Article
Engineering, Environmental
Mohsen Jalali, Mahdi Jalali, Vasileios Antoniadis
Summary: This study investigates the effects of different amendments and low-molecular-weight organic acids on the release of potentially toxic elements (PTEs) from soils. The highest release of PTEs was observed with citric acid, followed by oxalic and malic acids. The addition of poultry manure was found to be the most environmentally friendly amendment. The results highlight the importance of considering cadmium (Cd) in order to prevent environmental pollution.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Polymer Science
Lorenzo Bonetti, Andrea Fiorati, Agnese D'Agostino, Carlo Maria Pelacani, Roberto Chiesa, Silvia Fare, Luigi De Nardo
Summary: This study introduces a novel MC-based hydrogel for the pH-triggered release of AgNPs in infected wounds. Physicochemical and rheological properties of MC hydrogels were optimized, defining the optimal conditions for crosslinking. MC/AgNPs nanocomposite hydrogels were obtained via an in situ synthesis process using MC as both a capping and reducing agent.
Article
Food Science & Technology
Qijia Zhou, Zhiping Zhang, Yiqun Huang, Lihong Niu, Junjian Miao, Keqiang Lai
Summary: This study evaluated the effects of lactic acid, citric acid, and malic acid on the rheological properties of fish gelatin obtained from tilapia skin. The addition of these acids weakened the gel strength and rheological properties, with higher concentrations having a more significant effect. Lactic acid had a lesser effect compared to citric acid and malic acid, which was consistent with their effects on pH.
Article
Construction & Building Technology
Sabrina Gerger, Andre Baldermann, Martin Dietzel
Summary: Consolidation of MgO castables by organic acids is a common technique for various applications, but the distinct hardening mechanisms of caste stone formation are still poorly constrained. In this study, the individual hardening behavior was experimentally investigated by intermixing of different components and organic additives, showing that MgO purity, reactivity, and the type of organic additive all play significant roles in the evolution of hardening and the formation of Mgorgano salt. MgO with higher reactivity and certain organic additives result in stronger hardening, while low purity MgO_D can also yield in stronger hardening due to the presence of additional binder phases.
CASE STUDIES IN CONSTRUCTION MATERIALS
(2021)
Article
Multidisciplinary Sciences
Nasser Mohammed Hosny, Islam Gomaa, Maryam G. Elmahgary, Medhat A. Ibrahim
Summary: Carbon doped ZnO nanoparticles were synthesized and characterized in this study. The results showed that the synthesized ZnO nanoparticles had a hexagonal 2D structure with a layer thickness of 25 nm and an optical band gap of 2.9 eV. Under UV irradiation, the ZnO nanoparticles exhibited excellent photocatalytic degradation performance towards both anionic and cationic dyes.
SCIENTIFIC REPORTS
(2023)
Article
Environmental Sciences
Yonghong Zheng, Jiangwei Lu, Zhiguo Zhang, Yating Li, Yuning Tan, Weiqing Cai, Chengnan Ma, Fangling Chen
Summary: This study investigated the effects of low molecular weight organic acids (citric acid and malic acid) on the migration properties of nickel in soil. The results showed that increasing concentrations of citric acid and malic acid can promote the migration of nickel in soil, and the activation effect of organic acids on nickel weakens over time.
Article
Agriculture, Multidisciplinary
Dongfeng Jia, Ziyi Xu, Lu Chen, Qing Huang, Chunhui Huang, Junjie Tao, Xueyan Qu, Xiaobiao Xu
Summary: The levels of citric acid and malic acid in the fruit of the new kiwifruit cultivar A. eriantha 'Ganlv 1' increased during fruit development, while quinic acid content decreased. The high accumulation of citric acid was attributed to increased activity of citrate synthase and decreased activities of two degradation-related enzymes. The accumulation of malic acid was mainly influenced by the synthesis catalyzed by NAD-dependent malate dehydrogenase and phosphoenolpyruvate carboxylase. These findings enhance our understanding of fruit acidity quality formation.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Horticulture
Shariq Mahmood Alam, Dong-Hai Liu, Yong-Zhong Liu, Han Han, Syed Bilal Hussain, Muhammad Ateeq
Summary: This study identified significant differences in organic acid profiles between top-canopy and bottom-canopy fruits, with the latter showing higher citrate content and lower malate content. The transcript levels of genes related to organic acid metabolism were also found to be different between the two canopy positions, likely due to microclimate changes impacting gene expression.
