4.5 Article

Prevalence and correlates of fatigue and its association with quality of life among clinically stable older psychiatric patients during the COVID-19 outbreak: a cross-sectional study

Journal

GLOBALIZATION AND HEALTH
Volume 16, Issue 1, Pages -

Publisher

BMC
DOI: 10.1186/s12992-020-00644-6

Keywords

Fatigue; Quality of life; Older psychiatric patients; COVID-19

Funding

  1. National Science and Technology Major Project for investigational new drug [2018ZX09201-014]
  2. Beijing Municipal Science & Technology Commission [Z181100001518005]
  3. University of Macau [MYRG2019-00066-FHS]
  4. Key Diagnosis and treatment Program of Suzhou [LCZX201615]

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Background The pattern of fatigue in older psychiatric patients during the COVID-19 outbreak was unknown. This study examined the prevalence of fatigue and its association with overall quality of life (overall QOL) in clinically stable older patients with psychiatric disorders during the COVID-19 outbreak. Methods This was a multicenter, cross-sectional study. Fatigue, depressive symptoms, pain, insomnia symptoms, and overall QOL were assessed with standardized instruments. Results A total of 1063 patients were recruited. The prevalence of fatigue was 47.1% (95%CI: 44.1-50.1%). An analysis of covariance revealed that overall QOL was significantly lower in patients with fatigue compared to those without (P = 0.011). A multiple logistic regression analysis revealed that more severe depressive symptoms (OR = 1.15, P < 0.001), insomnia symptoms (OR = 1.08, P < 0.001) and pain (OR = 1.43, P < 0.001) were significantly associated with fatigue. Conclusions Fatigue is common among clinically stable older patients with psychiatric disorders during the COVID-19 outbreak. Considering its negative impact on overall QOL, regular assessment of fatigue and appropriate treatment warrant attention in this subpopulation.

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