EGCG Enhanced the Anti-tumor Effect of Doxorubicine in Bladder Cancer via NF-κB/MDM2/p53 Pathway

Combination of 5-Florouracil and polyphenol EGCG exerts suppressive effects on oral cancer cells exposed to radiation

(2019) Eduardo Pons-Fuster López et al.   ARCHIVES OF ORAL BIOLOGY

Enhanced anti-colon cancer efficacy of 5-fluorouracil by epigallocatechin-3- gallate co-loaded in wheat germ agglutinin-conjugated nanoparticles

(2019) Ruoning Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Autophagy and doxorubicin resistance in cancer

(2018) Chao Chen et al.   ANTI-CANCER DRUGS

Regulation of the Mdm2–p53 pathway by the ubiquitin E3 ligase MARCH7

(2018) Kailiang Zhao et al.   EMBO REPORTS

Molecular mechanism of doxorubicin-induced cardiomyopathy – An update

(2018) Kaviyarasi Renu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Green tea extract modulates oxidative tissue injury in beta-thalassemic mice by chelation of redox iron and inhibition of lipid peroxidation

(2018) Pimpisid Koonyosying et al.   BIOMEDICINE & PHARMACOTHERAPY

Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells

(2018) Joshua Heyza et al.   Nutrients

Bladder Cancer Incidence and Mortality: A Global Overview and Recent Trends

(2017) Sebastien Antoni et al.   EUROPEAN UROLOGY

EGCG inhibited bladder cancer SW780 cell proliferation and migration both in vitro and in vivo via down-regulation of NF-κB and MMP-9

(2017) Ke-Wang Luo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

EGCG/gelatin-doxorubicin gold nanoparticles enhance therapeutic efficacy of doxorubicin for prostate cancer treatment

(2016) Li-Chu Tsai et al.   Nanomedicine

Bioactive natural products for chemoprevention and treatment of castration-resistant prostate cancer

(2016) Georgios Kallifatidis et al.   SEMINARS IN CANCER BIOLOGY

Combination of erlotinib and EGCG induces apoptosis of head and neck cancers through posttranscriptional regulation of Bim and Bcl-2

(2015) Abedul Haque et al.   APOPTOSIS

Epigallocatechin-3-gallate pretreatment attenuates doxorubicin-induced cardiotoxicity in rats: A mechanistic study

(2015) Noha M. Saeed et al.   BIOCHEMICAL PHARMACOLOGY

Bim directly antagonizes Bcl-xl in doxorubicin-induced prostate cancer cell apoptosis independently of p53

(2015) Min-Chi Yang et al.   CELL CYCLE

Differential proteomic analysis reveals that EGCG inhibits HDGF and activates apoptosis to increase the sensitivity of non-small cells lung cancer to chemotherapy

(2015) Ali Flores-Pérez et al.   Proteomics Clinical Applications

EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer

(2015) Xuemin Wang et al.   PLoS One

Mitochondrial Modulation by Epigallocatechin 3-Gallate Ameliorates Cisplatin Induced Renal Injury through Decreasing Oxidative/Nitrative Stress, Inflammation and NF-kB in Mice

(2015) Hao Pan et al.   PLoS One

p53-Independent Roles of MDM2 in NF-κB Signaling: Implications for Cancer Therapy, Wound Healing, and Autoimmune Diseases

(2015) Dana Thomasova et al.   NEOPLASIA

Double-Edged Swords as Cancer Therapeutics: Novel, Orally Active, Small Molecules Simultaneously Inhibit p53–MDM2 Interaction and the NF-κB Pathway

(2014) Chunlin Zhuang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Green tea (Camellia sinensis) extract inhibits both the metastasis and osteolytic components of mammary cancer 4T1 lesions in mice

(2014) Ke-Wang Luo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Autophagy Inhibition Contributes to the Synergistic Interaction between EGCG and Doxorubicin to Kill the Hepatoma Hep3B Cells

(2014) Li Chen et al.   PLoS One

The mitochondrial cyclophilin D/p53 complexation mediates doxorubicin-induced non-apoptotic death of A549 lung cancer cells

(2013) Jia-huan Lu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Epigallocatechin gallate promotes p53 accumulation and activity via the inhibition of MDM2-mediated p53 ubiquitination in human lung cancer cells

(2013) LONGYU JIN et al.   ONCOLOGY REPORTS