HDAC inhibition prevents transgene expression downregulation and loss of function in T cell receptor-transduced T cells

Published 2021 View Full Article

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Title
HDAC inhibition prevents transgene expression downregulation and loss of function in T cell receptor-transduced T cells
Authors
Keywords
TCR-transduced T cells, gene-modified T cells, HDAC inhibitors, sodium butyrate, vorinostat, gene silencing, transgene silencing, cancer immunotherapy, cell therapy, functional responses
Journal
Molecular Therapy-Oncolytics
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-01-26
DOI
10.1016/j.omto.2021.01.014

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