Perfluorooctanesulfonic acid (PFOS) administration shifts the hepatic proteome and augments dietary outcomes related to hepatic steatosis in mice

Environmental perfluoroalkyl acid exposures are associated with liver disease characterized by apoptosis and altered serum adipocytokines

(2019) John Bassler et al.   ENVIRONMENTAL POLLUTION

Early life exposures to perfluoroalkyl substances in relation to adipokine hormone levels at birth and during childhood

(2019) Colleen Shelly et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cardiovascular Risk in Non-Alcoholic Fatty Liver Disease: Mechanisms and Therapeutic Implications

(2019) Claudio Tana et al.   International Journal of Environmental Research and Public Health

The Effects of Physical Exercise on Fatty Liver Disease

(2018) Dirk J. van der Windt et al.   GENE EXPRESSION

A short review on human exposure to and tissue distribution of per- and polyfluoroalkyl substances (PFASs)

(2018) Jun-Meng Jian et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Paradoxical Protective Effect of Perfluorooctanesulfonic Acid Against High-Fat Diet–Induced Hepatic Steatosis in Mice

(2018) Ian Huck et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Selective Associations of Recent Low Concentrations of Perfluoroalkyl Substances With Liver Function Biomarkers

(2018) Ram B. Jain et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

A Never-Ending Story of Per- and Polyfluoroalkyl Substances (PFASs)?

(2017) Zhanyun Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

(2017) Naga Chalasani et al.   HEPATOLOGY

Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease

(2017) Chris Estes et al.   HEPATOLOGY

Multiplex and Label-Free Relative Quantification Approach for Studying Protein Abundance of Drug Metabolizing Enzymes in Human Liver Microsomes Using SWATH-MS

(2017) Rohitash Jamwal et al.   JOURNAL OF PROTEOME RESEARCH

Perfluoroalkyl acids-induced liver steatosis: Effects on genes controlling lipid homeostasis

(2017) Kaberi P. Das et al.   TOXICOLOGY

PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling

(2017) Mitchell B. Rosen et al.   TOXICOLOGY

Prevalence of non-alcoholic fatty liver disease and risk factors for advanced fibrosis and mortality in the United States

(2017) Michael H. Le et al.   PLoS One

Modeled Perfluorooctanoic Acid (PFOA) Exposure and Liver Function in a Mid-Ohio Valley Community

(2016) Lyndsey A. Darrow et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Pathophysiology of Non Alcoholic Fatty Liver Disease

(2016) Salvatore Petta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Impact of high-fat diet on the proteome of mouse liver

(2016) Outhiriaradjou Benard et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

PFOS induces adipogenesis and glucose uptake in association with activation of Nrf2 signaling pathway

(2016) Jialin Xu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Associations of perfluorinated chemical serum concentrations and biomarkers of liver function and uric acid in the US population (NHANES), 2007–2010

(2015) Jessie A. Gleason et al.   ENVIRONMENTAL RESEARCH

Mass-Spectrometry-Based Serum Metabolomics of a C57BL/6J Mouse Model of High-Fat-Diet-Induced Non-alcoholic Fatty Liver Disease Development

(2015) Yi-Syuan Lai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lowering Body Weight in Obese Mice With Diastolic Heart Failure Improves Cardiac Insulin Sensitivity and Function: Implications for the Obesity Paradox

(2014) Sowndramalingam Sankaralingam et al.   DIABETES

High Fat Diet Feeding Exaggerates Perfluorooctanoic Acid-Induced Liver Injury in Mice via Modulating Multiple Metabolic Pathways

(2014) Xiaobing Tan et al.   PLoS One

Perinatal Exposure to Perfluorooctane Sulfonate Affects Glucose Metabolism in Adult Offspring

(2014) Hin T. Wan et al.   PLoS One

Identification of Environmental Chemicals Associated with the Development of Toxicant-associated Fatty Liver Disease in Rodents

