Intercellular Communication in the Nervous System Goes Viral

The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles

(2020) Andrew M. Leidal et al.   NATURE CELL BIOLOGY

Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins

(2020) Simon Erlendsson et al.   NATURE NEUROSCIENCE

Memory engrams: Recalling the past and imagining the future

(2020) Sheena A. Josselyn et al.   SCIENCE

Experience-Dependent Development and Maintenance of Binocular Neurons in the Mouse Visual Cortex

(2020) Kyle R. Jenks et al.   Cell Reports

Structure of Drosophila melanogaster ARC1 reveals a repurposed molecule with characteristics of retroviral Gag

(2020) Matthew A. Cottee et al.   Science Advances

Autophagy coupled to translation is required for long-term memory

(2020) Kiran Pandey et al.   Autophagy

A retrotransposon gag-like-3 gene RTL3 and SOX-9 co-regulate the expression of COL2A1 in chondrocytes

(2020) Hope C. Ball et al.   CONNECTIVE TISSUE RESEARCH

Extracellular Vesicles in the Pathogenesis of Viral Infections in Humans

(2020) Allen Caobi et al.   Viruses-Basel

Arc self‐association and formation of virus‐like capsids are mediated by an N‐terminal helical coil motif

(2020) Maria S. Eriksen et al.   FEBS Journal

Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation

(2019) Wenchi Zhang et al.   MOLECULAR CELL

Origins and evolutionary consequences of ancient endogenous retroviruses

(2019) Welkin E. Johnson   NATURE REVIEWS MICROBIOLOGY

The Capsid Domain of Arc Changes Its Oligomerization Propensity through Direct Interaction with the NMDA Receptor

(2019) Lau Dalby Nielsen et al.   STRUCTURE

The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification

(2019) Mona Abed et al.   PLoS One

The neural circuit linking mushroom body parallel circuits induces memory consolidation in Drosophila

(2019) Hiroko Awata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diseases of the nERVous system: retrotransposon activity in neurodegenerative disease

(2019) Oliver H. Tam et al.   Mobile DNA

Endogenous retroviruses are associated with hippocampus-based memory impairment

(2019) Roman Sankowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer

(2018) Elissa D. Pastuzyn et al.   CELL

Retrovirus-like Gag Protein Arc1 Binds RNA and Traffics across Synaptic Boutons

(2018) James Ashley et al.   CELL

PNMA family: Protein interaction network and cell signalling pathways implicated in cancer and apoptosis

(2018) Siew Wai Pang et al.   CELLULAR SIGNALLING

Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities

(2018) Erik I. Hallin et al.   JOURNAL OF NEUROCHEMISTRY

Locally coordinated synaptic plasticity of visual cortex neurons in vivo

(2018) Sami El-Boustani et al.   SCIENCE

Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes

(2018) Qiang Cai et al.   SCIENCE

The mechanistic link between Arc/Arg3.1 expression and AMPA receptor endocytosis

(2018) Mark J. Wall et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Arc protein: a flexible hub for synaptic plasticity and cognition

(2018) Oleksii Nikolaienko et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Human Endogenous Retroviruses in Neurological Diseases

(2018) Patrick Küry et al.   TRENDS IN MOLECULAR MEDICINE

Tau Activates Transposable Elements in Alzheimer’s Disease

(2018) Caiwei Guo et al.   Cell Reports

PEG10 as an oncogene: expression regulatory mechanisms and role in tumor progression

(2018) Tian Xie et al.   Cancer Cell International

PEG10 counteracts signaling pathways of TGF-β and BMP to regulate growth, motility and invasion of SW1353 chondrosarcoma cells

(2018) Yuhei Yahiro et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Activity-Regulated Transcription: Bridging the Gap between Neural Activity and Behavior

(2018) Ee-Lynn Yap et al.   NEURON

A role for autophagy in long-term spatial memory formation in male rodents

(2017) Michael J. Hylin et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Arc restores juvenile plasticity in adult mouse visual cortex

(2017) Kyle R. Jenks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A comparative analysis of the foamy and ortho virus capsid structures reveals an ancient domain duplication

(2017) William R. Taylor et al.   BMC STRUCTURAL BIOLOGY

Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence

(2017) Esperanza Fernández et al.   Cell Reports

Dissection of specific binding of HIV-1 Gag to the 'packaging signal' in viral RNA

