. Morgan, Benjamin P. Linas, Alia A. Al-Tayyib, Edward M. Gardner, Michael S. Lyons, Allison L. Sabel, Douglas A. E. White, David L. Wyles
Summary: This article describes a trial that aims to evaluate the comparative effectiveness of non-targeted and targeted HCV screening in emergency departments. The trial will be conducted in three ED centers and will include observational studies to assess cost effectiveness, disparities, and social determinants of health in screening, linkage-to-care, and treatment for HCV.
Editorial Material
Substance Abuse
Jake R. Morgan, Marc R. LaRochelle
Article
Public, Environmental & Occupational Health
Jake R. Morgan, Sean M. Murphy, Sabrina A. Assoumou, Benjamin P. Linas
Summary: This study aimed to estimate absenteeism due to substance use disorder among full-time employees. The results showed a positive association between substance use and absenteeism, highlighting the importance for employers to promote treatment programs for employees in order to reduce the costs associated with absenteeism and turnover.
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2022)
Article
Medicine, General & Internal
Carl G. Streed, Jake R. Morgan, Mam Jarra Gai, Marc R. Larochelle, Michael K. Paasche-Orlow, Jessica L. Taylor
Summary: This study aimed to estimate the uptake of HIV preexposure prophylaxis (PrEP) among commercially insured individuals with opioid or stimulant use disorder, based on injection drug use (IDU) status. The results showed that HIV PrEP delivery remained low and should be offered alongside substance use disorder treatment and other HIV prevention services.
Article
Oncology
Yeon Woo Lee, Jake R. Morgan, Stephen Fiascone, Rebecca B. Perkins
Summary: This study investigated rates of under- and overscreening for cervical cancer in a national cohort. The results showed that only 18.1% of women received guideline-adherent screening, and 25.4% were unscreened during the 6-year period. Younger women were more likely to be overscreened, while older women were more likely to be underscreened or unscreened. Additional strategies are needed to improve guideline-adherent care for cervical cancer screening.
GYNECOLOGIC ONCOLOGY
(2022)
Article
Substance Abuse
Shayla Nolen, Xiao Zang, Avik Chatterjee, Czarina N. Behrends, Traci C. Green, Benjamin P. Linas, Jake R. Morgan, Sean M. Murphy, Alexander Y. Walley, Bruce R. Schackman, Brandon D. L. Marshall
Summary: This study reveals racial/ethnic inequities in the access to naloxone in Massachusetts, with minority groups having lower distribution rates compared to white residents. Moreover, naloxone distribution is more likely to occur in racially segregated communities.
DRUG AND ALCOHOL DEPENDENCE
(2022)
Editorial Material
Emergency Medicine
Jake R. Morgan, Sabrina A. Assoumou
ACADEMIC EMERGENCY MEDICINE
(2023)
Article
Substance Abuse
Xiao Zang, Alexander Y. Walley, Avik Chatterjee, Simeon D. Kimmel, Jake R. Morgan, Sean M. Murphy, Benjamin P. Linas, Shayla Nolen, Brittni Reilly, Catherine Urquhart, Bruce R. Schackman, Brandon D. L. Marshall
Summary: The COVID-19 pandemic has led to a significant increase in opioid overdose deaths in Massachusetts, particularly among racial and ethnic minority communities. We compared the impact of the pandemic on opioid overdose fatalities and naloxone distribution across different racial and ethnic groups in the state.
Article
Health Care Sciences & Services
Avik Chatterjee, Shapei Yan, Audrey Lambert, Jake R. Morgan, Traci C. Green, Philip J. Jeng, Ali Jalali, Ziming Xuan, Maxwell Krieger, Brandon D. L. Marshall, Alexander Y. Walley, Sean M. Murphy
Summary: This study compared different datasets with the commercially available pharmacy national claims dataset in Massachusetts, Rhode Island, and New York City. The results showed that Symphony's data exceeded the local datasets, except in Rhode Island after legislation required reporting to PDMP.
HEALTH SERVICES RESEARCH
(2023)
Meeting Abstract
Substance Abuse
Tae Woo Park, Tithi Baul, Jake Morgan, Timothy Wilens, Amy Yule
AMERICAN JOURNAL ON ADDICTIONS
(2022)