Article
Ophthalmology
Lisa A. Jones-Jordan, Loraine T. Sinnott, Raymond H. Chu, Susan A. Cotter, Robert N. Kleinstein, Ruth E. Manny, Donald O. Mutti, J. Daniel Twelker, Karla Zadnik
Summary: The study found that younger age, female sex, and race/ethnicity were factors associated with faster myopic progression. This multivariate model can inform the prediction of myopia progression rates for clinical trial planning.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Medicine, General & Internal
Hanyu Zhang, Carly S. Y. Lam, Wing-Chun Tang, Myra Leung, Hua Qi, Paul H. Lee, Chi-Ho To
Summary: The aim of this study is to investigate the influence of baseline relative peripheral refraction (RPR) on myopia control effects in Chinese myopic children wearing Defocus Incorporated Multiple Segments (DIMS) lenses. The results showed that baseline myopic RPR was associated with more myopic progression and greater axial elongation in the DIMS group, but not in the single vision (SV) group. Children with baseline myopic RPR in the DIMS group had statistically significant more myopia progression and axial elongation compared to those with baseline hyperopic RPR.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Dandan Ma, Shifei Wei, Shi-Ming Li, Xiaohui Yang, Kai Cao, Jianping Hu, Xiaoxia Peng, Ruohua Yan, Jing Fu, Andrzej Grzybowski, Zi-Bing Jin, Ningli Wang
Summary: During the COVID-19 pandemic, study-at-home accelerated the change of refraction toward myopia in children.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Ophthalmology
Yajing Yang, Sin Wan Cheung, Pauline Cho, Stephen J. Vincent
Summary: The study found that the estimated myopia progression by the BHVI Myopia Calculator was in close agreement with the actual measured values after 1 and 2 years, but caution is advised when interpreting the data as it only fell within the 95% confidence interval for a relatively small percentage of children.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Public, Environmental & Occupational Health
Wujiao Wang, Lu Zhu, Shijie Zheng, Yan Ji, Yongguo Xiang, Bingjing Lv, Liang Xiong, Zhuoyu Li, Shenglan Yi, Hongyun Huang, Li Zhang, Fangli Liu, Wenjuan Wan, Ke Hu
Summary: This study found that the prevalence of myopia among children and adolescents in Chongqing increased significantly during the COVID-19 pandemic, which was related to excessive use of digital devices. It is recommended to provide suitable digital devices for online classes and encourage outdoor activities to prevent myopia.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Ophthalmology
Jost B. Jonas, Marcus Ang, Pauline Cho, Jeremy A. Guggenheim, Ming Guang He, Monica Jong, Nicola S. Logan, Maria Liu, Ian Morgan, Kyoko Ohno-Matsui, Olavi Parssinen, Serge Resnikoff, Padmaja Sankaridurg, Seang-Mei Saw, Earl L. Smith, Donald T. H. Tan, Jeffrey J. Walline, Christine F. Wildsoet, Pei-Chang Wu, Xiaoying Zhu, James S. Wolffsohn
Summary: The prevalence of myopia is increasing in East and Southeast Asia, with strategies needed to reduce its progression. Encouraging outdoor activities and using low-dose atropine eye drops are beneficial measures for reducing myopia development. Individual risk-to-benefit ratios need to be considered for different treatment options based on age, health, and lifestyle.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Multidisciplinary Sciences
Hae Ri Yum, Shin Hae Park, Sun Young Shin
Summary: The study found that during the COVID-19 pandemic, children treated with low-concentration atropine experienced a significant increase in myopic progression, especially in children aged 5 to 10. Compared to pre-pandemic levels, children spent significantly more time using computers and smartphones and significantly less time engaging in outdoor activities during the pandemic.
