Article
Biochemistry & Molecular Biology
Yu Ding, Haotian Ma, Xin Liu, Shengxue Qin, Jie Liu, Guanhang Qu, Yaozong Bai, Lifen Zhao
Summary: By synthesizing reactive isocyanate-modified graphene oxide (mGO) as an enhancer, the mechanical properties of PLA/PEG blends were successfully improved. The performance of the interface was enhanced by the formation of polyurethane (PU) between GO and the matrix. Moreover, the in situ formed PU also improved the relaxation time of molecule motion, leading to better shape-memory recovery rate and final recovery degree of the composites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Kenta Hashimoto, Naruki Kurokawa, Atsushi Hotta
Summary: New biodegradable shape-memory polymers (SMPs) were synthesized by blending PLCL and sc-PLA, showing controllable switching temperatures and shape-recovery ratios. The SMPs can be used as biomaterials for medical devices.
Article
Polymer Science
Huimin Zhou, Ying Xia, Guangqing Mu, Yuanmei Gao, Si Liang, Guozhong Li, Qian Yang, Xiaojian Lin, Fang Qian
Summary: Biodegradable thermoresponsive shape memory blends with reversible phase PCL and fixed phase PLA were prepared by melt blending. PLA positively affects shape memory properties, while having little impact on high temperature stability, demonstrated by increased balance torque and entanglement of macromolecular chains. As a result, a physical crosslinking network is formed by the entanglement of microcrystals and macromolecules.
JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY
(2021)
Article
Polymer Science
Yazgan Mete, Konstanze Seidler, Christian Gorsche, Thomas Koch, Patrick Knaack, Robert Liska
Summary: This study presents a novel approach to 3D print polyesters directly from ε-caprolactone via stereolithography at elevated temperatures. The introduction of low amounts of crosslinkers improves the stability of the structure while maintaining its degradability and semicrystallinity. The study also highlights the significant influence of the amount and type of crosslinker on the material properties.
POLYMER INTERNATIONAL
(2022)
Article
Polymer Science
Xiao-Wen Zhou, Jing Huang, Xu-Hui Zhang, Ting Li, Yang Wang, Shi-Bo Wang, Bi-Hua Xia, Wei-Fu Dong
Summary: In this study, exchangeable hydroxyl-ester crosslinks were introduced into PLA/PBAT blends through reactive blending. The interfacial adhesion between PLA and PBAT was greatly improved by the reaction between a tertiary amine-containing polyol (BTM) and 4,4 '-diphenylmethane diisocyanate (MDI). The PLA/PBAT blends showed enhanced heat resistance and toughness while maintaining high stiffness, thanks to the network structure formed by the crosslinks.
CHINESE JOURNAL OF POLYMER SCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Ziting Zhou, Yue Meng, Cong Wei, Ying Bai, Xiaoying Wang, Daping Quan, Jing Zhou
Summary: This article introduces a linear shape memory biodegradable polyester without chemical crosslinks or multiblock structures, with a new programming protocol to split crystals into two parts with different melting transitions. The split crystals play different roles in fixation and recovery, impacting the fixed rate and recovery rate. The shape memory performance can be optimized by controlling the ratio of partitioned crystals and pre-stretching of the sample.
MACROMOLECULAR MATERIALS AND ENGINEERING
(2021)
Article
Polymer Science
Guangqin Shi, Cheng Huang, Xinyu Cao, Minying Liu, Jingnan Zhang, Kun Zheng, Yongmei Ma
Summary: A triple-shape memory polymer was prepared by chemically crosslinking melting blending of ethylene-vinyl acetate copolymer (EVA) and poly(propylene carbonate) (PPC), showing excellent triple shape memory effects with shape fixing ratio and shape recovery ratio both over 90%. The key to achieving triple SME is the matching of the modulus of the two components, with the glassy PPC having a higher modulus than the semi-crystalline EVA.
Article
Polymer Science
Brenda G. Molina, Guillermo Ocon, Fiorella M. Silva, Jose I. Iribarren, Elaine Armelin, Carlos Aleman
Summary: This study presents an investigation on the shape memory effect of extruded polylactic acid (PLA) and polycaprolactone (PCL) blends. The blends were transformed into films and movable components of articulated specimens using hot pressing and 3D printing. The chemical structure, wettability, thermal properties, and mechanical response of the blends were evaluated and compared with neat PLA and PCL.
EUROPEAN POLYMER JOURNAL
(2023)
Review
Biochemistry & Molecular Biology
Marius Stelian Popa, Adriana Nicoleta Frone, Denis Mihaela Panaitescu
Summary: This review provides a comprehensive overview of the preparation, properties, and application of Poly (3-hydroxybutyrate) (PHB) blends with other biodegradable polymers. The focus is on the compatibility of PHB with other polymers and the methods used to improve dispersion and interface. The changes in PHB morphology, thermal, mechanical, and barrier properties induced by the second polymer are critically analyzed. The review also summarizes the biodegradability and recyclability strategies of PHB blends, along with the processing techniques adapted to the intended application.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Huijie Zuo, Juyang Liu, Dong Huang, Yuanbin Bai, Liang Cui, Li Pan, Kunyu Zhang, Huaiyuan Wang
Summary: High-performance sustainable ternary blends were prepared using a melt blending method with completely biodegradable polyesters, showing improved mechanical properties due to the addition of flexible PPC and P34HB phases with effective interfacial compatibilization.