SCIENTIA HORTICULTURAE
(2022)
Article
Chemistry, Multidisciplinary
Pan Wang, Bingqin Li, Baiyue Li, Jing Yang, Xingran Xu, Shang-Tian Yang, Xiang Zou
Summary: This study investigated the carbon-economic biosynthesis of poly-2-hydrobutanedioic acid (P2HBD) from ethanol as the sole carbon source. The results showed that ethanol could be efficiently converted into P2HBD via a biosynthetic mechanism. A modular assembly strategy was designed to balance ethanol oxidation, glyoxylic acid shunt, and the gluconeogenesis pathway, and promoter engineering was used for precise regulation. An adaptive evolution strategy was performed to enhance ethanol tolerance, resulting in a mutant strain with comparable yields. These findings provide new insights into carbon-economic transformation from ethanol substrates into biopolymers and chemicals.
Review
Biochemistry & Molecular Biology
Dirk Roosterman, Graeme Stuart Cottrell
Summary: The Citric Acid Cycle, initially proposed in 1937 by Sir H. A Krebs, is a unidirectional cycle crucial for the degradation of lactic acid and energy production. The heart lactate dehydrogenase center · proton-linked monocarboxylate transporter 1 complex plays a key role in catalyzing the initial step of the cycle by oxidizing lactate to pyruvate. By incorporating oxaloacetic acid into the cycle, anabolic processes can be integrated, allowing organisms to recover ATP more efficiently.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Materials Science, Multidisciplinary
Jian-Zhi Wang, Yi-Chin Tang, Yun-Hwei Shen
Summary: The Taguchi method was used to investigate the leaching of SmCo magnet waste with citric acid and malic acid. Factor effect analysis of experimental results was conducted to understand the influence of temperature, acid concentration, solid-to-liquid ratio, time, and hydrogen peroxide on leaching efficiency. Optimal leaching parameters were obtained through confirmation experiments.
Article
Chemistry, Multidisciplinary
Yonghong Zheng, Yating Li, Zhiguo Zhang, Yuning Tan, Weiqing Cai, Chengnan Ma, Fangling Chen, Jiangwei Lu
Summary: This study explored the impact of low-molecular-weight organic acids (citric acid and malic acid) on the migration characteristics of Pb in contaminated soils. The results showed that the addition of these organic acids improved the activity of Pb in the soil and increased the fraction of exchangeable Pb. The activation effect of citric acid was found to be greater than that of malic acid. However, over time, the activation effect of organic acids on Pb weakened, with a transformation from loosely bound Pb to strongly bound Pb.
FRONTIERS IN CHEMISTRY
(2022)
Article
Engineering, Chemical
Shokrullah Hussaini, Sait Kursunoglu, Soner Top, Zela Tanlega Ichlas, Muammer Kaya
Summary: The study investigated the recovery of zinc from flotation tailing using 17 different leaching agents. Results showed that sulfuric acid and citric acid exhibited high selectivity and efficiency in zinc dissolution. Sodium hydroxide was found to achieve simultaneous dissolution of zinc and lead effectively.
MINERALS ENGINEERING
(2021)
Article
Agriculture, Dairy & Animal Science
Qixian Feng, Wenjiao Shi, Siqi Chen, Abraham Allan Degen, Yue Qi, Fulin Yang, Jing Zhou
Summary: The addition of malic acid, citric acid, and Lactobacillus acidophilus (L) combined with an organic acid can improve the quality of Chamaecrista rotundifolia silage and increase the relative abundance of beneficial bacteria.
Article
Environmental Sciences
Mohsen Beygi, Mohsen Jalali, Jianxu Wang
Summary: The presence of organic acids in the soil can reduce the adsorption capacity of stabilizers used in contaminated soil remediation. The addition of aluminum oxide and titanium dioxide nanoparticles at a rate of 2% enhances the adsorption of Cd, Cu, Ni, and Zn. This study highlights the importance of studying the interactions between organic and potentially toxic elements in agricultural soils amended with nanoparticles.
