Article
Otorhinolaryngology
Till F. Jakob, Iva Speck, Ann-Kathrin Rauch, Frederike Hassepass, Manuel C. Ketterer, Rainer Beck, Antje Aschendorff, Thomas Wesarg, Susan Arndt
Summary: The study aimed to compare long-term results after 1 year in patients with single-sided deafness (SSD) who were fitted with different hearing aids. Participants tested contralateral routing of signals (CROS) hearing aids and bone-anchored hearing systems (BAHS), with some also considering the possibility of a cochlear implant (CI). The study found that subjective impairment caused by SSD influenced patients' choices, with those with higher impairment more likely to opt for surgical treatment (BAHS or CI). Overall, cochlear implant (CI) showed the best results in terms of speech perception in noise, sound localization, and subjective outcomes.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Medicine, Research & Experimental
Nicholas L. Deep, Steven A. Gordon, William H. Shapiro, Susan B. Waltzman, J. Thomas Roland, David R. Friedmann
Summary: This study reviewed the experience of 14 pediatric patients under 18 years old who underwent unilateral cochlear implantation for single-sided deafness. The results suggest that cochlear implantation is a viable treatment option for pediatric patients with SSD, leading to improved speech perception and background noise control.
Article
Medicine, Research & Experimental
Nicholas J. Thompson, Margaret T. Dillon, Emily Buss, Meredith A. Rooth, Margaret E. Richter, Harold C. Pillsbury, Kevin D. Brown
Summary: Adult cochlear implant recipients with normal hearing experience significant improvements in sound source localization within the initial weeks of device use, with additional improvements observed after long-term use. Significant improvements between the 1-year and 5-year visits were noted, indicating greater accuracy and consistency in response patterns.
Article
Clinical Neurology
Heidi Olze, Manuel Christoph Ketterer, Dominik Peus, Sophia Marie Haeussler, Lynn Hildebrandt, Stefan Graebel, Agnieszka J. Szczepek
Summary: This study aimed to investigate the impact of cochlear implant (CI) treatment on tinnitus in patients with asymmetric hearing loss (AHL), single-sided deafness (SSD), and double-sided deafness (DSD). The results showed that tinnitus symptoms were alleviated, and improvements were seen in health-related quality of life, subjective hearing, and psychological comorbidities after CI treatment in all three groups of patients.
FRONTIERS IN NEUROLOGY
(2023)
Article
Otorhinolaryngology
Ankita Patro, Jourdan T. Holder, Christine L. Brown, Andrea DeFreese, Frank Virgin, Elizabeth L. Perkins
Summary: This study presents the experience of using cochlear implants (CIs) for children 5 years and younger with single-sided deafness (SSD). The results suggest that CI can safely be performed in younger children with SSD and can significantly improve their auditory and speech recognition abilities.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Medicine, Research & Experimental
Kevin D. Brown, Margaret T. Dillon, Lisa R. Park
Summary: The study demonstrates significant benefits of cochlear implantation in children with unilateral sensory hearing loss, including improvements in speech perception in quiet and noise, sound localization, and subjective hearing qualities. These findings suggest that cochlear implantation can effectively improve hearing outcomes in children with unilateral sensory hearing loss.
Article
Multidisciplinary Sciences
Jeroen P. M. Peters, Jan A. A. van Heteren, Anne W. Wendrich, Gijsbert A. van Zanten, Wilko Grolman, Robert J. Stokroos, Adriana L. Smit
Summary: In a Randomised Controlled Trial involving single-sided deafness patients, cochlear implants (CIs) were found to significantly improve speech perception in noise, sound localization, tinnitus burden, and quality of life compared to Bone Conduction Devices (BCD) and Contralateral Routing of Sound hearing aids (CROS).
