Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer
Published 2020 View Full Article
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Title
Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer
Authors
Keywords
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Journal
Biomolecules
Volume 10, Issue 12, Pages 1686
Publisher
MDPI AG
Online
2020-12-17
DOI
10.3390/biom10121686
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Note: Only part of the references are listed.- SETD3 acts as a prognostic marker in breast cancer patients and modulates the viability and invasion of breast cancer cells
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- Histone methyltransferase SMYD2 selective inhibitor LLY-507 in combination with poly ADP ribose polymerase inhibitor has therapeutic potential against high-grade serous ovarian carcinomas
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- Histone methyltransferase KMT5A gene modulates oncogenesis and lipid metabolism of papillary thyroid cancer in�vitro
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- Integrated Genomic, Epigenomic, and Expression Analyses of Ovarian Cancer Cell Lines
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- Oncogenic histone methyltransferase EZH2: A novel prognostic marker with therapeutic potential in endometrial cancer
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- Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivity
- (2017) Ozge Gursoy-Yuzugullu et al. Oncotarget
- miR-502 medaited histone methyltransferase SET8 expression is associated with outcome of esophageal squamous cell carcinoma
- (2016) Cuiju Wang et al. Scientific Reports
- SET8 expression is associated with overall survival in gastric cancer
- (2015) X.L. Shi et al. GENETICS AND MOLECULAR RESEARCH
- SET8 induces epithelial-mesenchymal transition and enhances prostate cancer cell metastasis by cooperating with ZEB1
- (2015) LIEJUN HOU et al. Molecular Medicine Reports
- Histone H4 Lys 20 methyltransferase SET8 promotes androgen receptor-mediated transcription activation in prostate cancer
- (2014) Lushuai Yao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8
- (2014) Anqi Ma et al. JOURNAL OF MEDICINAL CHEMISTRY
- Critical role of lysine 134 methylation on histone H2AX for γ-H2AX production and DNA repair
- (2014) Kenbun Sone et al. Nature Communications
- Dynamic Methylation of Numb by Set8 Regulates Its Binding to p53 and Apoptosis
- (2013) Gurpreet Kaur Dhami et al. MOLECULAR CELL
- Histone Lysine Methyltransferase SETD8 Promotes Carcinogenesis by Deregulating PCNA Expression
- (2012) M. Takawa et al. CANCER RESEARCH
- Histone lysine methylation and demethylation pathways in cancer
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- Ovarian Cancer Pathogenesis: A Model in Evolution
- (2009) Alison M. Karst et al. Journal of Oncology
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