Article
Ophthalmology
Ian Flitcroft, John Ainsworth, Audrey Chia, Susan Cotter, Elise Harb, Zi-Bing Jin, Caroline C. W. Klaver, Anthony T. Moore, Ken K. Nischal, Kyoko Ohno-Matsui, Evelyn A. Paysse, Michael X. Repka, Irina Y. Smirnova, Martin Snead, Virginie J. M. Verhoeven, Pavan K. Verkicharla
Summary: The purpose of this study was to evaluate the epidemiology, etiology, clinical assessment, investigation, management, and visual consequences of high myopia in infants and young children. The findings suggest that high myopia is rare in pre-school children, with a prevalence less than 1%. The etiology of myopia in these children differs from older children, with a high rate of secondary myopia associated with prematurity or genetic causes. The clinical management of high myopia in infants and young children is complex and often requires a multidisciplinary approach, including investigation, optical correction, and myopia control treatments.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Medicine, General & Internal
Tomoki Maruyama, Erisa Yotsukura, Hidemasa Torii, Kiwako Mori, Mikako Inokuchi, Mitsuaki Tokumura, Debabrata Hazra, Mamoru Ogawa, Akiko Hanyuda, Kazuo Tsubota, Toshihide Kurihara, Kazuno Negishi
Summary: The prevalence of myopia is high among Japanese schoolchildren, with almost half of preschoolers being myopic. The time spent using digital devices is positively associated with lens thickness, while reading time is negatively associated with lens thickness, spherical equivalent, axial length, and vitreous chamber depth.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
Luyao Ye, Hannan Xu, Ya Shi, Yao Yin, Tao Yu, Yajun Peng, Shanshan Li, Jiangnan He, Jianfeng Zhu, Xun Xu
Summary: This study investigated the efficacy and safety of consecutive use of 1% and 0.01% atropine compared with 0.01% atropine alone in the treatment of myopia. The results showed that consecutive use of atropine had a better effect in slowing myopia progression than using atropine alone.
OPHTHALMOLOGY AND THERAPY
(2022)
Article
Ophthalmology
Fei Luo, Jie Hao, Lei Li, Jiawen Liu, Weiwei Chen, Jing Fu, Nathan Congdon
Summary: The purpose of this study was to investigate the association between refractive error, habitual accommodative tone (HAT) and the incidence and progression of myopia in Tibetan children. The results showed that baseline spherical equivalent (SE) was significantly associated with the occurrence of myopia and its progression. Additionally, lower baseline HAT was found to be potentially associated with myopic development in hyperopic children.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Review
Pharmacology & Pharmacy
Alberto Chierigo, Lorenzo Ferro Desideri, Carlo Enrico Traverso, Aldo Vagge
Summary: Several approaches have been investigated to prevent myopia progression in children and teenagers, among them, topical atropine has shown promising results. However, the optimal formulation and treatment algorithm have yet to be determined. Further larger-scale studies are needed to characterize the clinical efficacy of atropine and define the optimal dosage and treatment regimen.
Article
Ophthalmology
Mark A. Bullimore, Samantha Sze -Yee Lee, Katrina L. Schmid, Jos J. Rozema, Nicolas Leveziel, Edward A. H. Mallen, Nina Jacobsen, Rafael Iribarren, Pavan K. Verkicharla, Jan Roelof Polling, Paul Chamberlain
Summary: Myopia can start and progress during childhood as well as during adulthood. This review aims to summarize the published data on myopia onset and progression in young adults aged 18 to 40, to characterize myopia in this age group, and to identify gaps in the current understanding.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Public, Environmental & Occupational Health
Wenjing Wang, Shuzhen Peng, Faxue Zhang, Boya Zhu, Longjiang Zhang, Xiaodong Tan
Summary: This study investigated the changes in vision among children before and after the COVID-19 pandemic. It found an increase in myopia prevalence among younger children, but slight improvement in vision in 2021. These results suggest the need to focus on vision prevention and control in preschool-aged children even after the pandemic.
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
(2022)
Article
Medicine, Research & Experimental
Osamu Hieda, Yo Nakamura, Takahiro Hiraoka, Miho Kojima, Tetsuro Oshika, Chie Sotozono
Summary: This study aims to investigate the efficacy of peripheral low add multifocal soft contact lenses for suppressing the progression of myopia in myopic elementary school children. A total of 100 myopic school children will be included in the prospective randomized controlled trial, with the primary outcome being the change in axial length over a 2-year period.
Article
Ophthalmology
Mijie Li, Carla Lanca, Chuen-Seng Tan, Li-Lian Foo, Chen-Hsin Sun, Fabian Yap, Raymond P. Najjar, Charumathi Sabanayagam, Seang-Mei Saw
Summary: This study evaluated the association between reported time outdoors and light exposure patterns with myopia in 9-year-old Singaporean children. The findings showed that greater reported time outdoors was associated with a lower risk of myopia, while light levels and specific light measures did not have an impact.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Li Lian Foo, Lingqian Xu, Charumathi Sabanayagam, Hla M. Htoon, Han Nian Marcus Ang, Jingwen Zhang, Kyoko Ohno-Matsui, Ching Yu Cheng, Quan Hoang, Chuen-Seng Tan, Seang-Mei Saw, Chee Wai Wong
Summary: The purpose of this study was to investigate the predictive factors for myopic macular degeneration (MMD) and progression in adults with myopia. The study found that in adults without MMD, tessellated fundus, age, spherical equivalent (SE), and axial length (AL) were good predictors for incident MMD. In adults with MMD, older age, more severe myopia, and longer AL were independent risk factors for progression.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Letter
Ophthalmology
Carla Lanca, Olavi Parssinen, Shiva Mehravaran, Klaus Nordhausen, Mohammad Hassan Emamian, Andrzej Grzybowski
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Carla Lanca, Mohammad Hassan Emamian, Yee Ling Wong, Hassan Hashemi, Mehdi Khabazkhoob, Andrzej Grzybowski, Seang Mei Saw, Akbar Fotouhi
Summary: This study aimed to determine the spherical equivalent (SE) progression among children in the Shahroud School Children Eye Cohort Study in Iran. The results showed that older age, female sex, near work, parental myopia, and greater myopic baseline SE were associated with myopic shift.