Article
Neurosciences
Mohammed N. Ullah, Ashley Cevallos, Sarek Shen, Courtney Carver, Rachel Dunham, Dawn Marsiglia, Jennifer Yeagle, Charles C. Della Santina, Steve Bowditch, Daniel Q. Sun
Summary: This study explores auditory performance and real-world experience in patients with single sided deafness (SSD) who have undergone cochlear implantation (CI) with up to 10 years of auditory deprivation. The findings show that CI can improve auditory performance and subjective benefits even in patients with longer durations of deafness.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Otorhinolaryngology
Tom Gawliczek, Jeremie Guignard, Christoph Schmid, Wilhelm Wimmer, Marco Caversaccio, Martin Kompis, Stefan Weder
Summary: This study investigated the feasibility and benefits of using a cochlear implant (CI) processor as a contralateral routing of signals (CROS) device in unilateral CI recipients. The results showed improvements in word recognition scores and speech perception in both quiet and noise environments when using the CI processor as a CROS device. Patients who do not normally wear a hearing aid on the non-CI side reported satisfaction with the CROS device.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Otorhinolaryngology
Daniel M. Zeitler, Camille Dunn, Seth R. Schwartz, Jennifer L. McCoy, Carmen Jamis, David H. Chi, Donald M. Goldberg, Samantha Anne
Summary: This study evaluates the relationship between cochlear implantation (CI) and health-related quality of life (HR-QOL) in children with unilateral sensorineural hearing loss (USNHL) versus bilateral sensorineural hearing loss (BSNHL). The results show that USNHL children respond more favorably in 2 domains compared to BSNHL children, but there are no significant differences in other domains. Therefore, age and duration of hearing loss should not be absolute contraindications for CI in USNHL children.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Audiology & Speech-Language Pathology
Lisa R. Park, Margaret T. Dillon, Emily Buss, Kevin D. Brown
Summary: Children with severe-to-profound unilateral hearing loss lack access to binaural cues that support spatial hearing. Cochlear implant use in these children has been shown to improve speech recognition and localization abilities, although their performance remains poorer than their peers with normal hearing.
Article
Audiology & Speech-Language Pathology
Lisa R. Park, Amanda M. Griffin, Douglas P. Sladen, Sara Neumann, Nancy M. Young
Summary: More children with single-sided deafness are now receiving cochlear implants due to expanded indications. This unique group of pediatric patients requires special consideration and care, as their needs differ from those with bilateral deafness. The goal of cochlear implantation in these children is to provide bilateral input for the development of binaural hearing.
Article
Otorhinolaryngology
Tobias Rader, Oliver Julian Waleka, Sebastian Strieth, Klaus Wolfgang Georg Eichhorn, Andrea Bohnert, Dimitrios Koutsimpelas, Christoph Matthias, Benjamin Philipp Ernst
Summary: Cochlear implantation for patients with single sided deafness can improve their auditory perception and quality of life. The duration of deafness is not an independent negative predictive factor and should not be considered as a contraindication.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Medicine, Research & Experimental
Kayla B. Hicks, Lisa R. Park, Kevin D. Brown, Margaret T. Dillon
Summary: This study aimed to assess the perceived benefit of cochlear implant (CI) use for children with unilateral hearing loss (UHL) and evaluate whether perceived abilities are associated with performance on measures of speech recognition and spatial hearing. The results showed that parents reported significant improvements with CI use and these improvements were maintained or continued to improve over the 2-year post-activation period. However, perceived benefit did not significantly correlate with word recognition with the CI alone or spatial hearing outcomes in the combined condition.
Article
Audiology & Speech-Language Pathology
Margaret T. Dillon, Armine Kocharyan, Ghazal S. Daher, Matthew L. Carlson, William H. Shapiro, Hillary A. Snapp, Jill B. Firszt
Summary: This report reviews the current evidence and conducts a systematic review on the assessment and management of cochlear implant candidates and recipients with single-sided deafness (SSD). The findings are combined with expert consensus to provide guidance for the clinical assessment and management of adults with SSD.
Article
Audiology & Speech-Language Pathology
Robert H. Pierzycki, Padraig T. Kitterick
Summary: The study found that over half of adult cochlear implant users reported tinnitus, which was often persistent, emotionally distressing, and disruptive to sleep. Those with tinnitus were more likely to experience clinically abnormal insomnia, anxiety, and depression symptoms. The presence of tinnitus was associated with higher levels of insomnia, anxiety, depression, and tinnitus-related handicap, suggesting that these factors should be considered in the assessment and management of tinnitus in cochlear implant recipients.
