Journal
MICROMACHINES
Volume 12, Issue 2, Pages -Publisher
MDPI
DOI: 10.3390/mi12020117
Keywords
microneedles; 3D printing; stereolithography; optimisation; inkjet coating
Ask authors/readers for more resources
This work focuses on the optimization of 3D-printed microneedles, exploring the key relationships between design and manufacturing parameters and quality and performance. It was demonstrated that microneedle geometry affects behavior and drug delivery efficiency.
3D printing has emerged as a powerful manufacturing technology and has attracted significant attention for the fabrication of microneedle (MN)-mediated transdermal systems. In this work, we describe an optimisation strategy for 3D-printed MNs, ranging from the design to the drug delivery stage. The key relationships between design and manufacturing parameters and quality and performance are systematically explored. The printing and post-printing set parameters were found to influence quality and material mechanical properties, respectively. It was demonstrated that the MN geometry affected piercing behaviour, fracture, and coating morphology. The delivery of insulin in porcine skin by inkjet-coated MNs was shown to be influenced by MN design.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available