Histone demethylase JMJD2B/KDM4B regulates transcriptional program via distinctive epigenetic targets and protein interactors for the maintenance of trophoblast stem cells

IL-6 and sIL-6R induces STAT3-dependent differentiation of human VSMCs into osteoblast-like cells through JMJD2B-mediated histone demethylation of RUNX2

(2019) Akira Kurozumi et al.   BONE

Targeting of Histone Demethylases KDM5A and KDM6B Inhibits the Proliferation of Temozolomide-Resistant Glioblastoma Cells

(2019) Massimo Romani et al.   Cancers

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth

(2018) Janet K. Parrish et al.   Oncotarget

Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self‐renewal and early development

(2016) Marianne Terndrup Pedersen et al.   EMBO JOURNAL

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks

(2015) Paulina A. Latos et al.   GENES & DEVELOPMENT

Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases

(2015) John R. Horton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells

(2015) Paulina A. Latos et al.   Nature Communications

The Demethylase JMJD2C Localizes to H3K4me3-Positive Transcription Start Sites and Is Dispensable for Embryonic Development

(2014) M. T. Pedersen et al.   MOLECULAR AND CELLULAR BIOLOGY

Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells

(2014) Dongmei Zhu et al.   Nature Communications

LSD1 promotes oxidative metabolism of white adipose tissue

(2014) Delphine Duteil et al.   Nature Communications

Finding the active genes in deep RNA-seq gene expression studies

(2013) Traver Hart et al.   BMC GENOMICS

Context-Dependent Wiring of Sox2 Regulatory Networks for Self-Renewal of Embryonic and Trophoblast Stem Cells

(2013) Kenjiro Adachi et al.   MOLECULAR CELL

Distinct and Combinatorial Functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in Mouse Embryonic Stem Cell Identity

(2013) Partha Pratim Das et al.   MOLECULAR CELL

Endogenous retroviruses function as species-specific enhancer elements in the placenta

(2013) Edward B Chuong et al.   NATURE GENETICS

A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth

(2013) Lei Wang et al.   Nature Communications

Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signaling

(2013) Amy Tsurumi et al.   Scientific Reports

Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation

(2013) Marc A Kerenyi et al.   eLife

Site-Specific Silencing of Regulatory Elements as a Mechanism of X Inactivation

(2012) J. Mauro Calabrese et al.   CELL

Histone Demethylases KDM4B and KDM6B Promotes Osteogenic Differentiation of Human MSCs

(2012) Ling Ye et al.   Cell Stem Cell

Enhancer decommissioning by LSD1 during embryonic stem cell differentiation

(2012) Warren A. Whyte et al.   NATURE

HP1a Targets the Drosophila KDM4A Demethylase to a Subset of Heterochromatic Genes to Regulate H3K36me3 Levels

(2012) Chia-Hui Lin et al.   PLoS One

Fetal growth: a review of terms, concepts and issues relevant to obstetrics

(2012) C. Mayer et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

AP-2γ regulates oestrogen receptor-mediated long-range chromatin interaction and gene transcription

(2011) Si Kee Tan et al.   EMBO JOURNAL

Histone Demethylase JMJD2B Functions as a Co-Factor of Estrogen Receptor in Breast Cancer Proliferation and Mammary Gland Development

(2011) Masahito Kawazu et al.   PLoS One

Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis

(2011) L. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A New Isoform of the Histone Demethylase JMJD2A/KDM4A Is Required for Skeletal Muscle Differentiation

(2011) Laure Verrier et al.   PLoS Genetics

Phosphatidylinositol 3 kinase modulation of trophoblast cell differentiation

(2010) Lindsey N. Kent et al.   BMC DEVELOPMENTAL BIOLOGY

PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-α target gene activation by regulating lysine demethylase 1 specificity

(2010) Sujit S Nair et al.   EMBO REPORTS

Regulation of adipogenesis by nucelar receptor PPARγ is modulated by the histone demethylase JMJD2C

(2010) Lizcano Fernando et al.   GENETICS AND MOLECULAR BIOLOGY

Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenance

(2010) B. L. Kidder et al.   GENOME RESEARCH

The Transcription Factor TCFAP2C/AP-2  Cooperates with CDX2 To Maintain Trophectoderm Formation

(2010) P. Kuckenberg et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphorylation of histone H3T6 by PKCβI controls demethylation at histone H3K4

(2010) Eric Metzger et al.   NATURE

Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo

(2010) P. J. Rugg-Gunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells

(2009) P. Yuan et al.   GENES & DEVELOPMENT

Placental and Embryonic Growth Restriction in Mice With Reduced Function Epidermal Growth Factor Receptor Alleles

(2009) J. Dackor et al.   GENETICS

KMT1E Mediated H3K9 Methylation is Required for the Maintenance of Embryonic Stem Cells by Repressing Trophectoderm Differentiation

(2009) Felix Lohmann et al.   STEM CELLS

Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5

(2008) Ray Kit Ng et al.   NATURE CELL BIOLOGY

De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

(2008) Silvina Epsztejn-Litman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Anti-Fas Activating Antibody Enhances Trophoblast Outgrowth on Endometrial Epithelial Cells by Induction of P38 MAPK/JNK-mediated Apoptosis

(2008) W.-L. Hsu et al.   PLACENTA

Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules

(2008) Q. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA