Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways

Genistein suppresses psoriasis-related inflammation through a STAT3–NF-κB-dependent mechanism in keratinocytes

(2019) Ailin Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Catalpol Alleviates Adriamycin‐Induced Nephropathy by Activating the SIRT1 Signalling Pathway In Vivo and In Vitro

(2019) Jiangnan Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Catalpol ameliorates LPS-induced endometritis by inhibiting inflammation and TLR4/NF-κB signaling

(2019) Hua Zhang et al.   Journal of Zhejiang University-SCIENCE B

SIRT1 protects against urban particulate matter-induced airway inflammation

(2019) Tianwen Lai et al.   International Journal of Chronic Obstructive Pulmonary Disease

SIRT1 Controls Acetaminophen Hepatotoxicity by Modulating Inflammation and Oxidative Stress

(2018) Patricia Rada et al.   ANTIOXIDANTS & REDOX SIGNALING

Catalpol inhibits migration and induces apoptosis in gastric cancer cells and in athymic nude mice

(2018) Zheng-Hua Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis

(2018) Zhaoguo Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Rapamycin ameliorates psoriasis by regulating the expression and methylation levels of Tropomyosin via ERK1/2 and mTOR pathways in vitro and in vivo

(2018) Minhong Gao et al.   EXPERIMENTAL DERMATOLOGY

Murine models of psoriasis and their usefulness for drug discovery

(2018) Shih-Yi Chuang et al.   Expert Opinion on Drug Discovery

A cohort study on the risk of lymphoma and skin cancer in users of topical tacrolimus, pimecrolimus, and corticosteroids (Joint European Longitudinal Lymphoma and Skin Cancer Evaluation – JOELLE study)

(2018) Jordi Castellsague et al.   Clinical Epidemiology

Psoriasis: Keratinocytes or Immune Cells – Which Is the Trigger?

(2018) Farida Benhadou et al.   DERMATOLOGY

Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells

(2018) Huimin Hu et al.   INFLAMMATION

ERK inhibitor JSI287 alleviates imiquimod-induced mice skin lesions by ERK/IL-17 signaling pathway

(2018) Xiaoling Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chemerin/ChemR23 axis triggers an inflammatory response in keratinocytes through ROS-sirt1-NF-κB signaling

(2018) Yuan Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Quercetin ameliorates imiquimod-induced psoriasis-like skin inflammation in mice via the NF-κB pathway

(2017) Haiming Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Catalpol alleviates ovalbumin-induced asthma in mice: Reduced eosinophil infiltration in the lung

(2017) Yanyan Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

CQMUH-011, a novel adamantane sulfonamide compound, inhibits lipopolysaccharide- and D-galactosamine-induced fulminant hepatic failure in mice

(2017) Liping Yan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Paeoniflorin suppressed IL-22 via p38 MAPK pathway and exerts anti-psoriatic effect

(2017) Jinghong Yu et al.   LIFE SCIENCES

Activation of sirtuin 1 by catalpol-induced down-regulation of microRNA-132 attenuates endoplasmic reticulum stress in colitis

(2017) Yongjian Xiong et al.   PHARMACOLOGICAL RESEARCH

Epidermal SIRT1 regulates inflammation, cell migration, and wound healing

(2017) Lei Qiang et al.   Scientific Reports

Catalpol restores LPS-elicited rat microcirculation disorder by regulation of a network of signaling involving inhibition of TLR-4 and SRC

(2016) Yun-Pei Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Evaluation of anti-proliferative and anti-inflammatory activities of Pelagia noctiluca venom in Lipopolysaccharide/Interferon-γ stimulated RAW264.7 macrophages

(2016) Yosra Ayed et al.   BIOMEDICINE & PHARMACOTHERAPY

Terminalia Chebulanin Attenuates Psoriatic Skin Lesion via Regulation of Heme Oxygenase-1

(2016) Jingang An et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Catalpol Protects Pre-Myelinating Oligodendrocytes against Ischemia-induced Oxidative Injury through ERK1/2 Signaling Pathway

(2016) Qiyan Cai et al.   International Journal of Biological Sciences

Anti-diabetic activities of catalpol in db/db mice

(2016) Qinwen Bao et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Antidiabetic and antioxidant effects of catalpol extracted from Rehmannia glutinosa (Di Huang) on rat diabetes induced by streptozotocin and high-fat, high-sugar feed

(2016) Huifeng Zhu et al.   Chinese Medicine

Catalpol ameliorates high-fat diet-induced insulin resistance and adipose tissue inflammation by suppressing the JNK and NF-κB pathways

(2015) Jun Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glycyrrhizin Ameliorates Imiquimod-Induced Psoriasis-like Skin Lesions in BALB/c Mice and Inhibits TNF-a-Induced ICAM-1 Expression via NF-κB/MAPK in HaCaT Cells

(2015) Hui Xiong et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Deficiency of both L-selectin and ICAM-1 exacerbates imiquimod-induced psoriasis-like skin inflammation through increased infiltration of antigen presenting cells

(2015) Aya Mitsui et al.   CLINICAL IMMUNOLOGY

A Randomized, Placebo-Controlled Study of SRT2104, a SIRT1 Activator, in Patients with Moderate to Severe Psoriasis

(2015) James G. Krueger et al.   PLoS One

Hypoglycemic effect of catalpol on high-fat diet/streptozotocin-induced diabetic mice by increasing skeletal muscle mitochondrial biogenesis

(2014) X. Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Catalpol Inhibited the Proliferation of T24 Human Bladder Cancer Cells by Inducing Apoptosis Through the Blockade of Akt-Mediated Anti-apoptotic Signaling

(2014) Di Jin et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Inhibition of TYK2 and JAK1 Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis by Inhibiting IL-22 and the IL-23/IL-17 Axis

(2014) Melissa G. Works et al.   JOURNAL OF IMMUNOLOGY

TLRs to cytokines: Mechanistic insights from the imiquimod mouse model of psoriasis

(2013) Barry Flutter et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Redox regulation of SIRT1 in inflammation and cellular senescence

(2013) Jae-woong Hwang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Curcumin Inhibits Imiquimod-Induced Psoriasis-Like Inflammation by Inhibiting IL-1beta and IL-6 Production in Mice

(2013) Jun Sun et al.   PLoS One

c-Jun N-terminal kinase (JNK)-phospho-c-JUN (ser63/73) pathway is essential for FOXP3 nuclear translocation in psoriasis

(2012) Ling Chen et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

NF-κB: An essential transcription factor in psoriasis

(2012) A.M. Goldminz et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Pathological crosstalk in vitro between T lymphocytes and lesional keratinocytes in psoriasis: necessity of direct cell-to-cell contact

(2012) Guillaume Martin et al.   LABORATORY INVESTIGATION

Casuarinin suppresses TNF-α-induced ICAM-1 expression via blockade of NF-κB activation in HaCaT cells

(2011) Dong-Joo Kwon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting NF- B with a Natural Triterpenoid Alleviates Skin Inflammation in a Mouse Model of Psoriasis

(2009) H. Wang et al.   JOURNAL OF IMMUNOLOGY

Protective effects of catalpol against H2O2-induced oxidative stress in astrocytes primary cultures

(2008) Jing Bi et al.   NEUROSCIENCE LETTERS