MicroRNA-1252-5p Associated with Extracellular Vesicles Enhances Bortezomib Sensitivity in Multiple Myeloma Cells by Targeting Heparanase

MicroRNAs-Based Nano-Strategies as New Therapeutic Approach in Multiple Myeloma to Overcome Disease Progression and Drug Resistance

(2020) Vanessa Desantis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Diagnostic and Therapeutic Potential of Extracellular Vesicles in B-Cell Malignancies

(2020) Ernesto Gargiulo et al.   Frontiers in Oncology

Improved loading of plasma derived-extracellular vesicles to encapsulate antitumor miRNAs

(2019) Margherita Alba Carlotta Pomatto et al.   Molecular Therapy-Methods & Clinical Development

Downregulation of DCC sensitizes multiple myeloma cells to bortezomib treatment

(2019) Dorival Rodrigues‑Junior et al.   Molecular Medicine Reports

miR-520g and miR-520h overcome bortezomib resistance in multiple myeloma via suppressing APE1

(2019) Xiaoli Yuan et al.   CELL CYCLE

Tumor‑suppressive miR‑299‑3p inhibits gastric cancer cell invasion by targeting heparanase

(2019) Xiangjun Zhou et al.   Molecular Medicine Reports

The emerging role of exosomes in multiple myeloma

(2019) Milad Moloudizargari et al.   BLOOD REVIEWS

Circulating extracellular vesicle-associated TGFβ3 modulates response to cytotoxic therapy in head and neck squamous cell carcinoma

(2019) Dorival Mendes Rodrigues-Junior et al.   CARCINOGENESIS

Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior

(2018) Shyam K. Bandari et al.   MATRIX BIOLOGY

Efficient RNA drug delivery using red blood cell extracellular vesicles

(2018) Waqas Muhammad Usman et al.   Nature Communications

MicroRNA-497 inhibits multiple myeloma growth and increases susceptibility to bortezomib by targeting Bcl-2

(2018) Faqing Tian et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

CircABCB10 promotes nonsmall cell lung cancer cell proliferation and migration by regulating the miR-1252/FOXR2 axis

(2018) Xufeng Tian et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Role of tumor suppressor p53 and micro-RNA interplay in multiple myeloma pathogenesis

(2017) Jahangir Abdi et al.   Journal of Hematology & Oncology

MicroRNA-429 decreases the invasion ability of gastric cancer cell line BGC-823 by downregulating the expression of heparanase

(2017) Nan Sheng et al.   Experimental and Therapeutic Medicine

MicroRNA-1258: An invasion and metastasis regulator that targets heparanase in gastric cancer

(2017) Jinxin Shi et al.   Oncology Letters

Evaluation of electroporation-induced adverse effects on adipose-derived stem cell exosomes

(2016) Kasper Bendix Johnsen et al.   CYTOTECHNOLOGY

Chemotherapy induces expression and release of heparanase leading to changes associated with an aggressive tumor phenotype

(2016) Vishnu C. Ramani et al.   MATRIX BIOLOGY

The delivery of therapeutic oligonucleotides

(2016) Rudolph L. Juliano   NUCLEIC ACIDS RESEARCH

miR-20b reduces 5-FU resistance by suppressing the ADAM9/EGFR signaling pathway in colon cancer

(2016) Qiang Fu et al.   ONCOLOGY REPORTS

Multiple myeloma

(2015) Christoph Röllig et al.   LANCET

DIANA-miRPath v3.0: deciphering microRNA function with experimental support

(2015) Ioannis S. Vlachos et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-20b inhibits the proliferation, migration and invasion of bladder cancer EJ cells via the targeting of cell cycle regulation and Sp-1-mediated MMP-2 expression

(2015) SUNG LYEA PARK et al.   ONCOLOGY REPORTS

Targeting heparanase overcomes chemoresistance and diminishes relapse in myeloma

(2015) Vishnu C. Ramani et al.   Oncotarget

The impact of recent chemotherapy innovation on the longevity of myeloma patients: US and international evidence

(2015) Gisela Hostenkamp et al.   SOCIAL SCIENCE & MEDICINE

Bortezomib for the treatment of multiple myeloma

(2014) Sebastian Grosicki et al.   Expert Review of Hematology

The expression and clinical significance of microRNA-1258 and heparanase in human breast cancer

(2013) Dabei Tang et al.   CLINICAL BIOCHEMISTRY

Lentiviral miR30-based RNA Interference against Heparanase Suppresses Melanoma Metastasis with Lower Liver and Lung Toxicity

(2013) Xiao-yan Liu et al.   International Journal of Biological Sciences

MicroRNA theragnostics for the clinical management of multiple myeloma

(2013) N Ahmad et al.   LEUKEMIA

Recent improvement in survival of patients with multiple myeloma: variation by ethnicity

(2013) Dianne Pulte et al.   LEUKEMIA & LYMPHOMA

Novel Generation of Agents With Proven Clinical Activity in Multiple Myeloma

(2013) María-Victoria Mateos et al.   SEMINARS IN ONCOLOGY

Proteasome inhibitors in multiple myeloma: 10 years later

(2012) P. Moreau et al.   BLOOD

Exosome-mediated delivery of siRNA in vitro and in vivo

(2012) Samir El-Andaloussi et al.   Nature Protocols

MicroRNA-1258 Suppresses Breast Cancer Brain Metastasis by Targeting Heparanase

(2011) L. Zhang et al.   CANCER RESEARCH

SST0001, a Chemically Modified Heparin, Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase/Syndecan-1 Axis

(2011) Joseph P. Ritchie et al.   CLINICAL CANCER RESEARCH

Multiple Myeloma

(2011) Antonio Palumbo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Development of an enzyme-linked immunosorbent assay (ELISA)-like fluorescence assay to investigate the interactions of glycosaminoglycans to cells

(2008) Rodrigo Ippolito Bouças et al.   ANALYTICA CHIMICA ACTA

Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma

(2008) R A Kyle et al.   LEUKEMIA