(2014) Laila Al-Eryani et al.   TOXICOLOGIC PATHOLOGY

PFOS induced lipid metabolism disturbances in BALB/c mice through inhibition of low density lipoproteins excretion

(2014) Ling Wang et al.   Scientific Reports

Profiles of perfluoroalkyl substances in the liver and serum of patients with liver cancer and cirrhosis in Australia

(2013) Leo W.Y. Yeung et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Accumulation of perfluoroalkyl substances in human tissues

(2013) Francisca Pérez et al.   ENVIRONMENT INTERNATIONAL

Evaluation of perfluoroalkyl acid activity using primary mouse and human hepatocytes

(2013) Mitchell B. Rosen et al.   TOXICOLOGY

PFOS-induced hepatic steatosis, the mechanistic actions on β-oxidation and lipid transport

(2012) H.T. Wan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Serum Perfluorooctanoate (PFOA) and Perfluorooctane Sulfonate (PFOS) Concentrations and Liver Function Biomarkers in a Population with Elevated PFOA Exposure

(2012) Valentina Gallo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Association between noninvasive fibrosis markers and mortality among adults with nonalcoholic fatty liver disease in the United States

(2012) Donghee Kim et al.   HEPATOLOGY

Tissue bioaccumulation patterns, xenobiotic biotransformation and steroid hormone levels in Atlantic salmon (Salmo salar) fed a diet containing perfluoroactane sulfonic or perfluorooctane carboxylic acids

(2011) Anne S. Mortensen et al.   CHEMOSPHERE

Alteration of Hepatic but Not Renal Transporter Expression in Diet-Induced Obese Mice

(2011) V. R. More et al.   DRUG METABOLISM AND DISPOSITION

Comparative pharmacokinetics of perfluorooctanesulfonate (PFOS) in rats, mice, and monkeys

(2011) Shu-Ching Chang et al.   REPRODUCTIVE TOXICOLOGY

Immunotoxicity of Perfluorinated Compounds: Recent Developments

(2011) Jamie C. DeWitt et al.   TOXICOLOGIC PATHOLOGY

Tissue distribution of 35S-labelled perfluorooctane sulfonate in adult mice after oral exposure to a low environmentally relevant dose or a high experimental dose

(2011) Jasna Bogdanska et al.   TOXICOLOGY

Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytes

(2011) J.A. Bjork et al.   TOXICOLOGY

Dietary exposure to perfluorooctanoate or perfluorooctane sulfonate induces hypertrophy in centrilobular hepatocytes and alters the hepatic immune status in mice

(2010) Mousumi Rahman Qazi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Gene Expression Profiling in Wild-Type and PPAR-Null Mice Exposed to Perfluorooctane Sulfonate Reveals PPAR-Independent Effects

(2010) Mitchell B. Rosen et al.   PPAR Research

Review: Treatment options for nonalcoholic fatty liver disease

(2010) Brian Lam et al.   Therapeutic Advances in Gastroenterology

Investigation of the Associations Between Low-Dose Serum Perfluorinated Chemicals and Liver Enzymes in US Adults

(2009) Chien-Yu Lin et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Immunotoxicity of Perfluorooctanoic Acid and Perfluorooctane Sulfonate and the Role of Peroxisome Proliferator-Activated Receptor Alpha

(2008) Jamie C. DeWitt et al.   CRITICAL REVIEWS IN TOXICOLOGY

Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6

(2008) Bente K. Pedersen et al.   PHYSIOLOGICAL REVIEWS

Gene Profiling in the Livers of Wild-type and PPARα-Null Mice Exposed to Perfluorooctanoic Acid

(2008) Mitchell B. Rosen et al.   TOXICOLOGIC PATHOLOGY

Activation of Mouse and Human Peroxisome Proliferator−Activated Receptor Alpha by Perfluoroalkyl Acids of Different Functional Groups and Chain Lengths

(2008) Cynthia J. Wolf et al.   TOXICOLOGICAL SCIENCES