Valeric Acid Suppresses Liver Cancer Development by Acting as a Novel HDAC Inhibitor

Iridoids from Valeriana jatamansi induce autophagy-associated cell death via the PDK1/Akt/mTOR pathway in HCT116 human colorectal carcinoma cells

(2019) Yu-Zhu Tan et al.   BIOORGANIC CHEMISTRY

Mortality, morbidity, and risk factors in China and its provinces, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2019) Maigeng Zhou et al.   LANCET

Current status of nanomaterial-based treatment for hepatocellular carcinoma

(2019) Badriya Baig et al.   BIOMEDICINE & PHARMACOTHERAPY

Histone deacetylase 3 promotes liver regeneration and liver cancer cells proliferation through signal transducer and activator of transcription 3 signaling pathway

(2018) Xu-Feng Lu et al.   Cell Death & Disease

Combination Therapy With Histone Deacetylase Inhibitors (HDACi) for the Treatment of Cancer: Achieving the Full Therapeutic Potential of HDACi

(2018) Amila Suraweera et al.   Frontiers in Oncology

The Therapeutic Strategy of HDAC6 Inhibitors in Lymphoproliferative Disease

(2018) Maria Cosenza et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells

(2018) Ala’a Al-Hrout et al.   Scientific Reports

HDAC inhibitor PAC-320 induces G2/M cell cycle arrest and apoptosis in human prostate cancer

(2017) Zhixiong Dong et al.   Oncotarget

Development of a therapeutic model of precancerous liver using crocin-coated magnetite nanoparticles

(2016) Rkia El-Kharrag et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Valerenic acid and Valeriana officinalis extracts delay onset of Pentylenetetrazole (PTZ)-Induced seizures in adult Danio rerio (Zebrafish)

(2015) Bianca A. Torres-Hernández et al.   BMC Complementary and Alternative Medicine

Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds

(2015) A.R.M. Ruhul Amin et al.   SEMINARS IN CANCER BIOLOGY

Sustained proliferation in cancer: Mechanisms and novel therapeutic targets

(2015) Mark A. Feitelson et al.   SEMINARS IN CANCER BIOLOGY

Histone deacetylase inhibitors and cell death

(2014) Jing Zhang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Valerian Inhibits Rat Hepatocarcinogenesis by Activating GABA(A) Receptor-Mediated Signaling

(2014) Anna Kakehashi et al.   PLoS One

Erasers of Histone Acetylation: The Histone Deacetylase Enzymes

(2014) E. Seto et al.   Cold Spring Harbor Perspectives in Biology

Shaping the interaction landscape of bioactive molecules

(2013) David Gfeller et al.   BIOINFORMATICS

Differential expression of histone deacetylases HDAC1, 2 and 3 in human breast cancer - overexpression of HDAC2 and HDAC3 is associated with clinicopathological indicators of disease progression

(2013) Berit Maria Müller et al.   BMC CANCER

Valeriana jatamansi Constituent IVHD-valtrate As a Novel Therapeutic Agent to Human Ovarian Cancer: in vitro and in vivo Activities and Mechanisms

(2013) Xiaoguang Li et al.   CURRENT CANCER DRUG TARGETS

Cationic lipid nanoparticles for therapeutic delivery of siRNA and miRNA to murine liver tumor

(2013) Shu-hao Hsu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Hep G2 is a hepatoblastoma-derived cell line

(2009) Dolores López-Terrada et al.   HUMAN PATHOLOGY

The size of endothelial fenestrae in human liver sinusoids: implications for hepatocyte-directed gene transfer

(2008) E Wisse et al.   GENE THERAPY