miR-146b-5p Enhances the Sensitivity of NSCLC to EGFR Tyrosine Kinase Inhibitors by Regulating the IRAK1/NF-κB Pathway

Extracellular vesicles containing miR-146a attenuate experimental colitis by targeting TRAF6 and IRAK1

(2019) Hui Wu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Strategies to overcome acquired resistance to EGFR TKI in the treatment of non-small cell lung cancer

(2019) J. Gao et al.   Clinical & Translational Oncology

Acquired resistance to EGFR tyrosine kinase inhibitors is mediated by the reactivation of STC2/JUN/AXL signaling in lung cancer

(2019) Yi‐Nan Liu et al.   INTERNATIONAL JOURNAL OF CANCER

SNHG14 confers gefitinib resistance in non-small cell lung cancer by up-regulating ABCB1 via sponging miR-206-3p

(2019) Kai Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

Mechanisms of acquired resistance to first- and second-generation EGFR tyrosine kinase inhibitors

(2018) D Westover et al.   ANNALS OF ONCOLOGY

Osimertinib As First-Line Treatment of EGFR Mutation–Positive Advanced Non–Small-Cell Lung Cancer

(2018) Suresh S. Ramalingam et al.   JOURNAL OF CLINICAL ONCOLOGY

Management of acquired resistance to EGFR TKI–targeted therapy in advanced non-small cell lung cancer

(2018) Shang-Gin Wu et al.   Molecular Cancer

Epigenetic silencing of miR-483-3p promotes acquired gefitinib resistance and EMT in EGFR-mutant NSCLC by targeting integrin β3

(2018) Jinnan Yue et al.   ONCOGENE

NF-κB activation is an early event of changes in gene regulation for acquiring drug resistance in human adenocarcinoma PC-9 cells

(2018) Masashi Fukuoka et al.   PLoS One

Notch3-dependent β-catenin signaling mediates EGFR TKI drug persistence in EGFR mutant NSCLC

(2018) Rajeswara Rao Arasada et al.   Nature Communications

MicroRNA-146b-5p as an oncomiR promotes papillary thyroid carcinoma development by targeting CCDC6

(2018) Meng Jia et al.   CANCER LETTERS

Lung cancer epigenetics: From knowledge to applications

(2017) Michaël Duruisseaux et al.   SEMINARS IN CANCER BIOLOGY

Down-regulation of miR-146b-5p by long noncoding RNA MALAT1 in hepatocellular carcinoma promotes cancer growth and metastasis

(2017) Chao Li et al.   Oncotarget

MiR-146b-5p functions as a suppressor miRNA and prognosis predictor in non-small cell lung cancer

(2017) Yongwen Li et al.   Journal of Cancer

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Inhibition of Casein Kinase 1 Alpha Prevents Acquired Drug Resistance to Erlotinib in EGFR-Mutant Non-Small Cell Lung Cancer

(2015) A. B. Lantermann et al.   CANCER RESEARCH

MiR-146b-5p Promotes Metastasis and Induces Epithelial-Mesenchymal Transition in Thyroid Cancer by Targeting ZNRF3

(2015) Xianzhao Deng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

AKT inactivation causes persistent drug tolerance to EGFR inhibitors

(2015) Osamu Tetsu et al.   PHARMACOLOGICAL RESEARCH

EGFR and NF-κB: partners in cancer

(2015) Kateryna Shostak et al.   TRENDS IN MOLECULAR MEDICINE

miR-96 induces cisplatin chemoresistance in non-small cell lung cancer cells by downregulating SAMD9

(2015) LIN WU et al.   Oncology Letters

IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel

(2015) Zhen Ning Wee et al.   Nature Communications

NOVA1 inhibition by miR-146b-5p in the remnant tissue microenvironment defines occult residual disease after gastric cancer removal

(2015) Sun Och Yoon et al.   Oncotarget

NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor

(2015) Elena Galvani et al.   Oncotarget

IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer

(2015) Yi-Nan Liu et al.   Oncotarget

NF-κB-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer

(2015) Collin M. Blakely et al.   Cell Reports

Emerging Roles of MicroRNAs in EGFR-Targeted Therapies for Lung Cancer

(2015) Fei Han et al.   Biomed Research International

MiR-130a Overcomes Gefitinib Resistance by Targeting Met in Non-Small Cell Lung Cancer Cell Lines

(2014) Yong-Ming Zhou et al.   Asian Pacific Journal of Cancer Prevention

miR-138-5p reverses gefitinib resistance in non-small cell lung cancer cells via negatively regulating G protein-coupled receptor 124

(2014) Yi Gao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IRAK signalling in cancer

(2014) G W Rhyasen et al.   BRITISH JOURNAL OF CANCER

Comparison of Clinical Outcomes Following Gefitinib and Erlotinib Treatment in Non–Small-Cell Lung Cancer Patients Harboring an Epidermal Growth Factor Receptor Mutation in Either Exon 19 or 21

(2014) Sung Hee Lim et al.   Journal of Thoracic Oncology

miR-146b-5p inhibits glioma migration and invasion by targeting MMP16

(2013) Yanyan Li et al.   CANCER LETTERS

MicroRNA-133b inhibits the growth of non-small-cell lung cancer by targeting the epidermal growth factor receptor

(2012) Lingxiang Liu et al.   FEBS Journal

Activation of IL-6R/JAK1/STAT3 Signaling Induces De Novo Resistance to Irreversible EGFR Inhibitors in Non-Small Cell Lung Cancer with T790M Resistance Mutation

(2012) S. M. Kim et al.   MOLECULAR CANCER THERAPEUTICS

MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib

(2012) Ming-Hung Huang et al.   Molecular Oncology

MicroRNAs in metabolism and metabolic disorders

(2012) Veerle Rottiers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR

(2011) Trever G. Bivona et al.   NATURE

Slug Confers Resistance to the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

(2010) Tzu-Hua Chang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Requirement of the NF-κB Subunit p65/RelA for K-Ras–Induced Lung Tumorigenesis

(2010) Daniela S. Bassères et al.   CANCER RESEARCH

miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death

(2010) L. Galluzzi et al.   CANCER RESEARCH

MicroRNAs as Regulators of Differentiation and Cell Fate Decisions

(2010) Kathryn N. Ivey et al.   Cell Stem Cell

Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor

(2010) D Ercan et al.   ONCOGENE

MicroRNAs in Cancer: Small Molecules With a Huge Impact

(2009) Marilena V. Iorio et al.   JOURNAL OF CLINICAL ONCOLOGY

Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma

(2009) Etienne Meylan et al.   NATURE

microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma

(2008) B. Kefas et al.   CANCER RESEARCH