Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease

Echocardiographic Follow-Up of Congenital Aortic Valvular Stenosis II

(2018) Ayşe Güler Eroğlu et al.   PEDIATRIC CARDIOLOGY

Drug and disease signature integration identifies synergistic combinations in glioblastoma

(2018) Vasileios Stathias et al.   Nature Communications

Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency

(2017) Christina V. Theodoris et al.   JOURNAL OF CLINICAL INVESTIGATION

Altered DNA Methylation of Long Noncoding RNA H19 in Calcific Aortic Valve Disease Promotes Mineralization by Silencing NOTCH1 Clinical Perspective

(2016) Fayez Hadji et al.   CIRCULATION

Effects of Raloxifene on the Proliferation and Apoptosis of Human Aortic Valve Interstitial Cells

(2016) Zhimin Fu et al.   Biomed Research International

Human Disease Modeling Reveals Integrated Transcriptional and Epigenetic Mechanisms of NOTCH1 Haploinsufficiency

(2015) Christina V. Theodoris et al.   CELL

Sequencing of NOTCH1, GATA5, TGFBR1 and TGFBR2genes in familial cases of bicuspid aortic valve

(2013) Ilenia Foffa et al.   BMC Medical Genetics

Estrogen-related receptor alpha interacts cooperatively with peroxisome proliferator-activated receptor-gamma coactivator-1alpha to regulate osteocalcin gene expression

(2013) Haibin Wang et al.   CELL BIOLOGY INTERNATIONAL

The Epidermal Growth Factor Receptor and Its Ligands in Cardiovascular Disease

(2013) Nader Makki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

GO-Elite: a flexible solution for pathway and ontology over-representation

(2012) Alexander C. Zambon et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome

(2012) J. J. Hofmann et al.   DEVELOPMENT

Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis

(2012) P. Vijayaraj et al.   DEVELOPMENT

Estrogen-related receptor α regulates osteoblast differentiation via Wnt/β-catenin signaling

(2012) Kathryn L Auld et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Limited Gene Expression Variation in Human Embryonic Stem Cell and Induced Pluripotent Stem Cell-Derived Endothelial Cells

(2012) Mark P. White et al.   STEM CELLS

C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes

(2011) Makoto Hirata et al.   HUMAN MOLECULAR GENETICS

Targeted RNA sequencing reveals the deep complexity of the human transcriptome

(2011) Tim R Mercer et al.   NATURE BIOTECHNOLOGY

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Characterization of a Novel Small Molecule Subtype Specific Estrogen-Related Receptor α Antagonist in MCF-7 Breast Cancer Cells

(2009) Michael J. Chisamore et al.   PLoS One