Article
Chemistry, Multidisciplinary
Lindsay Schneider, Michelle Fraser, Anubhav Tripathi
Summary: By integrating microscale purification and macroscale PCR amplification, we have developed an automated NGS DNA library preparation device that significantly reduces hands-on time and sample processing volume. Tested in the clinically important field of PGT-A, the platform has yielded accurate sequencing results.
Article
Chemistry, Multidisciplinary
Tania Sierra, Ilhoon Jang, Eka Noviana, Agustin G. Crevillen, Alberto Escarpa, Charles S. Henry
Summary: A pump-free microfluidic device for the electrochemical determination of AGP was proposed and demonstrated to be successful. The device allows all analytical steps to be carried out inside, with a wide linear range, low detection limit, and applicability to commercial serum samples.
Article
Electrochemistry
Brenda M. de C. Costa, Sophie Griveau, Fethi Bedioui, Fanny d' Orlye, Jose Alberto F. da Silva, Anne Varenne
Summary: We demonstrate the concept of a reusable 3D printed separation device with integrated electrodes for electrochemical detection. The device was optimized for easy and low-cost fabrication and showed good repeatability and linear response in the tested concentration range.
ELECTROCHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Mario A. Cornejo, Thomas H. Linz
Summary: This report presents a simple and rapid method for directly quantifying multiple miRNAs using microfluidic thermal gel electrophoresis (TGE). The method utilizes fluorescent probes and an innovative microfluidic device to achieve accurate miRNA measurement, and it has been validated with cell extracts. This technique has the potential for automation and can be valuable for clinical and pharmaceutical analyses.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Thaisa Aparecida Baldo, Camila dos Anjos Proenca, Fabiana da Silva Felix, Tayane Aguiar Freitas, Solange Kazumi Sakata, Lucio Angnes, Ronaldo Censi Faria
Summary: The study developed a new detection method using magnetic beads and antibodies to quickly and accurately detect ovalbumin in wine samples. This method was validated on five wine samples and showed excellent accuracy compared to enzyme-linked immunosorbent assay (ELISA).
Article
Chemistry, Multidisciplinary
Vandana Nagal, Marya Khan, Sakeena Masrat, Shamshad Alam, Akil Ahmad, Mohammed B. Alshammari, Kiesar Sideeq Bhat, Rafiq Ahmad
Summary: Enzymeless sensors are stable, fast, and reliable devices for biomolecule detection and disease diagnosis. In this study, hexagonal cobalt oxide nanosheets were synthesized using a hydrothermal method, and then utilized to fabricate an ultra-sensitive enzymeless electrochemical-based uric acid (UA) sensor. The cobalt oxide nanosheet-based UA sensor showed a good response for UA detection, with ultra-sensitivity and a low limit of detection. The developed sensor demonstrated good stability, reproducibility, and specificity for UA.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Analytical
Sonal Fande, Khairunnisa Amreen, D. Sriram, Sanket Goel
Summary: A microfluidic-based electrochemical device was developed for fast and sensitive detection of Escherichia coli. The device enables incubator-free bacterial culturing in ambient atmosphere and simultaneous monitoring and detection of bacterial growth using electrochemical methods. The device showed high sensitivity and quantification limit, and was successfully used to monitor bacterial growth in real samples.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Chonghui Yang, Yujing Yang, Gaozhen Zhao, Huan Wang, Yang Dai, Xiaowen Huang
Summary: The sensitive and rapid detection of microsamples is crucial for early diagnosis of diseases. We developed a low-cost smartphone-based fluorescence detection device (Smartphone-BFDD) without precision equipment for rapid identification and quantification of biomarkers on glass capillary. The device combines microfluidic technology with RGB image analysis, effectively reducing the sample volume to 20 μL and detection time to only 30 min. This device provides potential applications for different biomarkers and offers wide use for rapid biochemical analysis in biomedical research.
Article
Chemistry, Analytical
Audrius Maruska, Tomas Drevinskas, Mantas Stankevicius, Kristina Bimbiraite-Surviliene, Vilma Kaskoniene, Linas Jonusauskas, Roaldas Gadonas, Staffan Nilsson, Olga Kornysova
Summary: This work describes the design and characterization of a multi-cell capacitively coupled contactless conductivity detection system, capable of simultaneously acquiring data from multiple detector cells and easily upgradable to 64 detection cells. The system demonstrated sensitivity to low concentrations of various solutions in water and the ability to distinguish different mixtures of organic solvents. It is expected to be used in conjunction with multi-channel separation devices for monitoring simultaneous processes.