JOURNAL OF SOILS AND SEDIMENTS
(2023)
Article
Chemistry, Physical
Monika Haponska, Paulina Modrakowska, Karolina Balik, Anna Bajek, Anne Coloigner, Bartosz Tylkowski, Marta Giamberini
Summary: The focus of the research was on preparing and characterizing novel plasters based on Carboxymethyl Chitosan derivative for treating radiation dermatitis with extracted Biologic Active Compounds. The optimized 2La sample showed promising results in terms of flexibility, released BACs, and promoting keratinocyte proliferation and viability.
Article
Biochemistry & Molecular Biology
Michal Zabiszak, Justyna Frymark, Martyna Nowak, Jakub Grajewski, Klaudia Stachowiak, Malgorzata T. Kaczmarek, Renata Jastrzab
Summary: In this study, binary complexes of alpha-hydroxy acids with d-electron metal ions were investigated using potentiometric measurements and spectroscopic methods. The results showed that dimers were formed with copper(II) ions, while monomers were formed with cobalt(II) and nickel(II) ions.
Article
Chemistry, Inorganic & Nuclear
Malgorzata T. Kaczmarek, Joanna Strzelec, Maciej Kubicki, Jozef Kovac, Renata Jastrzab
Summary: This article explores the template condensation reactions of 5-methylsalicylaldehyde with 4,5-dimethyl1,2-phenylenediamine in the presence of copper(II) ion and selected lanthanide(III) ions, resulting in the synthesis of two new Salen-type Schiff base complexes. Characterization and identification of these complexes were conducted using spectroscopic methods and elemental analysis.
Article
Chemistry, Physical
Malwina Gabryel-Skrodzka, Martyna Nowak, Klaudia Stachowiak, Michal Zabiszak, Kazuma Ogawa, Renata Jastrzab
Summary: The influence of pH on the complex formation of phosphoethanolamine and pyrimidine nucleosides with copper(II) ions was studied using potentiometric and spectroscopic methods. Data on stability constants and equilibrium constants were obtained, confirming the involvement of phosphate groups and the influence of pH on coordination mode. These studied complexes will be potentially applied as biomaterials with biological applications.
Review
Chemistry, Multidisciplinary
Maciej Staszak, Katarzyna Staszak, Karolina Wieszczycka, Anna Bajek, Krzysztof Roszkowski, Bartosz Tylkowski
Summary: The paper provides a comprehensive overview of the use of artificial intelligence systems, particularly neural networks, in drug design to identify chemical structures with medical relevance. Successful training of neural networks requires a large set of training data related to the chemical structure-biological activity relationship, which can be obtained from experimental measurements or appropriate quantum models. Recent advancements in computing power have led to rapid development in neural network systems and a growing interest in deep learning techniques, allowing for a new level of abstraction in network modeling.
WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE
(2022)
Article
Engineering, Environmental
Katarzyna Burdzy, Andreas Aurich, Steffi Hunger, Renata Jastrazab, Michal Zabiszak, Dorota Kolodynska
Summary: In this study, the effects of citric acid as a biodegradable complexing agent on the sorption process of La(III), Nd(III), and Ho(III) ions were investigated. The adsorption capacity was analyzed by considering factors such as pH, molar ratio, contact time, initial concentrations, and temperature. The results showed that the Purolite S957 chelating ion exchanger had the highest adsorption capacity. The study also evaluated the reusability of ion exchangers and simulated the behavior of fixed bed columns using dynamic experiments.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Materials Science, Multidisciplinary
M. Nowak, A. Tolinska, L. Marciniak, M. Skrobanska, B. Tylkowski, M. Frankowski, M. T. Kaczmarek, R. Jastrzab
Summary: This study synthesized silver nanoparticles using D-glucose reduction and evaluated their characteristics. The results showed that D-glucose-reduced silver nanoparticles possessed excellent antibacterial properties, making them suitable for daily soap production.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Multidisciplinary Sciences
Nurmaya Effendi, Kenji Mishiro, Hiroshi Wakabayashi, Malwina Gabryel-Skrodzka, Kazuhiro Shiba, Junichi Taki, Renata Jastrzab, Seigo Kinuya, Kazuma Ogawa
Summary: Radiolabeled long-chain fatty acids are important imaging agents for diagnosing metabolic heart dysfunction. Four radiogallium-labeled fatty acid tracers were synthesized and evaluated for myocardial metabolic imaging, showing the need for further structural modifications to increase uptake in the heart.
