COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1

Gain Fat—Lose Metastasis: Converting Invasive Breast Cancer Cells into Adipocytes Inhibits Cancer Metastasis

(2019) Dana Ishay-Ronen et al.   CANCER CELL

The double edge sword of fibrosis in cancer

(2019) Chelsea Chandler et al.   Translational Research

A positive feedback loop bi-stably activates fibroblasts

(2018) So-Young Yeo et al.   Nature Communications

Collagen Type VI Alpha 3 Chain Promotes Epithelial-Mesenchymal Transition in Bladder Cancer Cells via Transforming Growth Factor β (TGF-β)/Smad Pathway

(2018) Yan Huang et al.   MEDICAL SCIENCE MONITOR

Adipose stromal cell targeting suppresses prostate cancer epithelial-mesenchymal transition and chemoresistance

(2018) Fei Su et al.   ONCOGENE

Paired related homeobox protein 1 regulates PDGF-induced chemotaxis of hepatic stellate cells in liver fibrosis

(2017) Jin Gong et al.   LABORATORY INVESTIGATION

Temporal Changes in Gene Expression Profile during Mature Adipocyte Dedifferentiation

(2017) Julie Anne Côté et al.   International Journal of Genomics

Role of the TGF-β pathway in dedifferentiation of human mature adipocytes

(2017) Julie Anne Côté et al.   FEBS Open Bio

Divergent functions of endotrophin on different cell populations in adipose tissue

(2016) Yueshui Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Prrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization

(2016) Shigetsugu Takano et al.   GENES & DEVELOPMENT

Reduced expression of collagen VI alpha 3 (COL6A3) confers resistance to inflammation-induced MCP1 expression in adipocytes

(2016) Stephane Gesta et al.   Obesity

Recessive Mutations in the α3 (VI) Collagen Gene COL6A3 Cause Early-Onset Isolated Dystonia

(2015) Michael Zech et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Adipocytes can induce epithelial-mesenchymal transition in breast cancer cells

(2015) YuKyung Lee et al.   BREAST CANCER RESEARCH AND TREATMENT

COL6A3 Is Regulated by Leptin in Human Adipose Tissue and Reduced in Obesity

(2015) Laura J. McCulloch et al.   ENDOCRINOLOGY

Stroma derived COL6A3 is a potential prognosis marker of colorectal carcinoma revealed by quantitative proteomics

(2015) Jie Qiao et al.   Oncotarget

Omental adipose tissue fibrosis and insulin resistance in severe obesity

(2015) V Guglielmi et al.   Nutrition & Diabetes

Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms

(2014) Melina Claussnitzer et al.   CELL

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

Production of Type VI Collagen by Human Macrophages: A New Dimension in Macrophage Functional Heterogeneity

(2014) M. Schnoor et al.   JOURNAL OF IMMUNOLOGY

COL6A3expression in adipocytes associates with insulin resistance and depends on PPARγ and adipocyte size

(2014) Simon N. Dankel et al.   Obesity

Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction

(2014) Kai Sun et al.   Nature Communications

Changes in adipose glucocorticoid metabolism before and after bariatric surgery assessed by direct hormone measurements

(2013) Paal Methlie et al.   Obesity

The Transcription Factor Paired-Related Homeobox 1 (Prrx1) Inhibits Adipogenesis by Activating Transforming Growth Factor-β (TGFβ) Signaling

(2012) Baowen Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipocyte-derived endotrophin promotes malignant tumor progression

(2012) Jiyoung Park et al.   JOURNAL OF CLINICAL INVESTIGATION

Selective Inhibition of Hypoxia-Inducible Factor 1  Ameliorates Adipose Tissue Dysfunction

(2012) K. Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

The TGFbeta Superfamily Signaling Pathway

(2012) Alexander Weiss et al.   Wiley Interdisciplinary Reviews-Developmental Biology

The nuclear receptors NUR77, NURR1 and NOR1 in obesity and during fat loss

(2011) V L Veum et al.   INTERNATIONAL JOURNAL OF OBESITY

Tumor-specific expression and alternative splicing of the COL6A3 gene in pancreatic cancer

(2011) Hwyda Arafat et al.   SURGERY

Defining macrophage phenotype and function in adipose tissue

(2011) Elise Dalmas et al.   TRENDS IN IMMUNOLOGY

Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation

(2010) Michael Spencer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fibrosis in Human Adipose Tissue: Composition, Distribution, and Link With Lipid Metabolism and Fat Mass Loss

(2010) A. Divoux et al.   DIABETES

Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data

(2010) Ahmed Essaghir et al.   NUCLEIC ACIDS RESEARCH

Switch from Stress Response to Homeobox Transcription Factors in Adipose Tissue After Profound Fat Loss

(2010) Simon N. Dankel et al.   PLoS One

Adipose Tissue Collagen VI in Obesity

(2009) Magdalena Pasarica et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A census of human transcription factors: function, expression and evolution

(2009) Juan M. Vaquerizas et al.   NATURE REVIEWS GENETICS

IPO8 and FBXL10: New Reference Genes for Gene Expression Studies in Human Adipose Tissue

(2009) Carmen Hurtado del Pozo et al.   Obesity

Homeobox Gene Prx1 Is Expressed in Activated Hepatic Stellate Cells and Transactivates Collagen α1(I) Promoter

(2008) Feng Jiang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI

(2008) T. Khan et al.   MOLECULAR AND CELLULAR BIOLOGY