ANALYTICAL METHODS
(2021)
Article
Chemistry, Analytical
Wanxin Li, Jiaxin Sun, Yao Xin, Yu Han, Yanyang Sun, Aijun Li, Zhi Wang
Summary: A novel nanozyme was synthesized for the detection of resveratrol. This nanozyme exhibited excellent peroxidase-like activity and the colorimetric reaction could be completed within 20 minutes.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Multidisciplinary
Velu Duraisamy, Velayutham Sudha, Kuppusamy Annadurai, Sakkarapalayam Murugesan Senthil Kumar, Rangasamy Thangamuthu
Summary: The development of active and defective sites in mesoporous carbon materials is crucial for high-performance sensors. NHCS-1000, with improved surface area, porosity, and N-doping, showed enhanced electrocatalytic activity and was successfully utilized for the simultaneous detection of multiple analytes.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Analytical
Xiaoxing Weng, Chen Li, Changqing Chen, Gang Wang, Chenghao Xia, Lianyou Zheng
Summary: This paper focuses on the rapid detection of pathogenic microorganisms, using tobacco ringspot virus as the target. It designs an impedance detection and analysis platform based on microfluidic impedance method, establishes an equivalent circuit model for analyzing experimental results, and determines the optimal detection frequency for tobacco ringspot virus. An impedance-concentration regression model is established for detecting tobacco ringspot virus in a detection device. The designed device, using an AD5933 impedance detection chip, is comprehensively tested and verifies its feasibility, providing technical support for on-site detection of pathogenic microorganisms.
Article
Chemistry, Analytical
Ilhoon Jang, Hyunwoong Kang, Simon Song, David S. Dandy, Brian J. Geiss, Charles S. Henry
Summary: Capillary-driven microfluidic devices made from paper and polyester film are commonly used due to their low cost and lack of external pumps. However, controlling flow in these devices can be challenging due to the sole reliance on capillary forces. This study introduces new flow control methods, such as push and burst valve systems, for increased functionality in laminate capillary-driven microfluidic devices. These methods enable precise control of flow direction, concentration, and velocity, ultimately offering new design possibilities for on-site analysis in various fields.
Article
Chemistry, Analytical
Hongyu Nie, Zhihui Li, Xiaokun Wang, Rongmeng Gu, Hongyan Yuan, Yong Guo, Dan Xiao
Summary: In this study, a multi-input capacitively coupled contactless conductivity detector (MICD)-D-4 was proposed with high sensitivity, and further improved by combining it with differential detection to form (DFMICD)-D-4. The new detector showed improved performance compared to traditional single-input and double-input detectors, with a higher response-to-baseline ratio and a low limit of detection (0.7 nM). It can be applied to the detection of low-conductivity solutions and total dissolved solids (TDS) analysis, demonstrating its versatility and superiority over standard conductivity meters.
