Molecular and biophysical mechanisms behind the enhancement of lung surfactant function during controlled therapeutic hypothermia

In Vitro Functional and Structural Characterization of A Synthetic Clinical Pulmonary Surfactant with Enhanced Resistance to Inhibition

(2020) Mercedes Echaide et al.   Scientific Reports

Surfactant Injury in the Early Phase of Severe Meconium Aspiration Syndrome

(2020) Chiara Autilio et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Synthetic Surfactant CHF5633 Compared with Poractant Alfa in the Treatment of Neonatal Respiratory Distress Syndrome: A Multicenter, Double-Blind, Randomized, Controlled Clinical Trial

(2020) Rangasamy Ramanathan et al.   JOURNAL OF PEDIATRICS

Effect of cooling on lung secretory phospholipase A2 activity in vitro, ex vivo and in vivo

(2019) Chiara Autilio et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Acute respiratory distress syndrome

(2019) Michael A. Matthay et al.   Nature Reviews Disease Primers

Influence of temperature on dynamic surface properties of spread DPPC monolayers in a broad range of surface pressures

(2019) A.G. Bykov et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Surfactant Dysfunction in ARDS and Bronchiolitis is Repaired with Cyclodextrins

(2018) Mustafa Al-Saiedy et al.   MILITARY MEDICINE

Controlled hypothermia may improve surfactant function in asphyxiated neonates with or without meconium aspiration syndrome

(2018) Chiara Autilio et al.   PLoS One

Induced hypothermia in patients with septic shock and respiratory failure (CASS): a randomised, controlled, open-label trial

(2018) Theis Skovsgaard Itenov et al.   Lancet Respiratory Medicine

Phenotypes in acute respiratory distress syndrome

(2018) Pratik Sinha et al.   Current Opinion in Critical Care

Is Therapeutic Hypothermia for Acute Respiratory Distress Syndrome the Future?

(2017) Adam J. Hayek et al.   JOURNAL OF INTENSIVE CARE MEDICINE

Effect of Whole Body Hypothermia on Surfactant Function When Amniotic Fluid is Meconium Stained

(2017) Chiara Autilio et al.   Therapeutic Hypothermia and Temperature Management

Fever Is Associated with Reduced, Hypothermia with Increased Mortality in Septic Patients: A Meta-Analysis of Clinical Trials

(2017) Zoltan Rumbus et al.   PLoS One

Hypothermia and Meconium Aspiration Syndrome: International Multicenter Retrospective Cohort Study

(2016) Daniele De Luca et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Does Whole-Body Hypothermia in Neonates with Hypoxic–Ischemic Encephalopathy Affect Surfactant Disaturated-Phosphatidylcholine Kinetics?

(2016) Matteo Nespeca et al.   PLoS One

Distinct Molecular Phenotypes of Direct vs Indirect ARDS in Single-Center and Multicenter Studies

(2015) Carolyn S. Calfee et al.   CHEST

Detailed Analysis of the Surface Area and Elasticity in the Saturated 1,2-Diacylphosphatidylcholine/Cholesterol Binary Monolayer System

(2015) Tsubasa Miyoshi et al.   LANGMUIR

Effect of whole body hypothermia on inflammation and surfactant function in asphyxiated neonates: Figure 1–

(2014) Daniele De Luca et al.   EUROPEAN RESPIRATORY JOURNAL

Effect of Therapeutic Hypothermia on Gas Exchange and Respiratory Mechanics: A Retrospective Cohort Study

(2014) Lioudmila V. Karnatovskaia et al.   Therapeutic Hypothermia and Temperature Management

Adaptations to hibernation in lung surfactant composition of 13-lined ground squirrels influence surfactant lipid phase segregation properties

(2013) Lakshmi N.M. Suri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mild hypothermia increases pulmonary anti-inflammatory response during protective mechanical ventilation in a piglet model of acute lung injury

(2013) Pablo Cruces et al.   PEDIATRIC ANESTHESIA

Adaptation to low body temperature influences pulmonary surfactant composition thereby increasing fluidity while maintaining appropriately ordered membrane structure and surface activity

(2012) Lakshmi N.M. Suri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Exposure to Polymers Reverses Inhibition of Pulmonary Surfactant by Serum, Meconium, or Cholesterol in the Captive Bubble Surfactometer

(2012) Elena López-Rodríguez et al.   BIOPHYSICAL JOURNAL

Neuroprotection and Hypothermia in Infants and Children

(2012) Domenico Pietrini et al.   CURRENT DRUG TARGETS

Secretory Phospholipase A2-Mediated Depletion of Phosphatidylglycerol in Early Acute Respiratory Distress Syndrome

(2011) David L. Long et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Combined and Independent Action of Proteins SP-B and SP-C in the Surface Behavior and Mechanical Stability of Pulmonary Surfactant Films

(2010) David Schürch et al.   BIOPHYSICAL JOURNAL

Body temperature effects on lung injury in ventilated preterm lambs

(2010) Molly K. Ball et al.   RESUSCITATION

Methyl-β-cyclodextrin restores the structure and function of pulmonary surfactant films impaired by cholesterol

(2009) Lasantha C. Gunasekara et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A double injection ADSA-CSD methodology for lung surfactant inhibition and reversal studies

(2009) Sameh M.I. Saad et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Surface Rheology and Phase Transitions of Monolayers of Phospholipid/Cholesterol Mixtures

(2008) Marcel Vrânceanu et al.   BIOPHYSICAL JOURNAL

The biophysical function of pulmonary surfactant

(2008) Sandra Rugonyi et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

A comparative study of mechanisms of surfactant inhibition

(2007) Lasantha Gunasekara et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES