The retinal toxicity profile towards assemblies of Amyloid-β indicate the predominant pathophysiological activity of oligomeric species
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Title
The retinal toxicity profile towards assemblies of Amyloid-β indicate the predominant pathophysiological activity of oligomeric species
Authors
Keywords
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Journal
Scientific Reports
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-12-01
DOI
10.1038/s41598-020-77712-9
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Note: Only part of the references are listed.- Protein misfolding, aggregation and mechanism of amyloid cytotoxicity: An overview and therapeutic strategies to inhibit aggregation
- (2019) Masihuz Zaman et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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- (2018) Heejung Chun et al. NEUROSCIENCE RESEARCH
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- (2017) JArjuna Ratnayaka et al. Neural Regeneration Research
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- (2017) Junran Sun et al. Cell Death & Disease
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- (2017) Annamalai Prakasam et al. JOURNAL OF ALZHEIMERS DISEASE
- Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice
- (2017) Tuhina Prasad et al. Scientific Reports
- Dementia of the eye: the role of amyloid beta in retinal degeneration
- (2015) J A Ratnayaka et al. EYE
- Subretinal injection of amyloid-β peptide accelerates RPE cell senescence and retinal degeneration
- (2014) CHAOQI LIU et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
- (2014) Wan Ling Wong et al. Lancet Global Health
- Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism
- (2013) S. I. A. Cohen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Elevated amyloid β production in senescent retinal pigment epithelium, a possible mechanism of subretinal deposition of amyloid β in age-related macular degeneration
- (2012) Jiying Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Amyloid Precursor Protein Is Required for Normal Function of the Rod and Cone Pathways in the Mouse Retina
- (2012) Tracy Ho et al. PLoS One
- Development and Expression of Amyloid-β Peptide 42 in Retinal Ganglion Cells in Rats
- (2011) Jianqiang Wang et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Parallel findings in age-related macular degeneration and Alzheimer’s disease
- (2011) Kyoko Ohno-Matsui PROGRESS IN RETINAL AND EYE RESEARCH
- Viewing Ageing Eyes: Diverse Sites of Amyloid Beta Accumulation in the Ageing Mouse Retina and the Up-Regulation of Macrophages
- (2010) Jaimie Hoh Kam et al. PLoS One
- SAFETY EVALUATION OF REPEATED INTRAVITREAL INJECTIONS OF BEVACIZUMAB AND RANIBIZUMAB IN RABBIT EYES
- (2010) SHIRI ZAYIT-SOUDRY et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Amyloid-β(1-42) alters structure and function of retinal pigmented epithelial cells
- (2009) Julien Bruban et al. AGING CELL
- Forecasting Age-Related Macular Degeneration Through the Year 2050
- (2009) David B. Rein ARCHIVES OF OPHTHALMOLOGY
- Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer’s disease
- (2009) R. Michael Dutescu et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Amyloid-β up-regulates complement factor B in retinal pigment epithelial cells through cytokines released from recruited macrophages/microglia: Another mechanism of complement activation in age-related macular degeneration
- (2009) Jiying Wang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Photoreceptor Layer Thinning over Drusen in Eyes with Age-Related Macular Degeneration Imaged In Vivo with Spectral-Domain Optical Coherence Tomography
- (2009) Stefanie G. Schuman et al. OPHTHALMOLOGY
- Prematurely senescent ARPE-19 cells display features of age-related macular degeneration
- (2008) Anne-Lise Glotin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
- (2008) Ganesh M Shankar et al. NATURE MEDICINE
- Aβ deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease
- (2008) V.L. Villemagne et al. NEUROPSYCHOLOGIA
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