Review
Chemistry, Analytical
Didem Nur Unal, Sercan Yildirim, Sevinc Kurbanoglu, Bengi Uslu
Summary: Surfactants are frequently used in different fields of analytical chemistry to reduce the interfacial tension of immiscible liquids by forming micelles through hydrophobic and hydrophilic groups. Their use in techniques such as chromatography and electrochemistry has been noted for improving separation efficiency and increasing sensor selectivity and sensitivity.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Marne Carvalho de Vasconcellos, Cicero de Oliveira Costa, Emanuella Gomes da Silva Terto, Maria Aline F. B. de Moura, Camila Calado de Vasconcelos, Fabiane Caxico de Abreu, Telma Leda Gomes de Lemos, Leticia Veras Costa-Lotufo, Raquel Carvalho Montenegro, Marilia Oliveira Fonseca Goulart
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2016)
Article
Electrochemistry
Caio Cesar de Lima Franca, Emanuella G. da Silva Terto, Marcos V. Dias-Vermelho, Anielle Christine A. Silva, Noelio O. Dantas, Fabiane Caxico de Abreu
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
(2016)
Article
Chemistry, Analytical
Andrea Claudia Oliveira Silva, Luis Carlos Ferreira de Oliveira, Angladis Vieira Delfino, Mario Roberto Meneghetti, Fabiane Caxico de Abreu
JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY
(2016)
Article
Materials Science, Multidisciplinary
Cassia Roberta Pontes Silva, Fabricia da Rocha Ferreira, Geovana Dresch Webler, Antonio Osimar Sousa da Silva, Fabiane Caxico de Abreu, Eduardo J. S. Fonseca
MATERIALS RESEARCH EXPRESS
(2017)
Article
Biochemistry & Molecular Biology
Francisco W. A. Barros, Teresinha Goncalves Silva, Marina Galdino da Rocha Pitta, Daniel P. Bezerra, Leticia V. Costa-Lotufo, Manoel Odorico de Moraes, Claudia Pessoa, Maria Aline F. B. de Moura, Fabiane C. de Abreu, Maria do Carmo Alves de Lima, Suely Lins Galdino, Ivan da Rocha Pitta, Marilia O. F. Goulart
BIOORGANIC & MEDICINAL CHEMISTRY
(2012)
Article
Chemistry, Medicinal
Alane Cabral de Oliveira, Emanuella Gomes da Silva, Danilo Damasceno Rocha, Elizabeth A. Hillard, Pascal Pigeon, Gerard Jaouen, Felipe A. R. Rodrigues, Fabiane C. de Abreu, Fabricia da Rocha Ferreira, Marilia O. F. Goulart, Leticia V. Costa-Lotufo
Article
Electrochemistry
Jonathan E. Halls, Amal A. Altalhi, Fabiane C. de Abreu, Marilia O. F. Goulart, Jay D. Wadhawan
ELECTROCHEMISTRY COMMUNICATIONS
(2012)
Article
Biochemical Research Methods
Diogenes Meneses, Dulan B. Gunasekara, Pann Pichetsurnthorn, Jose A. F. da Silva, Fabiane C. de Abreu, Susan M. Lunte
Article
Thermodynamics
Paulo R. B. de Miranda, Tarsila S. Silva, Fabiane Caxico de Abreu, Iara B. Valentim, Marilia. O. F. Goulart
JOURNAL OF CHEMICAL AND ENGINEERING DATA
(2014)
Article
Toxicology
A. J. Araujo, A. A. de Souza, E. N. da Silva Junior, J. D. B. Marinho-Filho, M. A. B. F. de Moura, D. D. Rocha, M. C. Vasconcellos, C. O. Costa, C. Pessoa, M. O. de Moraes, V. F. Ferreira, F. C. de Abreu, A. V. Pinto, R. C. Montenegro, L. V. Costa-Lotufo, M. O. F. Goulart
TOXICOLOGY IN VITRO
(2012)
Article
Biophysics
Katherine Lozano Untiveros, Emanuella Gomes da Silva, Fabiane Caxico de Abreu, Edeildo Ferreira da Silva-Junior, Joao Xavier de Araujo-Junior, Thiago Mendoca de Aquino, Stephanie M. Armas, Ricardo Olimpio de Moura, Francisco J. B. Mendonca-Junior, Vanessa Lima Serafim, Karin Chumbimuni-Torres
BIOSENSORS & BIOELECTRONICS
(2019)
Article
Chemistry, Physical
Sandra Rodrigues da Silva, Nilson J. A. de Albuquerque, Rusiene M. de Almeida, Fabiane C. de Abreu
Article
Chemistry, Multidisciplinary
Cicero de O. Costa, Erivaldo de O. Costa, Fabricia da R. Ferreira, Luciana da S. Viana, Leonardo V. da Silva, Francisco de A. dos Santos Silva, Fabiane C. de Abreu, Isis M. Figueiredo, Waldomiro Pinho, Edson de S. Bento, Telma L. G. Lemos, Otilia D. L. Pessoa, Benjamin Aguilera-Venegas, Ester Norambuena, Claudio Olea-Azar, Marilia O. F. Goulart
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2012)
Article
Chemistry, Multidisciplinary
Yen G. de Paiva, Antonio A. de Souza, Claudio G. Lima-Junior, Fabio P. L. Silva, Edilson B. A. Filho, Camila C. de Vasconcelos, Fabiane C. de Abreu, Marilia O. F. Goulart, Mario L. A. A. Vasconcellos
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2012)