JOURNAL OF POLYMER SCIENCE
(2021)
Article
Polymer Science
Magdalena Zieba, Jakub Wlodarczyk, Abhishek Gupta, Malgorzata Pastusiak, Pawel Chaber, Henryk Janeczek, Marta Musiol, Wanda Sikorska, Bozena Kaczmarczyk, Izabela Radecka, Marek Kowalczuk, Arunas Savickas, Nijole Savickiene, Grazyna Adamus
Summary: This study utilized proanthocyanidins extracted from Pelargonium sidoides to prepare polymeric delivery systems with antimicrobial activity for potential use as wound dressings. Biodegradable dressings were constructed using poly(D,L-lactide) and atactic poly[(R,S)-3-hydroxybutyrate], and P(D,L)LA/a-PHB blends were characterized and tested for PCAN release and cytotoxicity, demonstrating their potential application in wound dressings.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Polymer Science
P. A. Zhukova, F. S. Senatov, M. Yu Zadorozhnyy, N. S. Chmelyuk, V. A. Zaharova
Summary: This study achieved a reduction in the activation initiation temperature and activation energy of shape memory effect (SME) by forming a composite based on PLA containing 10% poly (epsilon-caprolactone) (PCL), providing a safe and effective material for temporary self-fitting scaffolds in reconstructive surgery.
Article
Polymer Science
Polina A. Kovaleva, Igor O. Pariy, Roman V. Chernozem, Mikhail Yu. Zadorozhnyy, Elizaveta S. Permyakova, Evgeniy A. Kolesnikov, Maria A. Surmeneva, Roman A. Surmenev, Fedor S. Senatov
Summary: In this study, the electrospun PLA-PCL scaffolds were extensively characterized to investigate the impact of reduced graphene oxide (rGO) content on morphology, structure, thermal behavior, and shape memory performance. The results showed that the addition of rGO led to changes in the structure and improved mechanical properties of the prepared composites. The electrospun hybrid PLA-PCL scaffolds with rGO exhibited pronounced shape memory effect, making them promising for tissue engineering applications.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Nevena Pounovic, Jessica Marbach, Yinyin Bao, Valentine Berger, Karina Klein, Sarah Schleich, Fergal Brian Coulter, Nicole Kleger, Andre R. Studart, Daniel Franzen, Zhi Luo, Jean-Christophe Leroux
Summary: Digital light processing (DLP) 3D printing is a promising technique for rapid manufacturing of precise customized medical devices. However, the development of suitable photopolymerizable materials is still a challenge. In this study, a multifunctional DLP printed material system based on gold nanorods and polyester copolymer is reported, demonstrating robust near-infrared responsiveness and shape transformation.
Article
Materials Science, Characterization & Testing
Marta Safandowska, Artur Rozanski
Summary: This paper analyzed the influence of different aspects of crystallization process on the formation of ring-banded spherulites in polylactide. It was found that the banding phenomenon in polylactide depends on the degree of supercooling and there is a direct correlation between band space and degree of supercooling. Additionally, the inclusion of triethyl citrate in polylactide matrix affects the range in which banded spherulites appear, but does not change the required supercooling degree.
Article
Engineering, Biomedical
Magdalena Antonowicz, Janusz Szewczenko, Anita Kajzer, Wojciech Kajzer, Joanna Jaworska, Katarzyna Jelonek, Paulina Karpeta-Jarzabek, Piotr Bryniarski, Maciej Krzywiecki, Lucyna Grzadziel, Andrzej S. Swinarew, Damian S. Nakonieczny, Janusz Kasperczyk
Summary: This study investigates the impact of applying a diastolic biodegradable coating to ureteral stents, as well as its application in the physical and chemical properties of the stents, aiming to reduce complications after implantation of ureteral stents.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2022)
Article
Polymer Science
Joanna Jaworska, Mateusz Stojko, Jakub Wlodarczyk, Henryk Janeczek, Marcin Godzierz, Monika Musial-Kulik, Piotr Bryniarski, Janusz Kasperczyk
Summary: The study aims to 3D print tubular biodegradable scaffolds as a model prostatic stent, with the ability to add chemotherapy drugs for local delivery. After 6 weeks of incubation, the scaffolds showed stable chain microstructure changes, low weight loss, and slow release of docetaxel. The results suggest that local chemotherapeutic delivery is advantageous compared to current systemic administration methods.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Engineering, Biomedical
Jakub Wlodarczyk, Mateusz Stojko, Monika Musial-Kulik, Paulina Karpeta-Jarzabek, Malgorzata Pastusiak, Henryk Janeczek, Piotr Dobrzynski, Michal Sobota, Janusz Kasperczyk
Summary: A dual-jet electrospinning technique was used to mix hydrophilic and biodegradable polymers, resulting in partially degradable nonwovens. The hydrophilicity of the nanofibers was found to affect the degradation mechanism and rate, as well as the physical interactions between the nonwovens and the degradation environment. This method provides a way to control the degradation of polyester without changing its chemical composition, making it promising for biomedical applications.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Marta Musiol, Joanna Rydz, Henryk Janeczek, Aleksandra Kordyka, Jacek Andrzejewski, Tomasz Sterzynski, Sebastian Jurczyk, Mariana Cristea, Krzysztof Musiol, Marian Kampik, Marek Kowalczuk
Summary: Biochar was introduced as a filler in the blend of aliphatic-aromatic copolyester and polylactide, leading to changes in properties and degradation behavior of the materials. Increasing biochar content reduced surface resistivity significantly and impacted the electrostatic properties of the composites. The addition of biochar also resulted in surface cracks during degradation tests, but did not significantly influence the thermal properties of the polymer matrix.
MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS
(2022)
Article
Polymer Science
Joanna Jaworska, Michal Sobota, Malgorzata Pastusiak, Michal Kawalec, Henryk Janeczek, Piotr Rychter, Kamila Lewicka, Piotr Dobrzynski
Summary: This work presents the results of research on the preparation of bioresorbable functional polyestercarbonates containing side carboxyl groups. The simplified one-step method allows obtaining copolymers with all carbonate units containing carboxyl groups, avoiding the issue of heavy metals residue from the traditional method.
Review
Biochemistry & Molecular Biology
Magdalena Jurczyk, Janusz Kasperczyk, Dorota Wrzesniok, Artur Beberok, Katarzyna Jelonek
Summary: There is a growing interest in the use of chemosensitizers and cytostatics in combination to overcome cancer resistance to treatment. To overcome challenges such as poor bioavailability and chemical instability of drugs, attempts have been made to create nanoparticles for the delivery of docetaxel (Dtx) and resveratrol (Res). Recent reports suggest that nano-delivery systems for Dtx and Res exhibit better efficiency in cancer treatment than free drugs, and the simultaneous release of both drugs in cancer cells may help overcome limitations caused by multidrug resistance.
Review
Biochemistry & Molecular Biology
Anna Smola-Dmochowska, Kamila Lewicka, Alicja Macyk, Piotr Rychter, Elzbieta Pamula, Piotr Dobrzynski
Summary: Antibiotic resistance is a major global health and food security threat. The development of new antimicrobial therapeutics and antibacterial packaging materials is crucial for preventing and treating infectious diseases. This review highlights the significant research activities conducted in recent years in the field of polymeric materials and polymer composites with antibacterial properties.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Iwona Pudelko, Anna Moskwik, Konrad Kwiecien, Sven Kriegseis, Malgorzata Krok-Borkowicz, Karolina Schickle, Dorota Ochonska, Piotr Dobrzynski, Monika Brzychczy-Wloch, Jesus Gonzalez-Julian, Elzbieta Pamula
Summary: Implant-related infections are a global challenge, and new solutions are being investigated to overcome conventional therapy failures. In this study, porous zirconia scaffolds were manufactured and coated with antibiotic-loaded polymer nanoparticles to enhance bioactivity and achieve antibacterial effects. The scaffolds exhibited high encapsulation efficiency and drug loading, and showed excellent cytocompatibility and antimicrobial properties.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Polymer Science
Natalia Smigiel-Gac, Anna Smola-Dmochowska, Henryk Janeczek, Piotr Dobrzynski
Summary: The article presents the synthesis and characteristics of amphiphilic block terpolymers consisting of a hydrophilic polyesteramine block and hydrophobic blocks made of lactidyl and glycolidyl units. These terpolymers were obtained through copolymerization of L-lactide with glycolide using macroinitiators with protected amine and hydroxyl groups. The terpolymers were designed to have biodegradability, biocompatibility, antibacterial properties, and high surface wettability by water. The properties of the terpolymers, such as molecular mass, contact angle, crystallinity, and melting behavior, were evaluated using various tests.
Article
Chemistry, Multidisciplinary
Justyna Wilinska, Artur Turek, Jakub Rech, Henryk Janeczek, Malgorzata Pastusiak, Aleksandra Kordyka, Aleksandra Borecka, Magdalena Kobielarz, Janusz Kasperczyk
Summary: This study aimed to develop long-acting injections of aripiprazole using hot melt extrusion. Different polymers were used to prepare two types of rods, and their properties were analyzed using various methods. The results suggested that one rod is suitable for intramuscular administration and the other for subcutaneous administration.
APPLIED SCIENCES-BASEL
(2023)
