Effects of Late-Life Caloric Restriction on Age-Related Alterations in the Rat Cortex and Hippocampus

Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging

(2020) Shuai Ma et al.   CELL

A Short‐Term Western Diet Impairs Cholesterol Homeostasis and Key Players of Beta Amyloid Metabolism in Brain of Middle Aged Rats

(2020) Maria Stefania Spagnuolo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Aging, Cellular Senescence, and Progressive Multiple Sclerosis

(2020) Dimitrios Papadopoulos et al.   Frontiers in Cellular Neuroscience

Metabolic regulation of aging and age-related disease

(2020) Mark W. Hamrick et al.   AGEING RESEARCH REVIEWS

ApoE Lipidation as a Therapeutic Target in Alzheimer’s Disease

(2020) Maria Fe Lanfranco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Maternal hypercaloric diet affects factors involved in lipid metabolism and the endogenous cannabinoid systems in the hypothalamus of adult offspring: sex-specific response of astrocytes to palmitic acid and anandamide

(2020) Patricia Rivera et al.   NUTRITIONAL NEUROSCIENCE

Sex-dimorphic Rostro-caudal Patterns of 5′-AMP-activated Protein Kinase Activation and Glucoregulatory Transmitter Marker Protein Expression in the Ventrolateral Ventromedial Hypothalamic Nucleus (VMNvl) in Hypoglycemic Male and Female Rats: Impact of Estradiol

(2020) Ayed A. Alshamrani et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

From discoveries in ageing research to therapeutics for healthy ageing

(2019) Judith Campisi et al.   NATURE

The effect of statins and the synthetic LXR agonist T0901317 on expression of ABCA1 transporter protein in human lung epithelial cell lines in vitro

(2019) Patrick He et al.   Pharmacological Reports

Two Behavioral Tests Allow a Better Correlation Between Cognitive Function and Expression of Synaptic Proteins

(2018) Marta Balietti et al.   Frontiers in Aging Neuroscience

Mitochondria, Estrogen and Female Brain Aging

(2018) Imane Lejri et al.   Frontiers in Aging Neuroscience

CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington’s disease

(2016) Lydie Boussicault et al.   BRAIN

Differential Regulation of Hippocampal IGF-1-Associated Signaling Proteins by Dietary Restriction in Aging Mouse

(2016) Ibanylla Kynjai Hynniewta Hadem et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Modulation of the Isoprenoid/Cholesterol Biosynthetic Pathway During Neuronal Differentiation In Vitro

(2016) Veronica Cartocci et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Rho GTPase signalling in cell migration

(2015) Anne J Ridley   CURRENT OPINION IN CELL BIOLOGY

Long-term dietary restriction differentially affects the expression of BDNF and its receptors in the cortex and hippocampus of middle-aged and aged male rats

(2014) Kosara Smiljanic et al.   BIOGERONTOLOGY

Cholesterol in brain disease: sometimes determinant and frequently implicated

(2014) M. G. Martin et al.   EMBO REPORTS

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Analysis of the protein network of cholesterol homeostasis in different brain regions: An age and sex dependent perspective

(2013) Marco Segatto et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Simvastatin Treatment Highlights a New Role for the Isoprenoid/Cholesterol Biosynthetic Pathway in the Modulation of Emotional Reactivity and Cognitive Performance in Rats

(2013) Marco Segatto et al.   NEUROPSYCHOPHARMACOLOGY

Metformin improves healthspan and lifespan in mice

(2013) Alejandro Martin-Montalvo et al.   Nature Communications

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

Axonal and dendritic synaptotagmin isoforms revealed by a pHluorin-syt functional screen

(2012) Camin Dean et al.   MOLECULAR BIOLOGY OF THE CELL

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB

(2011) William Mair et al.   NATURE

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

(2011) Grant R. Drummond et al.   NATURE REVIEWS DRUG DISCOVERY

Dietary restriction and aging, 2009

(2010) Subhash D. Katewa et al.   AGING CELL

Age- and sex-related differences in extra-hepatic low-density lipoprotein receptor

(2010) Marco Segatto et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Brain-Derived Neurotrophic Factor Is Associated with Age-Related Decline in Hippocampal Volume

(2010) K. I. Erickson et al.   JOURNAL OF NEUROSCIENCE

Expression of cholesterol homeostasis genes in the brain of the male rat is affected by age and dietary restriction

(2009) Milka Perovic et al.   BIOGERONTOLOGY

Sex differences in the subcellular distribution of angiotensin type 1 receptors and NADPH oxidase subunits in the dendrites of C1 neurons in the rat rostral ventrolateral medulla

(2009) J.P. Pierce et al.   NEUROSCIENCE

Hypercholesterolemia and 3-Hydroxy 3-Methylglutaryl Coenzyme A Reductase Regulation during Ageing

(2009) Laura Trapani et al.   TheScientificWorldJOURNAL