Article
Biochemistry & Molecular Biology
Bartosz Tylkowski, Piotr Konopka, Malgorzata Maj, Lukasz Kazmierski, Monika Skrobanska, Xavier Montane, Marta Giamberini, Anna Bajek, Renata Jastrzab
Summary: According to the American Cancer Society, there have been approximately 54,000 new cases of oral cavity or oropharyngeal cancers in the United States in 2021, resulting in about 10,850 deaths. Traditional cancer management therapies such as surgery and radio- and chemotherapy can cause damage to surrounding tissues, highlighting the need for non-surgical treatments for oral cavities. Research has shown that biologically active compounds extracted from European Spruce needles, particularly luteolin, have potential anti-tumorigenic properties against squamous cell carcinoma. These compounds show promise as materials for oral health applications due to their high selectivity, robustness, and non-toxicity.
Article
Chemistry, Inorganic & Nuclear
Monika Skrobanska, Michal Zabiszak, Katarzyna Taras-Goslinska, Martyna Nowak, Malgorzata T. Kaczmarek, Justyna Frymark, Danuta Michalska, Renata Jastrzab
Summary: This study investigated the new complexes formed by 6-methyl-2-thiouracil and copper ions. Hydroxo complexes were detected for the first time, and the influence of the metal ion: ligand concentration ratio on the distribution of forms and fluorescent properties was demonstrated. The overall stability constants of the complexes were calculated, and the coordination type in the studied system was determined.
Article
Biochemistry & Molecular Biology
Malwina Gabryel-Skrodzka, Martyna Nowak, Anna Teubert, Renata Jastrzab
Summary: The activity of phosphate groups of phosphoethanolamine and pyrimidine nucleotides in the process of complexation metal ions in aqueous solution was studied. The results showed that at lower pH, copper(II) ions are only complexed by phosphate groups, while the endocyclic nitrogen atom of nucleotides interacts with the -NH3+ groups of phosphoethanolamine.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Chemistry, Inorganic & Nuclear
Marta J. Woznlak Budych, Katarzyna Staszak, Anna Bajek, Filip Pniewski, Renata Jastrzab, Maciej Staszak, Bartosz Tylkowski, Karolina Wieszczycka
Summary: This paper summarizes the most interesting applications of polyoxometalates (POMs) in the past five years, highlighting the relationship between their complex nature, properties, and chemical structure. POMs are a well-known class of metal-oxygen nanoclusters with adjustable size and structure. Due to their diverse properties, they have received great attention in various fields of current socioeconomic interest, including materials science, catalysis, hydrogen production, environmental protection, and advanced medicine. The role of the characteristic structure of this class of compounds in the discussed applications has been emphasized.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Multidisciplinary Sciences
Malwina Gabryel-Skrodzka, Martyna Nowak, Jakub Grajewski, Renata Jastrzab
Summary: The complexation reactions of phosphocholine, pyrimidine nucleosides, and nucleotides with copper(II) ions were investigated. The stability constants of the species were determined using potentiometric methods and computer calculations. Spectroscopic methods were used to establish the coordination mode of the complexes formed in the pH range of 2.5-11.0. These studies provide insights into the role of copper(II) ions in living organisms and the interactions with the studied bioligands. The impact of phosphate groups on metal ion complexation and ligand interactions was also discussed.
SCIENTIFIC REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Nur Izni Ramzi, Kenji Mishiro, Masayuki Munekane, Takeshi Fuchigami, Xiaojun Hu, Renata Jastrzab, Yoji Kitamura, Seigo Kinuya, Kazuma Ogawa
Summary: Radioiodinated porphyrin derivatives and their corresponding nonradioactive iodine introduced compounds were synthesized and evaluated for their cancer theranostic potential. The iodinated porphyrin derivatives [I-123/nat]3 and [I-123/nat]9 exhibited significant cytotoxicity and high retention in tumors, making them promising candidates for cancer treatment and molecular imaging.
RSC MEDICINAL CHEMISTRY
(2022)
