Estimating cell-type-specific DNA methylation effects in heterogeneous cellular populations

eFORGE v2.0: updated analysis of cell type-specific signal in epigenomic data

(2019) Charles E Breeze et al.   BIOINFORMATICS

Cell-type-specific resolution epigenetics without the need for cell sorting or single-cell biology

(2019) Elior Rahmani et al.   Nature Communications

The “All of Us” Research Program

(2019)   NEW ENGLAND JOURNAL OF MEDICINE

Circulating Progenitor Cells and Racial Differences: A Possible Contribution to Health Disparity

(2018) Ayman S Samman-Tahhan et al.   CIRCULATION RESEARCH

Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures

(2017) Joshua M Galanter et al.   eLife

Reference-free deconvolution of DNA methylation data and mediation by cell composition effects

(2016) E. Andres Houseman et al.   BMC BIOINFORMATICS

Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective

(2015) E Andres Houseman et al.   BMC BIOINFORMATICS

An epigenome-wide association study of total serum immunoglobulin E concentration

(2015) Liming Liang et al.   NATURE

Reference-free cell mixture adjustments in analysis of DNA methylation data

(2014) Eugene Andres Houseman et al.   BIOINFORMATICS

DNA methylation and body-mass index: a genome-wide analysis

(2014) Katherine J Dick et al.   LANCET

Epigenome-wide association studies without the need for cell-type composition

(2014) James Zou et al.   NATURE METHODS

Accounting for cellular heterogeneity is critical in epigenome-wide association studies

(2014) Andrew E Jaffe et al.   GENOME BIOLOGY

Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

(2013) Yun Liu et al.   NATURE BIOTECHNOLOGY

Measuring cell-type specific differential methylation in human brain tissue

(2013) Carolina M Montaño et al.   GENOME BIOLOGY

Health Disparities in Asthma

(2012) Erick Forno et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

DNA methylation arrays as surrogate measures of cell mixture distribution

(2012) Eugene Houseman et al.   BMC BIOINFORMATICS

Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking

(2012) Natalie S. Shenker et al.   HUMAN MOLECULAR GENETICS

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

(2012) Lovisa E. Reinius et al.   PLoS One

Heterogeneity in White Blood Cells Has Potential to Confound DNA Methylation Measurements

(2012) Bjorn T. Adalsteinsson et al.   PLoS One

Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies

(2011) Andrew E. Teschendorff et al.   BIOINFORMATICS

Racial differences in gene-specific DNA methylation levels are present at birth

(2011) Ronald M. Adkins et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated

(2010) Mun-Kit Choy et al.   BMC GENOMICS

Environmental epigenetics

(2010) V Bollati et al.   HEREDITY

Epigenetics and environmental chemicals

(2009) Andrea Baccarelli et al.   CURRENT OPINION IN PEDIATRICS