Optimising Vaccine Dose in Inoculation against SARS-CoV-2, a Multi-Factor Optimisation Modelling Study to Maximise Vaccine Safety and Efficacy

Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial

(2020) Feng-Cai Zhu et al.   LANCET

Immunologic Dose-Response to Adenovirus-Vectored Vaccines in Animals and Humans: A Systematic Review of Dose-Response Studies of Replication Incompetent Adenoviral Vaccine Vectors when Given via an Intramuscular or Subcutaneous Route

(2020) Sara Afrough et al.   Vaccines

Response Type and Host Species may be Sufficient to Predict Dose-Response Curve Shape for Adenoviral Vector Vaccines

(2020) John Benest et al.   Vaccines

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): a global pandemic and treatment strategies

(2020) Atul Sharma et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Herd immunity – estimating the level required to halt the COVID-19 epidemics in affected countries

(2020) Kin On Kwok et al.   JOURNAL OF INFECTION

COVID-19 vaccine development pipeline gears up

(2020) Asher Mullard   LANCET

Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

(2020) Noe B. Mercado et al.   NATURE

Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques

(2020) Wei Deng et al.   SCIENCE

COVID-19 Vaccine: A comprehensive status report

(2020) Simran Preet Kaur et al.   VIRUS RESEARCH

The socio-economic implications of the coronavirus pandemic (COVID-19): A review

(2020) Maria Nicola et al.   International Journal of Surgery

SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates

(2020) Gregory A Poland et al.   LANCET

COVID-19: A review of therapeutic strategies and vaccine candidates

(2020) Vladislav Izda et al.   CLINICAL IMMUNOLOGY

Current COVID-19 vaccine candidates: Implications in the Saudi population

(2020) AlAnoud TofailAhmed Raja et al.   SAUDI PHARMACEUTICAL JOURNAL

Dose finding for new vaccines: The role for immunostimulation/immunodynamic modelling

(2019) Sophie J. Rhodes et al.   JOURNAL OF THEORETICAL BIOLOGY

Using vaccine Immunostimulation/Immunodynamic modelling methods to inform vaccine dose decision-making

(2018) Sophie J. Rhodes et al.   npj Vaccines

Multicriteria decision analysis (MCDA) in health care: a systematic review of the main characteristics and methodological steps

(2018) Talita D. C. Frazão et al.   BMC Medical Informatics and Decision Making

A Bayesian design for phase I cancer therapeutic vaccine trials

(2018) Chenguang Wang et al.   STATISTICS IN MEDICINE

Exploring the impact of inoculum dose on host immunity and morbidity to inform model-based vaccine design

(2018) Andreas Handel et al.   PLoS Computational Biology

WHO guide on the economic evaluation of influenza vaccination

(2017) Anthony T. Newall et al.   Influenza and Other Respiratory Viruses

The TB vaccine H56+IC31 dose-response curve is peaked not saturating: Data generation for new mathematical modelling methods to inform vaccine dose decisions

(2016) Sophie J. Rhodes et al.   VACCINE

The contribution of vaccination to global health: past, present and future

(2014) B. Greenwood   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A safety grading scale to support dose escalation and define stopping rules for healthy subject first-entry-into-man studies

(2010) Michel Sibille et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Vaccine presentation in the USA: economics of prefilled syringes versus multidose vials for influenza vaccination

(2010) Claudia C Pereira et al.   Expert Review of Vaccines

Dose Escalation Methods in Phase I Cancer Clinical Trials

(2009) Christophe Le Tourneau et al.   JNCI-Journal of the National Cancer Institute