Partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids

Use of human liver and EpiSkin™ S9 subcellular fractions as a screening assays to compare the in vitro hepatic and dermal metabolism of 47 cosmetics‐relevant chemicals

(2020) Joan Eilstein et al.   JOURNAL OF APPLIED TOXICOLOGY

Comparison of the metabolism of 10 cosmetics‐relevant chemicals in EpiSkin™ S9 subcellular fractions and in vitro human skin explants

(2019) Camille Géniès et al.   JOURNAL OF APPLIED TOXICOLOGY

Measurement of the penetration of 56 cosmetic relevant chemicals into and through human skin using a standardized protocol

(2019) Nicola J. Hewitt et al.   JOURNAL OF APPLIED TOXICOLOGY

Comparison of protocols measuring diffusion and partition coefficients in the stratum corneum

(2017) H. Rothe et al.   JOURNAL OF APPLIED TOXICOLOGY

Solvent Solubility Testing of Cosmetics-Relevant Chemicals: Methodology and Correlation of Water Solubility to In Silico Predictions

(2017) S. Grégoire et al.   JOURNAL OF SOLUTION CHEMISTRY

Comparison of the Skin Penetration of 3 Metabolically Stable Chemicals Using Fresh and Frozen Human Skin

(2017) Carine Jacques-Jamin et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

In Silico Modelling of Transdermal and Systemic Kinetics of Topically Applied Solutes: Model Development and Initial Validation for Transdermal Nicotine

(2016) Tao Chen et al.   PHARMACEUTICAL RESEARCH

Comparison of protocols for measuring cosmetic ingredient distribution in human and pig skin

(2016) D. Gerstel et al.   TOXICOLOGY IN VITRO

Suitability of skin integrity tests for dermal absorption studies in vitro

(2015) Katharina Guth et al.   TOXICOLOGY IN VITRO

Mathematical Model to Predict Skin Concentration after Topical Application of Drugs

(2013) Hiroaki Todo et al.   Pharmaceutics

Design and performance of a spreadsheet-based model for estimating bioavailability of chemicals from dermal exposure

(2012) Yuri Dancik et al.   ADVANCED DRUG DELIVERY REVIEWS

Mathematical and pharmacokinetic modelling of epidermal and dermal transport processes

(2012) Yuri G. Anissimov et al.   ADVANCED DRUG DELIVERY REVIEWS

Ethanol perturbs lipid organization in models of stratum corneum membranes: An investigation combining differential scanning calorimetry, infrared and 2H NMR spectroscopy

(2012) Sungjong Kwak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Prediction of Concentration–Time Profile and its Inter-Individual Variability following the Dermal Drug Absorption

(2012) Sebastian Polak et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Toward a Better Understanding of Pesticide Dermal Absorption: Diffusion Model Analysis of Parathion Absorptionin Vitroandin Vivo

(2010) Matthew A. Miller et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Skin Solubility Determines Maximum Transepidermal Flux for Similar Size Molecules

(2009) Qian Zhang et al.   PHARMACEUTICAL RESEARCH

In-silico model of skin penetration based on experimentally determined input parameters. Part I: Experimental determination of partition and diffusion coefficients

(2007) Steffi Hansen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The Transient Dermal Exposure: Theory and Experimental Examples Using Skin and Silicone Membranes

(2007) H.Frederick Frasch et al.   JOURNAL OF PHARMACEUTICAL SCIENCES