(2017) Mauricio Comas-Garcia et al.   eLife

Regulatory activities of transposable elements: from conflicts to benefits

(2016) Edward B. Chuong et al.   NATURE REVIEWS GENETICS

Extracellular vesicles in neurodegenerative disease — pathogenesis to biomarkers

(2016) Alexander G. Thompson et al.   Nature Reviews Neurology

Extracellular vesicles round off communication in the nervous system

(2016) Vivian Budnik et al.   NATURE REVIEWS NEUROSCIENCE

Host RNA Packaging by Retroviruses: A Newly Synthesized Story

(2016) Matthew J. Eckwahl et al.   mBio

Genetic Disruption of Arc/Arg3.1 in Mice Causes Alterations in Dopamine and Neurobehavioral Phenotypes Related to Schizophrenia

(2016) Francesca Managò et al.   Cell Reports

Coordination between Drosophila Arc1 and a specific population of brain neurons regulates organismal fat

(2015) Jeremy Mosher et al.   DEVELOPMENTAL BIOLOGY

LDOC1 inhibits proliferation and promotes apoptosis by repressing NF-κB activation in papillary thyroid carcinoma

(2015) Shuiying Zhao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

ATG12–ATG3 interacts with Alix to promote basal autophagic flux and late endosome function

(2015) Lyndsay Murrow et al.   NATURE CELL BIOLOGY

Structural Basis of Arc Binding to Synaptic Proteins: Implications for Cognitive Disease

(2015) Wenchi Zhang et al.   NEURON

Retroviral envelope gene captures andsyncytinexaptation for placentation in marsupials

(2015) Guillaume Cornelis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular vesicles – Their role in the packaging and spread of misfolded proteins associated with neurodegenerative diseases

(2015) Bradley M. Coleman et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

HIV-1 Replication and the Cellular Eukaryotic Translation Apparatus

(2015) Santiago Guerrero et al.   Viruses-Basel

Cognitive Function Related to the Sirh11/Zcchc16 Gene Acquired from an LTR Retrotransposon in Eutherians

(2015) Masahito Irie et al.   PLoS Genetics

Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes

(2015) Oswald Steward et al.   Frontiers in Molecular Neuroscience

Unmasking immune sensing of retroviruses: Interplay between innate sensors and host effectors

(2014) Nadine van Montfoort et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Sirh7/Ldoc1 knockout mice exhibit placental P4 overproduction and delayed parturition

(2014) M. Naruse et al.   DEVELOPMENT

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

(2014) Zandrea Ambrose et al.   VIROLOGY

How HIV-1 Gag assembles in cells: Putting together pieces of the puzzle

(2014) Jaisri R. Lingappa et al.   VIRUS RESEARCH

Turning gold into ‘junk’: transposable elements utilize central proteins of cellular networks

(2013) György Abrusán et al.   NUCLEIC ACIDS RESEARCH

HIV: Cell Binding and Entry

(2013) C. B. Wilen et al.   Cold Spring Harbor Perspectives in Medicine

A virocentric perspective on the evolution of life

(2013) Eugene V Koonin et al.   Current Opinion in Virology

Caspase activation regulates the extracellular export of autophagic vacuoles

(2012) Isabelle Sirois et al.   Autophagy

Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ

(2012) Hiroyuki Okuno et al.   CELL

The role of genes domesticated from LTR retrotransposons and retroviruses in mammals

(2012) Tomoko Kaneko-Ishino et al.   Frontiers in Microbiology

Arc/Arg3.1 Regulates an Endosomal Pathway Essential for Activity-Dependent β-Amyloid Generation

(2011) Jing Wu et al.   CELL

New views of Arc, a master regulator of synaptic plasticity

(2011) Jason D Shepherd et al.   NATURE NEUROSCIENCE

Multivesicular bodies in neurons: Distribution, protein content, and trafficking functions

(2011) Christopher S. Von Bartheld et al.   PROGRESS IN NEUROBIOLOGY

Loss of Arc renders the visual cortex impervious to the effects of sensory experience or deprivation

(2010) Cortina L McCurry et al.   NATURE NEUROSCIENCE

Mef2-mediated transcription of the miR379–410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels

(2009) Roberto Fiore et al.   EMBO JOURNAL

Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta

(2008) Yoichi Sekita et al.   NATURE GENETICS

Cellular proteins detected in HIV-1

(2008) David E. Ott   REVIEWS IN MEDICAL VIROLOGY

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE