Irisin Protects Against Motor Dysfunction of Rats with Spinal Cord Injury via Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase-Nuclear Factor Kappa-B Pathway

A novel hydrogel-based treatment for complete transection spinal cord injury repair is driven by microglia/macrophages repopulation

(2020) Dezun Ma et al.   BIOMATERIALS

Sirtuin4 suppresses the anti‐neuroinflammatory activity of infiltrating regulatory T cells in the traumatically injured spinal cord

(2019) Wenping Lin et al.   IMMUNOLOGY

Serial plasma DNA levels as predictors of outcome in patients with acute traumatic cervical spinal cord injury

(2019) Hung-Chen Wang et al.   Journal of Translational Medicine

Irisin attenuates intestinal injury, oxidative and endoplasmic reticulum stress in mice with L-arginine-induced acute pancreatitis

(2019) Yi-Fan Ren et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Inflammation-induced lymphatic architecture and bone turnover changes are ameliorated by irisin treatment in chronic inflammatory bowel disease

(2018) S. Anand Narayanan et al.   FASEB JOURNAL

Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

(2018) Hong‑Yu Meng et al.   Molecular Medicine Reports

A glance at the therapeutic potential of irisin against diseases involving inflammation, oxidative stress, and apoptosis: An introductory review

(2018) Hassan Askari et al.   PHARMACOLOGICAL RESEARCH

The protective effect of Irisin against ischemia-reperfusion injury after perforator flap grafting in rats

(2018) Gang Zhao et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Irisin promotes cardiac progenitor cell-induced myocardial repair and functional improvement in infarcted heart

(2018) Yu Tina Zhao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Irisin inhibits pancreatic cancer cell growth via the AMPK-mTOR pathway

(2018) Jiayu Liu et al.   Scientific Reports

Fucoxanthin prevents lipopolysaccharide-induced depressive-like behavior in mice via AMPK- NF-κB pathway

(2018) Xi Jiang et al.   METABOLIC BRAIN DISEASE

The Role of Irisin in Alzheimer’s Disease

(2018) Oh Kim et al.   Journal of Clinical Medicine

Irisin protects against neuronal injury induced by oxygen-glucose deprivation in part depends on the inhibition of ROS-NLRP3 inflammatory signaling pathway

(2017) Juan Peng et al.   MOLECULAR IMMUNOLOGY

Using NGF heparin-poloxamer thermosensitive hydrogels to enhance the nerve regeneration for spinal cord injury

(2016) Ying-Zheng Zhao et al.   Acta Biomaterialia

Irisin protects against endothelial injury and ameliorates atherosclerosis in apolipoprotein E-Null diabetic mice

(2015) Junyan Lu et al.   ATHEROSCLEROSIS

Epidemiology of Spinal Cord Injury in Iran: Discrepancy with International and Previous Institutional Reports

(2015) Hooshang Saberi et al.   NEUROEPIDEMIOLOGY

Effect of carnosine, methylprednisolone and their combined application on irisin levels in the plasma and brain of rats with acute spinal cord injury

(2015) Serdal Albayrak et al.   NEUROPEPTIDES

Three-dimensional imaging of microvasculature in the rat spinal cord following injury

(2015) Yong Cao et al.   Scientific Reports

Early molecular and behavioral response to lipopolysaccharide in the WAG/Rij rat model of absence epilepsy and depressive-like behavior, involves interplay between AMPK, AKT/mTOR pathways and neuroinflammatory cytokine release

(2014) Emilio Russo et al.   BRAIN BEHAVIOR AND IMMUNITY

Irisin: ‘fat’ or artefact

(2014) A.B. Crujeiras et al.   CLINICAL ENDOCRINOLOGY

Plasma irisin levels progressively increase in response to increasing exercise workloads in young, healthy, active subjects

(2014) Stella S Daskalopoulou et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Exercise-Induced Irisin Secretion Is Independent of Age or Fitness Level and Increased Irisin May Directly Modulate Muscle Metabolism Through AMPK Activation

(2014) Joo Young Huh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Three new players in energy regulation: Preptin, adropin and irisin

(2014) Suleyman Aydin   PEPTIDES

Effect of obesity and exercise on the expression of the novel myokines, Myonectin and Fibronectin type III domain containing 5

(2014) Jonathan M. Peterson et al.   PeerJ

Ferulic acid increases pain threshold and ameliorates depression-like behaviors in reserpine-treated mice: behavioral and neurobiological analyses

(2013) Ying Xu et al.   METABOLIC BRAIN DISEASE

Regulation of Autophagy and Ubiquitinated Protein Accumulation by bFGF Promotes Functional Recovery and Neural Protection in a Rat Model of Spinal Cord Injury

(2013) Hong-Yu Zhang et al.   MOLECULAR NEUROBIOLOGY

Caspase inhibition augments Dichlorvos-induced dopaminergic neuronal cell death by increasing ROS production and PARP1 activation

(2013) W.Y. Wani et al.   NEUROSCIENCE

From basics to clinical: A comprehensive review on spinal cord injury

(2013) Nuno A. Silva et al.   PROGRESS IN NEUROBIOLOGY

FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise

(2012) Joo Young Huh et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Incidence and Prevalence of Spinal Cord Injury in Canada: A National Perspective

(2012) Vanessa K. Noonan et al.   NEUROEPIDEMIOLOGY

AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network

(2011) Antero Salminen et al.   AGEING RESEARCH REVIEWS

Functional assessment after sciatic nerve injury in a rat model

(2009) Paul Dinh et al.   MICROSURGERY

Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis

(2009) Constanze Csaki et al.   ARTHRITIS RESEARCH & THERAPY