Article
Audiology & Speech-Language Pathology
Robert H. Pierzycki, Mark Edmondson-Jones, Piers Dawes, Kevin J. Munro, David R. Moore, Padraig T. Kitterick
Summary: The study found that unilateral hearing impairment increases the risks of difficulties following conversations in noise and tinnitus, along with higher incidence of poor health and loneliness. However, compared to individuals with hearing impairment in both ears, those with unilateral hearing impairment still face higher risks of health issues and psychosocial problems.
Review
Medicine, Research & Experimental
Roulla Katiri, Deborah A. Hall, Catherine F. Killan, Sandra Smith, Pattarawadee Prayuenyong, Padraig T. Kitterick
Summary: This systematic review found significant variability in the reporting of outcome domains and instruments in studies evaluating the therapeutic benefits and harms of interventions for single-sided deafness in adults. Reports frequently lacked information on the intended assessment domains and the instruments used to measure those domains.
Article
Audiology & Speech-Language Pathology
A. Quentin Summerfield, Padraig T. Kitterick, Adele M. Goman
Summary: This study aimed to develop a preference-based measure that is sensitive to the contribution of binaural hearing to quality of life. The new measure demonstrated good psychometric properties, including construct validity, discrimination among different types of listening, and reproducibility. It did not exaggerate utility losses and showed a greater gain in utility from bilateral implantation compared to the EQ-5D.
Review
Audiology & Speech-Language Pathology
Catherine F. Killan, Derek J. Hoare, Roulla Katiri, Robert H. Pierzycki, Bethany Adams, Douglas E. H. Hartley, Danielle Ropar, Padraig T. Kitterick
Summary: This article presents the findings of a scoping review on the comparative outcomes of children with severe hearing-loss using hearing aids and cochlear implants. The review identified gaps in knowledge regarding children's quality of life, educational attainment, and complex listening and language outcomes. The results provide valuable insights for families, clinicians, researchers, and policy-makers.
Article
Clinical Neurology
Rebecca Susan Dewey, Robert A. Dineen, Matthew Clemence, Olivier Dick, Richard Bowtell, Padraig T. Kitterick
Summary: The study investigated the impact of cochlear implant (CI) positioning on brain magnetic resonance imaging artefacts. It found that the most postero-inferior CI positions resulted in the smallest apparent artefacts, while artefacts severely limited pathology detection in the ipsilateral temporal, parietal, and occipital lobes. Certain CI locations appeared to spare ipsilateral structures selectively, showing potential for informing surgical planning.
OTOLOGY & NEUROTOLOGY
(2021)
Article
Psychology, Experimental
Chatrin Suksasilp, Sarah Griffiths, Catherine L. Sebastian, Courtenay Norbury
Summary: The study evaluates the ability to use temporal distancing strategy to alleviate distress in younger and older adolescents, finding that adopting a distant-future perspective is most effective in reducing distress, with older adolescents showing even greater success. However, this ability may not be related to habitual use of this strategy.
Article
Otorhinolaryngology
R. S. Dewey, P. T. Kitterick
Summary: The study revealed varying opinions among cochlear implant users regarding the need for MRI, with many expressing concerns related to their implants. Therefore, there are opportunities for improvement in providing more accurate and timely information about MRI for CI users.
COCHLEAR IMPLANTS INTERNATIONAL
(2022)
Article
Neurosciences
Faizah Mushtaq, Ian M. Wiggins, Padraig T. Kitterick, Carly A. Anderson, Douglas E. H. Hartley
Summary: This study investigated brain responses to degraded speech in children using vocoded speech stimuli, finding significant sensitivity to stimulus intelligibility across several regions. More intelligible speech elicited stronger responses in temporal regions, predominantly within the left hemisphere, while right inferior parietal regions showed an opposite, negative relationship. The study suggests further understanding of cortical mechanisms underlying successful speech perception in children, with potential for fNIRS as a clinical tool to assess speech intelligibility in pediatric populations.
JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
(2021)
Article
Critical Care Medicine
Rachael A. Evans, Olivia C. Leavy, Matthew Richardson, Omer Elneima, Hamish J. C. McAuley, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Ruth M. Saunders, Victoria C. Harris, Raminder Aul, Paul Beirne, Charlotte E. Bolton, Jeremy S. Brown, Gourab Choudhury, Nawar Diar Bakerly, Nicholas Easom, Carlos Echevarria, Jonathan Fuld, Nick Hart, John R. Hurst, Mark Jones, Dhruv Parekh, Paul Pfeffer, Najib M. Rahman, Sarah Rowland-Jones, Ajay M. Shah, Dan G. Wootton, Trudie Chalder, Melanie J. Davies, Anthony De Soyza, William Greenhalf, Neil J. Greening, Liam G. Heaney, Simon Heller, Luke Howard, Joseph Jacob, R. Gisli Jenkins, Janet M. Lord, Will D-C Man, Gerry P. McCann, Stefan Neubauer, Peter J. M. Openshaw, Joanna Porter, Jennifer Quint, Matthew J. Rowland, Janet T. Scott, Malcolm G. Semple, Sally J. Singh, Mark Toshner, Keir Lewis, Andrew Briggs, Annemarie B. Docherty, Steven Kerr, Nazir Lone, Aziz Sheikh, Mathew Thorpe, Bang Zheng, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Ewen M. Harrison, Louise Wain, Christopher E. Brightling
Summary: This study aimed to describe recovery one year after hospital discharge for COVID-19 and identify potential therapeutic targets by analyzing inflammatory profiles. The results showed that a significant proportion of patients did not fully recover one year after discharge. Female sex, obesity, and invasive mechanical ventilation were associated with lower likelihood of full recovery. Inflammation and obesity may be treatable traits that need further investigation in clinical trials.
LANCET RESPIRATORY MEDICINE
(2022)
Article
Health Care Sciences & Services
Helen Cullington, Padraig Kitterick, Philippa Darnton, Tracy Finch, Kate Greenwell, Carol Riggs, Mark Weal, Dawn-Marie Walker, Andrew Sibley
Summary: This study aims to evaluate and rollout a person-centered remote care pathway for adults with cochlear implants in the UK. The pathway includes a personalized website and various tools and resources to improve patient empowerment, accessibility, and efficiency of care.
JMIR RESEARCH PROTOCOLS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Rebecca Susan Dewey, Richard Bowtell, Padraig Kitterick
Summary: This study investigates the clinical use of MRI in patients with cochlear implants (CIs) and examines the patient progression from referral to image reporting. The results show that the majority of CI users referred for an MRI successfully underwent imaging, with a high proportion of usable images. Healthcare professionals reported high levels of confidence in obtaining consent and acquiring images, but lower confidence in splinting, bandaging, and troubleshooting. Patient safety was prioritized, followed by patient comfort and image quality.
BRITISH JOURNAL OF RADIOLOGY
(2022)
Article
Medicine, Research & Experimental
Roulla Katiri, Deborah A. Hall, Derek J. Hoare, Kathryn Fackrell, Adele Horobin, Nicholas Hogan, Nora Buggy, Paul H. Van de Heyning, Jill B. Firszt, Iain A. Bruce, Padraig T. Kitterick
Summary: Single-sided deafness (SSD) has functional, psychological, and social consequences. Interventions for adults with SSD include hearing aids and auditory implants. However, there is inconsistency in reporting the benefits and harms of these interventions in clinical trials, preventing meaningful comparisons or syntheses of trial results. The CROSSSD initiative aimed to achieve consensus among healthcare users and professionals on a set of core outcome domains that are critically important to assess in all clinical trials of SSD interventions.
Article
Audiology & Speech-Language Pathology
Francisca Perea Perez, Douglas E. H. Hartley, Padraig T. Kitterick, Ian M. Wiggins
Summary: This paper presents the results of an online survey documenting the perceived listening difficulties of adult cochlear-implant (CI) users in various communication scenarios during the COVID-19 pandemic. The findings show that mask-wearing and physical distancing have significantly worsened in-person communication, and remote communication also poses challenges. The results underscore the importance of visual cues, such as lipreading and live speech-to-text transcriptions, in improving communication for CI users.
Article
Health Care Sciences & Services
Roulla Katiri, Deborah A. Hall, Derek J. Hoare, Kathryn Fackrell, Adele Horobin, Nora Buggy, Nicholas Hogan, Padraig T. Kitterick
Summary: The study team successfully achieved consensus for the CORESSD study using web-based methods, with majority of participants expressing satisfaction. However, there were methodological challenges in areas such as building rapport, understanding tasks, and managing unpredictability on the day of the meeting.
JMIR FORMATIVE RESEARCH
(2021)