4.2 Article

FFU-Net: Feature Fusion U-Net for Lesion Segmentation of Diabetic Retinopathy

Journal

BIOMED RESEARCH INTERNATIONAL
Volume 2021, Issue -, Pages -

Publisher

HINDAWI LTD
DOI: 10.1155/2021/6644071

Keywords

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Funding

  1. Young Scientists Fund of the National Natural Science Foundation of China [61802300]
  2. China Postdoctoral Science Foundation [2018m643666]
  3. Xi'an Jiaotong University basic research foundation for Young Teachers [xjh012019043]
  4. National Key Research and Development Project [2019YFB2102501, 2019YFB2103005]

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This paper proposed a new lesion segmentation model FFU-Net that enhances the U-Net model by incorporating multiscale feature fusion and a Balanced Focal Loss function. Experimental results on benchmark dataset IDRID showed that FFU-Net outperformed several state-of-the-art models in the task of lesion segmentation for diabetic retinopathy.
Diabetic retinopathy is one of the main causes of blindness in human eyes, and lesion segmentation is an important basic work for the diagnosis of diabetic retinopathy. Due to the small lesion areas scattered in fundus images, it is laborious to segment the lesion of diabetic retinopathy effectively with the existing U-Net model. In this paper, we proposed a new lesion segmentation model named FFU-Net (Feature Fusion U-Net) that enhances U-Net from the following points. Firstly, the pooling layer in the network is replaced with a convolutional layer to reduce spatial loss of the fundus image. Then, we integrate multiscale feature fusion (MSFF) block into the encoders which helps the network to learn multiscale features efficiently and enrich the information carried with skip connection and lower-resolution decoder by fusing contextual channel attention (CCA) models. Finally, in order to solve the problems of data imbalance and misclassification, we present a Balanced Focal Loss function. In the experiments on benchmark dataset IDRID, we make an ablation study to verify the effectiveness of each component and compare FFU-Net against several state-of-the-art models. In comparison with baseline U-Net, FFU-Net improves the segmentation performance by 11.97%, 10.68%, and 5.79% on metrics SEN, IOU, and DICE, respectively. The quantitative and qualitative results demonstrate the superiority of our FFU-Net in the task of lesion segmentation of diabetic retinopathy.

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