Downregulated exosomal microRNA-148b-3p in cancer associated fibroblasts enhance chemosensitivity of bladder cancer cells by downregulating the Wnt/β-catenin pathway and upregulating PTEN

A novel nanoformulation of PLGA with high non-ionic surfactant content improves in vitro and in vivo PTX activity against lung cancer

(2019) Julia Jiménez-López et al.   PHARMACOLOGICAL RESEARCH

Gemcitabine combined with docetaxel precisely regressed a recurrent leiomyosarcoma peritoneal metastasis in a patient-derived orthotopic xenograft (PDOX) model

(2019) Kentaro Miyake et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Jarid2 enhances the progression of bladder cancer through regulating PTEN/AKT signaling

(2019) Xuliang Wang et al.   LIFE SCIENCES

CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer

(2019) J. L. Hu et al.   Molecular Cancer

MicroRNA-130b targets PTEN to induce resistance to cisplatin in lung cancer cells by activating Wnt/β-catenin pathway

(2018) Qiang Zhang et al.   CELL BIOCHEMISTRY AND FUNCTION

SPIN1, negatively regulated by miR-148/152, enhances Adriamycin resistance via upregulating drug metabolizing enzymes and transporter in breast cancer

(2018) Xu Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications

(2018) Vignesh Sundararajan et al.   CELLULAR ONCOLOGY

Mutual concessions and compromises between stromal cells and cancer cells: driving tumor development and drug resistance

(2018) Pritish Nilendu et al.   CELLULAR ONCOLOGY

Three-dimensional organoid culture reveals involvement of Wnt/β-catenin pathway in proliferation of bladder cancer cells

(2018) Takahiro Yoshida et al.   Oncotarget

microRNA profiles in urine by next-generation sequencing can stratify bladder cancer subtypes

(2018) Barbara Pardini et al.   Oncotarget

Differential distribution and enrichment of non-coding RNAs in exosomes from normal and Cancer-associated fibroblasts in colorectal cancer

(2018) Mercedes Herrera et al.   Molecular Cancer

Combination chemotherapy with Zyflamend reduced the acquired resistance of bladder cancer cells to cisplatin through inhibiting NFκB signaling pathway

(2018) Yanshi Xue et al.   OncoTargets and Therapy

Bladder Cancer Incidence and Mortality: A Global Overview and Recent Trends

(2017) Sebastien Antoni et al.   EUROPEAN UROLOGY

Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblasts

(2017) Fengming Yang et al.   Molecular Cancer

Exosomes containing differential expression of microRNA and mRNA in osteosarcoma that can predict response to chemotherapy

(2017) Ji-Feng Xu et al.   Oncotarget

CUL4B promotes bladder cancer metastasis and induces epithelial-to-mesenchymal transition by activating the Wnt/β-catenin signaling pathway

(2017) Xia-Wa Mao et al.   Oncotarget

Refinement of intraperitoneal injection of sodium pentobarbital for euthanasia in laboratory rats (Rattus norvegicus)

(2016) Katie K Zatroch et al.   BMC Veterinary Research

Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition

(2015) Tong-Hong Wang et al.   Oncotarget

Up-regulation of human cervical cancer proto-oncogene contributes to hepatitis B virus-induced malignant transformation of hepatocyte by down-regulating E-cadherin

(2015) Junfeng Li et al.   Oncotarget

Circulating miR-148b and miR-133a as biomarkers for breast cancer detection

(2015) Jie Shen et al.   Oncotarget

Serum microRNA expression signatures identified from genome-wide microRNA profiling serve as novel noninvasive biomarkers for diagnosis and recurrence of bladder cancer

(2014) Xiumei Jiang et al.   INTERNATIONAL JOURNAL OF CANCER

Exosomes

(2013) Huang-Ge Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

PTEN deficiency is associated with reduced sensitivity to mTOR inhibitor in human bladder cancer through the unhampered feedback loop driving PI3K/Akt activation

(2013) E Seront et al.   BRITISH JOURNAL OF CANCER

Bladder cancer cell-derived exosomes inhibit tumor cell apoptosis and induce cell proliferation in vitro

(2013) LIN YANG et al.   Molecular Medicine Reports

Gastric Cancer Exosomes Trigger Differentiation of Umbilical Cord Derived Mesenchymal Stem Cells to Carcinoma-Associated Fibroblasts through TGF-β/Smad Pathway

(2012) Jianmei Gu et al.   PLoS One

Bladder Cancer: Current Management and Opportunities for a Personalized Approach

(2010) Matthew D. Galsky et al.   MOUNT SINAI JOURNAL OF MEDICINE

β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation

(2010) I Ahmad et al.   ONCOGENE

Inactivation of p53 and Pten promotes invasive bladder cancer

(2009) A. M. Puzio-Kuter et al.   GENES & DEVELOPMENT