Article
Public, Environmental & Occupational Health
Gregory Ang, Sarah Martine Edney, Chuen Seng Tan, Nicole Lim, Jeremy Tan, Falk Mueller-Riemenschneider, Cynthia Chen
Summary: Physical inactivity is a global health challenge, and a population-wide mobile health intervention in Singapore (NSC3) was found to be effective in increasing participants' daily step counts. Two booster challenges, Personal Pledge and Corporate Challenge, were associated with additional increases in step counts.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Medicine, General & Internal
Shilpa Tyagi, Nan Luo, Chuen Seng Tan, Kelvin Bryan Tan, Boon Yeow Tan, Edward Menon, N. Venketasubramanian, Wei Chin Loh, Shu Hui Fan, Kenneth Lam Thuan Yang, Audrey Swee Ling Chan, Aysha Farwin, Zunairah Binti Lukman, Gerald Choon-Huat Koh
Summary: This study aimed to explore the caregiving experience of stroke survivors and their family caregivers across different caregiver identities. The findings highlighted the heterogeneity in factors affecting caregiving experience across spouse and adult-child caregivers. Practical implications include conducting a needs assessment for caregiver-stroke survivor dyads and providing tailored support, training and information to help caregivers cope better.
Article
Public, Environmental & Occupational Health
Alexander Wilhelm Gorny, Jonathan Yap, Jia Wei Neo, Wei En Chow, Khung Keong Yeo, Chuen Seng Tan, Falk Mueller-Riemenschneider
Summary: This study investigated the association between cardiorespiratory fitness, body mass index (BMI), incidence of major acute cardiovascular events (MACE), and all-cause mortality (ACM). The study included 212,631 healthy young men aged 16 to 25 years who had undergone medical examination and fitness testing. Lower cardiorespiratory fitness and higher BMI were associated with increased hazards of MACE and ACM.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Ophthalmology
Alejandra Iurescia, Rafael Iribarren, Carla Lanca, Andrzej Grzybowski
Summary: NSAVA was found to be a common cause of vision problems in children attending a paediatric ophthalmology clinic. Children who self-reported reading problems were more likely to have accommodative infacility.
ACTA OPHTHALMOLOGICA
(2023)
Article
Ophthalmology
Li Lian Foo, Chuen-Seng Tan, Brennan Noel, Hla M. Htoon, Raymond P. Najjar, Biten Kathrani, Charumathi Sabanayagam, Seang-Mei Saw
Summary: The purpose of this study was to evaluate factors influencing myopia stabilisation in Singapore. The longitudinal natural history of 424 myopic participants from 1999 to 2022 was evaluated, and it was found that 82.3% of people had stabilisation of myopia within 10 years. The study also found that males and non-Chinese ethnicities were more likely to achieve myopia stabilisation.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Biology
Charumathi Sabanayagam, Feng He, Simon Nusinovici, Jialiang Li, Cynthia Lim, Gavin Tan, Ching Yu Cheng
Summary: This study compares the accuracy of different machine learning algorithms in predicting diabetic kidney disease. The results show that machine learning models outperform logistic regression and identify novel risk factors.
Article
Public, Environmental & Occupational Health
Lixia Ge, Saima Hilal, Falk Mueller-Riemenschneider, Chuen Seng Tan
Summary: This study examines the association between different domain-specific physical activities and cardiometabolic factors using longitudinal data. The findings suggest that different domains of physical activity have differential associations with individual cardiometabolic risk factors. Further research is needed to confirm these findings.
JOURNAL OF PHYSICAL ACTIVITY & HEALTH
(2023)
Article
Ophthalmology
Hassan Hashemi, Mehdi Khabazkhoob, Elham Azizi, Rafael Iribarren, Carla Lanca, Andrzej Grzybowski, Jos J. Rozema, Mohammad Hassan Emamian, Akbar Fotouhi
Summary: The study found that the crystalline lens power decreases and thickness slightly increases in 6 to 12-year-old children over a three-year period. These changes are associated with refractive errors, place of residence, age, gender, and outdoor activity time.